Osteoarthritis

Bella Mehta bella_mehta
3 years 11 months ago
Marc Hochberg lecture at #ACR21 - Bisphosphonates limited and inconclusive data in radiographic progression of OA, some ⬇️ in bone marrow lesions!
@RheumNow https://t.co/ciMUINBLwm


Dr. John Cush RheumNow
3 years 11 months ago
Dr. Marc Hochberg delivering the Oscar Gluck Memorial lecture - His talk titled "The Role of Bone in OA". He begins with this statement.... "DJD... Should never be used" - the rest of the lecture explains why. #ACR21 https://t.co/lYGsFu4Wpr https://t.co/IWP5J73mFO


sheila RHEUMarampa
3 years 11 months ago
MCP, wrist, elbow, shoulder and ankle: Not common sites for #osteoarthritis so consider a metabolic disease like CPPD🧐
@RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/utId4ljsZK


Bella Mehta bella_mehta
3 years 11 months ago
Phase 3 observational extension study of Lorecivivint, intra-articular CLK/DYRK inhibitor that modulates Wnt and inflammatory pathways. Safety and tolerability. Efficacy at 6 and 12 month, but at 18month it disappeared @RheumNow #ACR21 abst#0729 https://t.co/9ycbVGKkmy


Bella Mehta bella_mehta
3 years 11 months ago
Single Intraarticular Canakinumab in Knee OA - 18-week randomized, double-blind, double-dummy Placebo and naproxen-controlled - effect no different than Placebo. Some efficacy in subgroup with high hsCRP. Need for subtypes in OA @rheumnow #ACR21 #abst0728 https://t.co/YlKTMf56wF


Janet Pope Janetbirdope
3 years 11 months ago
Rx of knee OA. A step in the right direction? Many knee #OA studies show that exercise can help pain and maybe much more - strengthening, alignment, tone, maybe weight loss. Here is a trial - STEP-KOA to support it. #YearInReview #ACR21 @RheumNow https://t.co/rTZUeZuT1c

TheDaoIndex KDAO2011
3 years 11 months ago
answer: CPPD.
👉CPPD can look like OA but can be more aggressive.
👉Look for chondrocalcinosis at the triangular ligament, pubic symphyis, superiolateral femoral head
👉A common cause of scapholunate widening
👉CPPD loves the patellofemoral joint (knee joint may be spared) https://t.co/wgYjJwYvb0


Bella Mehta bella_mehta
3 years 11 months ago
Wanted to highlight our work @HSpecialSurgery presented at #ACR21 using unsupervised clustering of multimodal data - histology and ultrasound to identify phenotypes such as moderately inflammatory subtype in #osteoarthritis @RheumNow #abst0212
some features highlighted in fig https://t.co/HRzhMXctB9


TheDaoIndex KDAO2011
3 years 11 months ago
Pearls on Rheum imaging:
👉CPPD is not erosive
👉SC joint in OA is common (hard to image)
👉AC joint is 1st place OA affects shoulders (not GH)
👉Neuropathic OA progress rapidly, look at the TMTs
👉Get more views if you aren't seeing what you need
#ACR21 Radiology Bootcamp

sheila RHEUMarampa
3 years 11 months ago
STEP-KOA trial: a promising intervention for knee #osteoarthritis?🤔
@RheumNow #ACR21 #YearinReview https://t.co/6Vkx0WR0tx


Eric Dein ericdeinmd
3 years 11 months ago
#ACR21 Year in Review: Stepped Exercise program for knee OA - decrease in pain and increase in function, without objective measures showing improvement. Time to prescribe exercise! @Rheumnow https://t.co/LrNZ3pBO9i


Bella Mehta bella_mehta
3 years 11 months ago
How to improve clinical care for knee OA? stepped exercise program helps WOMAC self reported pain outcomes in Knee OA Important RCT #ACR21 year in review by @karen_kc123 @RheumNow
@AnnalsofIM here is a paper https://t.co/RGIjBL9TuZ