OP/Bone
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2 years 8 months ago
Dr. Lane on Ca/Vitamin D in Osteoporosis
⭐️🎯serum vitamin D 25OH ~38
⭐️Studies since 2008 Auckland Calcium trial DO NOT support incr CV risk with Ca supplementation
⭐️Ca calculator: https://t.co/PLPMfZdIwb
⭐️No sig change in fracture risk with supp
#ACR21 #ACRAmbassador https://t.co/KUa52vf4gT
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2 years 8 months ago
Dr Adachi presents ⬆️BMD gain with denosumab than risedronate in RA. Non-significant reduction in fractures (very small numbers) Interesting, but need to see fracture benefit in larger study to justify dmab as first line Abstr#0445 #ACR21 @RheumNow https://t.co/GgaS9JZGzb
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2 years 8 months ago
A meta-analysis of 5 cohort studies showed that PsA is significantly associated with vertebral fractures pooled OR 2.09 (95% CI, 1.11 – 3.96; I2 70%). The review was not suggestive of publication bias
@RheumNow #ACR21 Abst#1304 https://t.co/rjC776FXUA https://t.co/QvMWxN6ZZ7
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2 years 8 months ago
Meta-analysis shows increased risk of vertebral fracture in PsA, OR 2.09. Abstr#1304 #ACR21 @RheumNow https://t.co/kTrR7I3HA0
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2 years 8 months ago
#ACR21 A#0563 - Is FRAX score applicable for RA? 10 yr Olmsted County epi study: Yes
▶️ 76 osteoporotic fxs in RA pts, FRAX predicted 67 fx (SIR 1.13, not signif)
▶️ 21 observed hip fx, FRAX predicted 23.3 (SIR 0.9)
⭐️ No differences by ages/sex
https://t.co/vWy7EmseZp @Rheumnow https://t.co/8BlzgQYqaV
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2 years 8 months ago
@jhrheumatology Dr. Petri at #ACR21 Great Debate.
Safety issues with Voclosporin:
1) Nephrotoxicity
2) Infection
3) CV Risk Factors
4) Malignancy
5) Neurologic toxicity
6) Osteoporosis
7) Drug interactions
8) Deaths
9) Pregnancy contraindication
@RheumNow https://t.co/wjluivmKNt
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