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      Nail #PsA, hard to treat and often overlooked. APEX trial: guselkumab achieved 43% ↓ in nail severity score (mNAPSI) v

      Jiha Lee JihaRheum

      2 months 1 week ago
      Nail #PsA, hard to treat and often overlooked. APEX trial: guselkumab achieved 43% ↓ in nail severity score (mNAPSI) vs 16% worsening on placebo at wk 24, plus PASI 100 in ~39% vs 11%. IL-23 inhibition delivering where pts often struggle most. @RheumNow #EULAR2026 POS0471
      BKZ protect joints in #PsA long-term?

      #POS0048: Phase 3 RCT+OLE (n=579):
      74% no x-ray progression at 3 yrs,
      across al

      Nelly ZIADE 🍀 Nellziade

      2 months 1 week ago
      BKZ protect joints in #PsA long-term? #POS0048: Phase 3 RCT+OLE (n=579): 74% no x-ray progression at 3 yrs, across all subgroups 💪 #EULAR2026 @RheumNow https://t.co/BftcHDKS4l
      💉 Risankizumab durable in #PsA?

      #POS0047 3 RCT n=964 KEEPsAKE
      Yes! ACR50 ~37% & MDA ~34% @w244
      no new safety sig

      Nelly ZIADE 🍀 Nellziade

      2 months 1 week ago
      💉 Risankizumab durable in #PsA? #POS0047 3 RCT n=964 KEEPsAKE Yes! ACR50 ~37% & MDA ~34% @w244 no new safety signals 💪 #EULAR2026 @RheumNow https://t.co/911Fi9vxfP
      🤔 Best endpoint for #PsA trials?

      #POS0046: GRAPPA-OMERACT NMA (24 trials, n=12,000):
      MDA wins! (OR 5.06) 📊

      #EUL

      Nelly ZIADE 🍀 Nellziade

      2 months 1 week ago
      🤔 Best endpoint for #PsA trials? #POS0046: GRAPPA-OMERACT NMA (24 trials, n=12,000): MDA wins! (OR 5.06) 📊 #EULAR2026 @RheumNow https://t.co/3KWaKcvF0a
      🤔 GUS or IL-17i for #PsA?
      #POS0045: RW study:
      Both! ~76% persistence & similar effectiveness
      1141 pts @12mo #PsA

      Nelly ZIADE 🍀 Nellziade

      2 months 1 week ago
      🤔 GUS or IL-17i for #PsA? #POS0045: RW study: Both! ~76% persistence & similar effectiveness 1141 pts @12mo #PsABIOnd 🌍 #EULAR2026 @RheumNow https://t.co/PyuaH5B5V1
      In #PsA, obesity isn't just a comorbidity, it's a disease modifier. Pooled SPIRIT trials (n=1284): 43% had obesity. BMI?

      Jiha Lee JihaRheum

      2 months 1 week ago
      In #PsA, obesity isn't just a comorbidity, it's a disease modifier. Pooled SPIRIT trials (n=1284): 43% had obesity. BMI≥30 vs normal: joint counts ↑, function ↓, fatigue ↑, CVD 55% vs 18%, HTN 52% vs 11%, DM 19% vs 3%. @RheumNow #EULAR2026 POS0460
      Does #Rx w #immunesuppression w
      #antifibrotic
      Help #SARD-ILD?

      YES.

      N=40 SARD-ILD, 1/2 w UIP pattern
      Use of #IS w #a

      Janet Pope Janetbirdope

      2 months 1 week ago
      Does #Rx w #immunesuppression w #antifibrotic Help #SARD-ILD? YES. N=40 SARD-ILD, 1/2 w UIP pattern Use of #IS w #antifibrotic pt group had better survival Small N and ?channeling bias But interesting results TAke home : Use IS + antifibrotic #EULAR2026 #POS0530 @RheumNow https://t.co/tfxVVw27jJ
      Guselkumab in erosive #PsA: ACR20 68% vs 47% placebo, structural damage progression ↓ across subgroups regardless of s

