#volcosporin good ~lupus nephritis added to #MMF but underbelly - side effects like but ?less than #cyclosporin. #FDA update - ⬆️hypertension and nephrotoxicity, infection #ACR21 @RheumNow https://t.co/w5nLLSTlrB

• Dr. John Cush on Twitter: "FDA update: Voclosporin Safety in #SLE RCTs #AC…

"Baseline and routine EKGS are NOT required for SLE patients just because they are on HCQ!" - Dr. HM Belmont. "The drug has been demonized due to its use in COVID patients. We don't need to hold HCQ for EMR alerts (e.g, with cipro, SSRIs, etc)." Abstr#1743 #ACR21 @rheumnow https://t.co/5Bxavo6dRg

Post-hoc analysis of Deucravacitinib (TYK2i) for tx of PsA showed similar efficacy in pts with and without background csDMARD use. ⭐️>60% w/ background csDMARD use, majority of which was MTX ⭐️no difference in AE #ACR21 Abs#1352 @RheumNow https://t.co/nIJT7rNkJP https://t.co/bq0x1Ywguo

• Deucravacitinib Efficacy in Psoriatic Arthritis (PsA) by Baseline DMARD Use: Ex…

What predicts response to MTX in RA? 👉🏼DAS28-ESR 👉🏼RA duration 👉🏼Pt global assessment 👉🏼Swollen joint count Abs#1227 #ACR21 @RheumNow https://t.co/s942zvFiZ1

• Clinical Predictors of Response to Methotrexate in Patients with Rheumatoid Art…

#ACR21 #Abstr1420 A study checking #COVID vaccine response in 90 #lupus pts and 20 HC: ⬇️Titres of Abs in SLE vs controls 💠Factors of poor response: On any DMARDs exc HCQ only (OR 15) and normal dsDNA 📢Important to pause DMARDs in stable SLE @RheumNow https://t.co/USovFkiCRb https://t.co/bn5CC0xRS9

• Evaluation of SARS-CoV-2 Vaccine Response in a Multi-Racial/Ethnic Cohort of Pa…

Fautrel describes a series of 13 #AOSD (Stills) pts with Pulmonary arterial HTN (cath confirmed) - seen exclusively with women, 85% and all were on DMARDs - 31% MTX, 69% IL-1i, all on steroids- 5 deaths, 3 yr Survival 74% (same as PAH) #ACR21 Abstract 1100 https://t.co/qR21MdYG3A https://t.co/WN38ifgtT6

• https://bit.ly/3qiMuvi

#ACR21 Abs#1224. ⬇️ CD39 expression on B cell predicts occurrence of anti-drug Ab in RA on RTX ⭐️13/23 pts on RTX became ADAb+. No diff in concomitant MTX usage ⭐️Baseline CD73 similar, but lower CD39 predictive of ADAb https://t.co/QzbAmXtTmZ @Rheumnow https://t.co/CLtEev69YD

• https://bit.ly/2YpkRVG

Atypical patterns of HCQ retinopathy: - outside the central macula - missed by standard central macula screening - 41x more likely in Asians! Lesson: screening with extramacular SD-OCT for Asian HCQ pts is so, so important. 41x over. @MGHrheumatology #ACR21 ABST0989 @RheumNow https://t.co/0w7ALHJDSW