My video take on this from yesterday for @RheumNow: '11 Ways to Stay Away From RA' #ACR21 https://t.co/ELZaL1A20i https://t.co/bynPNibk3q

• 11 Ways to Stay Away From RA: Dr. David Liew | RheumNow
• David Liew on Twitter: "After elegantly laying out the sophisticated scien…

#ACR21 Abst#0588. TNF vs non-TNFi in obese RA pts ⭐️TNFi use ⬆️ disease activity vs ABA in obese pts ⭐️TNFi use ⬆️ activity vs TCZ in non-obese pts ⭐️No diff w RTX, Tofa ▶️Further research needed: Wt-based dosing? SC vs IV? https://t.co/K8WycPTgxW @Rheumnow #ACRBest

• https://bit.ly/3H1GMDI

ORAL Surveillance MACE conclusions: So this is fair: tofacitinib acts as a CV risk factor, there are many others, we need to address CV risk in RA pts. Nevertheless, in terms of MI risk, tofa vs TNFi, if I had one CV risk factor, I know what I'd do. #ACR21 ABST0958 @RheumNow https://t.co/4Z79XtTzl9

For what it's worth, I'm struck by my conversation last week with one RA patient in clinic with stents. 3y ago post-MTX/HCQ had asked for a JAKi first line, immaculate RA response. Listened, no blinking, okay thanks doctor - I'm happy where I am. Next question. #ACR21 @RheumNow

“For many patients, it doesn’t matter if there’s an increased risk, because they don’t want to go to the alternative” - Christina Charles-Schoeman, presenting ORAL Surveillance MACE data in the #ACR21 plenary Discussions with pts needed, these data justify that need. @RheumNow

Googling rheumatic diseases. On average google search lacked essential information to guide patient decisions. Websites on AS scored the highest on the DISCERN and RA scored the highest on JAMA @RheumNow #ACR21 Abst#0742 https://t.co/k2o2AqYEeh https://t.co/ZKljvA2f4O

• Googling Rheumatic Diseases: Evaluating the Reliability of Information Found on…

🌞😎🍣 Vitamin D and Omega-3 FA ⬇️ Risk of developing autoimmune disease 1st prospective, randomized, double blind, placebo controlled trial Vit D 2000IU and/or Omega 3-FA 1000mg ⬇️autoimmune disease by 25-30% #ACR21 #ACRBest @RheumNow Abs#957 https://t.co/7dODuplg7e https://t.co/GUKhYXbSXU

• Vitamin D and Marine n-3 Fatty Acid Supplementation and Prevention of Autoimmun…

ORAL Surveillance: MACE events higher in TOFA vs TNFi. Independent risk factors: smoking, aspirin use, age ≥ 65 yrs, and male sex; TOFA vs TNFi tx in these pts assoc'd w/ numerically higher MACE incidence. Plenary Abs 0958 #ACR21 #ACRbest @RheumNow https://t.co/44af1KujqP

• Risk Factors for Major Adverse Cardiovascular Events in Patients Aged ≥ 50 Year…

Do you order EKGs in everyone starting HCQ? Do you avoid HCQ in patients with heart failure? Will these abstracts impact your practice? Click on link to read more....#ACR21 @rheumnow #HCQ https://t.co/fvUZAvNWa8

• Dr. John Cush on Twitter: "Prolonging the Controversy of Hydroxychloroquin…

Abstr 0584 Patients in GLORIA Study noted to have - High number of comorbidities (median 6) - Multiple medications notably HTN and GI protection Findings represent medical reality of elderly RA patients (>65 years old) #ACR21 @RheumNow https://t.co/2cOtO9MLNM

• High Number of Comorbidities and Concomitant Medications at Baseline in the Glu…

Awesome presentation today from Dr. Cristina Ruiz-Romero on lipidomic profiles in RA vs PsA. Using mass spectrometry, found differences in both synovial bx and fluid. Potentially useful lipid markers, more studies to follow. #ACR21 #ACRBest Abst#0946 @RheumNow https://t.co/KmWCPKijSx

Tofacitinib vs TNF inhibitors in #RA patients +50yrs with >1 CV risk factor; the data from ORAL Surveillance that we have all been waiting for! #ACR21 Risk of MACE related largely to baseline CV risk https://t.co/SpuKTtP8ql

#ACR21 #ACRAmbassador Fascinating analysis of rheum dx from the (negative!) VITAL study (https://t.co/aMtMCIf1F1) Very few pts 278/25,871 (1.1%) but HR 0.78, p = 0.045 for vitamin D preventing autoimmune disease Do you believe it? If so, what's your public policy advice? https://t.co/ZkO5nHAJz9

• https://www.nejm.org/doi/full/10.1056/nejmoa1809944

ORAL-Surveillance, an open label Phase 3b/4 RCT of tofacitinib (JAKi) vs TNFi in RA Numerical elevations in MACE and MI, highest among pts w/hx of CAD or high 10-year risk for MACE I have been considering baseline CVD / VTE / CA risk when prescribing these since this broke https://t.co/8DAx8IgnZM