Rheumatoid Arthritis
3 years 1 month ago
#ACR21 Ab#1939: Tofa CV Outcome (STAR-RA)
▶️Pooled data does not show ⬆️ risk of CVD
▶️Trend in pts w prior CVD -HR 1.27 (0.95-1.7), cannot r/o CVD risk in pts w risk factors
Less clear than oral surveillance data, but concerns in those w risks
https://t.co/JOKNyYVZfX @Rheumnow https://t.co/GGYJfxcqhc
3 years 1 month ago
Why is there more CHF in #RheumatoidArthritis ? Also dose response between highest inflammation RA the PsA then axSpA then PsO. ?Cytokine profile varying with disease and maybe CRP. Who knows. Abst#1925 #ACR21 @RheumNow https://t.co/JIH3qwkLpx
3 years 1 month ago
Should we be measuring drug levels in pts taking infliximab?
⭐️Drug monitoring vs. standard dosing showed 73% sustained control vs. 55% (RA, PsA, SpA, UC, Crohn's, PsO)
#ACR21
Abs#1946
#ACRBest @RheumNow
https://t.co/sWMen50ljP https://t.co/F4Wpqis3id
3 years 1 month ago
Anti-MAA Ab is not ‘baa’ humbug. In prevalent #RheumatoidArthritis, + MAA Ab was predictive of developing #RA #ILD. ? Novel biomarker. Needs validation but nice convincing data @RheumNow #ACR21 #ACRBest abst#1916 https://t.co/wuTPzSIsey
3 years 1 month ago
Another study linking long term GC and CV risk in RA!
Medicare data >65yo 130000+ pts
1-year incidence CV ⬆️ as follows:
📍Dose ≤5mg 1.4%
📍Dose 5-10mg 1.7%
📍Dose >10mg 1.9%
Not replicated in younger pts (Optum data)
#ACR21 #Abst1915 @RheumNow https://t.co/DLXdfvfiBW
3 years 1 month ago
Abst 1916
England & colleagues determined if anti-MAA Ab = predictor of incident RA-ILD
- Anti-MAA Ab significantly associated w/ incident RA-ILD
- Strongly associated w/ higher concentrations anti-MAA
- Antibody associations = antigen/isotype dependent
#ACR21 @RheumNow https://t.co/z1RspmxBvc https://t.co/hvUm4O6RmX
3 years 1 month ago
DAS-28 independently associated survival in RA-ILD. As I keep saying, treating the rheumatoid disease properly is the current best strategy for treating RA-ILD. Abstr#1918 #ACR21 @RheumNow #ACRBest https://t.co/FpUK6upyOi
3 years 1 month ago
Is there a relationship between the weather and RA disease activity?⛈️
#ACR21 Abs#1912
🌡️Temperature & humidity significantly affect pain, TJC & SJC
🌦️PGA was mostly influenced by humidity
Should we take the weather into account when assessing patients?
@RheumNow https://t.co/e3PewZWkLR