Monday, 28 May 2018

You are here

The RheumNow Week in Review - 9 March 2018

Dr. Jack Cush reviews highlights, news and recent research published this past week on RheumNow.com. This week's report includes news on new regulatory changes, new indication for tofacitinib, the rise and deficits of opioids and the benefits of fish and bariatric surgery.

  1. 30 pts with GCA were assessed by MRA - Less than half had normal MRA at baseline and MRA were weakly sensitive to Clinical change. This preliminary report suggests MRA is NOT useful or predictive in MRA https://t.co/aheWOMKtCE
  2. NICE reverses its Dec 2017 rejection and now approves Tocilizumab for use in Giant Cell Arteritis - specifically those with repeated relapses, or those who don't respond to steroids. https://t.co/tOmacr9ymX
  3. Comparing patients who travel by air vs those by land to/from hospital after TKR, THR, finds 3 fold higher rates of VTE (1.64% vs 0.58%) https://t.co/lFPk510fSv
  4. Study of 176 RA patients shows that those who eat fish 2 or more times per week have better disease control with significantly lower DAS28 scores. For each additional serving of fish per week, DAS28-CRP was significantly reduced by 0.18. https://t.co/vbsyv0SxSU
  5. Compared to diet/lifestyle modification in obese diabetic pts - bariatric surgery surgery patients are more likely to go off DM meds; 17 X more likely with gastric bypass, 7X more likely w/ Sleeve gastrectomy & 4X more likely w/ gastric lap band surgery. https://t.co/vYY2K0ow7J
  6. HUMOR trial - 51 pts shows that Humira is NOT effective in erosive OA - does not reduce pain, synovitis or BMLs after 12 weeks. https://t.co/bet8amKDZ9
  7. Rituximab associated adverse events are more common in treating lymphoma/leukemia ( 25-36%) than with autoimmune disease (9-17%) and are more common with splenomegaly, anemia, hx of allergies, age. https://t.co/gUREPFvbUb
  8. Tofacitinib - No dose adjustment is needed with mild renal impairment. Drug has not been studied in RA/PsA pts with baseline creatinine clearance < 40 mL/ min https://t.co/AvgEzObEAa
  9. FDA Panel Votes to Favor High Dose Xeljanz in Ulcerative Colitis  
  10. Opioid Overdoses Jump 30% in 2017 
  11. Opioids No Better than NSAIDs at Chronic Pain  
  12. Severe Stevens-Johnson and Toxic Epidermal Necrolysis Syndromes May Respond to Etanercept  

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

The RheumNow Week in Review – Methotrexate CIRT Study (5.25.18)

Dr. Jack Cush reviews this past week's news from RheumNow.com - the risk of Cutaneous and Systemic LE, increasing flu vaccination, higher risk of VTE, MPO predictions, new drug for GIOP and CIRT - MTX in cardiovascular risk patients.

ACR Leaders Lobby Capitol Hill for Help on Rising Costs and Access Barriers in Arthritis Care

Rheumatologists and rheumatology health professionals convened on Capitol Hill this week to urge legislative action on pressing policy issues affecting rheumatology care during the American College of Rheumatology’s Advocacy Leadership Conference, held May 16 -17, 2018 in Washington, D.C.

The RheumNow Week in Review – Modifiable Behavior (5.18.18)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  He discusses opioids, new approval for polyarticular JIA, running and osteoarthritis, and modifiable behaviors that influence outcomes. 

The RheumNow Week in Review - Nonadherence and Astronomic Costs (5.11.18)

Dr. Jack Cush reviews highlights, news and journal articles from the past week on RheumNow.com.

Rising Need for Weight Loss Counseling in Arthritic Patients

The CDC's May 4th MMWR reports that from 2002 to 2014, the prevalence of health care provider counseling for weight loss among adults with arthritis and overweight or obesity increased by 10% (from 35% to 45%).

Among the 54.4 million adults with doctor-diagnosed arthritis in the United States, 32.7% are overweight and 38.1% are obese. Moreover obesity is more prevalent among persons with arthritis than among those who do not have arthritis.