      Jiha Lee JihaRheum

      2 months 1 week ago
      Guselkumab in erosive #PsA: ACR20 68% vs 47% placebo, structural damage progression ↓ across subgroups regardless of sex, BMI, MTX use, or joint counts. Highest inflammation and erosion burden? Biggest benefit. IL-23i holds up where it matters most. @RheumNow #EULAR2026 POS0480
      CAR-T Cell Therapies in Refractory RMD
      • EULAR 2026 Press Release
      Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare. Recent anecdotal reports suggest that CD19-directed chimeric antigen receptor T (CAR-T) cell therapy may be an effective approach.
      Not all "difficult-to-treat" #PsA definitions are equal. Real-world DEPAR cohort (n=885): 20% met GRAPPA complex-to-mana

      Jiha Lee JihaRheum

      2 months 1 week ago
      Not all "difficult-to-treat" #PsA definitions are equal. Real-world DEPAR cohort (n=885): 20% met GRAPPA complex-to-manage vs only 4% EULAR difficult-to-manage criteria. Definition choice determines who gets identified, and who gets left behind. @RheumNow #EULAR2026 POS0446
      #EULAR2026 POS0044 TO ASPIRIN OR NOT in asymptomatic antiphospholipid antibodies (aPL) carriers? A study in Spain report

      Md Yuzaiful Md Yusof Yuz6Yusof

      2 months 1 week ago
      #EULAR2026 POS0044 TO ASPIRIN OR NOT in asymptomatic antiphospholipid antibodies (aPL) carriers? A study in Spain reported 4.6% VTE & 4.1% ATE. -Aspirin reduced thrombosis without increasing bleeding risk in asymptomatic aPL inc. those <3 lab points (isolated LA) @RheumNow https://t.co/NyVjAfjAKd
      SLE & Dengue infxn?
      This pop’n study from Brazil showed that #SLE pts who developed #dengue had sig. higher rates

      sheila RHEUMarampa

      2 months 1 week ago
      SLE & Dengue infxn? This pop’n study from Brazil showed that #SLE pts who developed #dengue had sig. higher rates of mortality, DHF & hospital stay length vs. gen popn These factors were found to have strong independent assoc w/SLE. Abs010 @rheumnow #EULAR2026 https://t.co/DTDPiQRlAf
      IL-23i vs IL-17i in PsABIOnd (n=1,141): 12mo persistence (~77%), joint/skin response, MDA, and PROs similar across both.

      Jiha Lee JihaRheum

      2 months 1 week ago
      IL-23i vs IL-17i in PsABIOnd (n=1,141): 12mo persistence (~77%), joint/skin response, MDA, and PROs similar across both. GUS matched IL-17i despite treating more biologic-experienced pts (15% vs 8% on 4th-line). GI AEs higher with IL-17i (11% vs 7%). @RheumNow #EULAR2026 POS0045
      What’s new in (WIN) PsA session. A preview of the BE BOLD study: Bimekizumab vs risankizumab on ACR50 in active #PsA

      Antoni Chan MD (Prof) synovialjoints

      2 months 1 week ago
      What’s new in (WIN) PsA session. A preview of the BE BOLD study: Bimekizumab vs risankizumab on ACR50 in active #PsA 49.1% vs 38.4% (p=0.008). The first head-to-head biologic trial to show joint superiority in PsA. Dual IL-17A/F blockade important. Abstr #LB0001 @RheumNow
      #EULAR2026 POS0440 1-Year Open Label Extension Study of 6-monthly Inebilizumab, a CD19 depleter in #IgG4 disease:

      -No f

      Md Yuzaiful Md Yusof Yuz6Yusof

      2 months 1 week ago
      #EULAR2026 POS0440 1-Year Open Label Extension Study of 6-monthly Inebilizumab, a CD19 depleter in #IgG4 disease: -No flare in INEB group; 6% flare in PBO-INEB -10.9% serious infections -1 pt discontinued due to low IgG Interested to see longer-term safety data @RheumNow https://t.co/PPUw81T8DZ
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