Sjogrens
3 years 2 months ago
#ACR21 #ACR2021
Sjogrens syndrome with pulmonary involvement guidelines
🚨Thread Alert
👉🏻Screen all patients for pulm inv. irrespective of symtopms ➡️ prevlance of lung involvement can be upto 65%
👉🏻Complete PFT includes ➡️ Spirometry➕ DLCO➕ PuseOximetry https://t.co/prFgQESRyF
3 years 2 months ago
#ACR21 #Abstr1908 Potential prognostic biomarker for lymphoma in #sjogren. ISG15 (IFN-I) expression was consistently ⬆️in pts with lymphoma vs none, both in blood and salivary gland biopsy. Work needed re: relation to other markers, ethnicity @RheumNow https://t.co/8VYYEXpXSw https://t.co/ZIkpx5kUfu
3 years 2 months ago
#Abstr0002 #ACR21 What drives salt in saliva in #sjogren? A study suggested Bcell cytokines mediated the epithelial Na+ Channel disruption. A case for targeting Bcell to improve oral health @RheumNow https://t.co/Bx3kBpOIFX https://t.co/YYnC6UoMJY
3 years 2 months ago
Knowledge Bowl at #ACR21
⭐️The first lung fibrosis described in Sjogren's with lung biopsy showing benign polyclonal lymphocytes and plasma cells with a risk for malignant transformation.
➡️Lymphocytic Interstitial Pneumonia
@RheumNow
Differentiation between a flare of disease and infection in patients with autoinflammatory (AI) conditions, where fever is the hallmark, can be extremely difficult. Promptly distinguishing…
3 years 2 months ago
Does concomitant SJS affect tx effectiveness in RA?
Abst#0839 suggest yes!
➡️RA+SjS have an inferior response to TNFi than RA patients w/o SjS
BUT, RA/SJS pts w/ longer RA dz duration & ↑ DAS28 + HAQ-scores.
What's your clinical experience with this?
#ACR21 @Rheumnow https://t.co/TIc3raMOSJ
3 years 2 months ago
Are these pictures representative of a Sjogren's tongue or oral candidiasis?
Comment below with your thoughts!
#ACR21 #ClinicalPearls
@RheumNow https://t.co/yGHA0pA7w0
3 years 2 months ago
Clinical Pearl at @ACR21
Is patchy tongue erythema + angular chelitis representative of Sjogren's or oral candidiasis?
Beware: Oral candiasis is a mimic of Sjogren's tongue.
Differentiate by asking if burning of tongue. If so, not Sjogren's -- start PO antifungal!
@RheumNow https://t.co/FbdiX8PFKV
3 years 2 months ago
#Abstr0002 #ACR21 What drives salt in saliva in #sjogren? A study suggested Bcell cytokines mediated the epithelial Na+ Channel disruption. A case for targeting Bcell to improve oral health @RheumNow https://t.co/Bx3kBpOIFX https://t.co/YYnC6UoMJY
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