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TNF inhibitor

      RT @RichardPAConway: Dr Jin @SeoyoungCKim population-based study on predictors of switching after 1st line TNFi use. 22%

      Richard Conway RichardPAConway

      3 years 10 months ago
      Dr Jin @SeoyoungCKim population-based study on predictors of switching after 1st line TNFi use. 22% switch, most to 2nd TNFi.👩, prior steroid use predicted change, other autoimmune disease and vit D use negative predictors. Abstr#579 #ACR21 @RheumNow https://t.co/YpZ5rGBiod
      RT @RichardPAConway: @MilenaGianfran @JYazdanyMD present on differential effects of biologics on CDAI in obese patients

      Richard Conway RichardPAConway

      3 years 10 months ago
      @MilenaGianfran @JYazdanyMD present on differential effects of biologics on CDAI in obese patients with rheumatoid arthritis. Abatacept better than TNFi in obese. Tocilizumab better than TNFi in non-obese. Abstr#0588 #ACR21 @RheumNow #ACRBest https://t.co/UcEpMAmNVw
      RT @doctorRBC: No significant difference in effectiveness/treatment survival of different TNFi in axSpA
      Failure of 1st T

      Robert B Chao, MD doctorRBC

      3 years 10 months ago
      No significant difference in effectiveness/treatment survival of different TNFi in axSpA Failure of 1st TNFi did not diminish effectiveness of a second TNFi Abs#938 #ACR21 @RheumNow https://t.co/SLrOV7wmvU https://t.co/fkpmseVwF6
      RT @AkhilSoodMD: Abstr 0579
      Kim & Colleagues examined predictors of Tx change among RA patients w/ TNFi as 1st line

      Akhil Sood MD AkhilSoodMD

      3 years 10 months ago
      Abstr 0579 Kim & Colleagues examined predictors of Tx change among RA patients w/ TNFi as 1st line biologic agent - Females & GC use more likely to switch agent - Vitamin D use & hx of other immune-mediated diseases (eg. Psoriasis, IBD) less likely to switch #ACR21 @RheumNow https://t.co/FM5mSWmSNA
      RT @uptoTate: No evidence to show increased risk of incident hypertension w/ TNFi use, after accounting for baseline &am

      Dr. Rachel Tate uptoTate

      3 years 10 months ago
      No evidence to show increased risk of incident hypertension w/ TNFi use, after accounting for baseline & time-dependent confounding factors, in prospective AS cohort. Abs 0910 #ACR21 #RheumNow @RheumNow https://t.co/1SpQ51ftlK
      RT @uptoTate: French, real-world axSpA cohort analysis shows SEC and TNFi retention rates similar. What do you see in yo

      Dr. Rachel Tate uptoTate

      3 years 10 months ago
      French, real-world axSpA cohort analysis shows SEC and TNFi retention rates similar. What do you see in your practice? Abs 0911 #ACR21 #RheumNow @RheumNow https://t.co/vu3zUwfktl https://t.co/v6DLjWJMn4
      The RheumNow faculty have been glued to their monitors all day, watching video, and running down abstract presentations to find the best – several of these stood out as #ACRBests. Here is a listing of “Best” they saw on Day 1.
      Patients with axial spondyloarthritis (axSpA) often have increased absence from work as well as reduced productivity at work, which can have profound impacts for not only the affected individual and their families, but also lead to wider economic and social burden.
      RT @RichardPAConway: @rheum_cat presenting a really well designed study looking at association between TNFi use and inci

      Richard Conway RichardPAConway

      3 years 10 months ago
      @rheum_cat presenting a really well designed study looking at association between TNFi use and incident hypertension in axSpA. No association found. Abstr#0910 #ACR21 @RheumNow https://t.co/w7o1oDreVL
      In rheumatoid arthritis we have a wide range of options available to us when we progress to a biologic treatment option. We have little to differentiate between these agents based on the clinical trials. We often make our choices based on minor hints from clinical features, comorbidities, or cost considerations.
      RT @RichardPAConway: And here is ORAL-Surveillance, small increase in MACE and malignancy with tofacitinib vs TNFi. 1 ex

      Richard Conway RichardPAConway

      3 years 10 months ago
      And here is ORAL-Surveillance, small increase in MACE and malignancy with tofacitinib vs TNFi. 1 extra MACE per 319-567 patient years, 1 extra malignancy per 275 patient years. Abstr#0831 #ACR21 @RheumNow https://t.co/wMJnspTTBy
      RT @doctorRBC: Drug retention of TNFi vs. secukinumab in AxSpA pts
      Abs#911
      ⭐️46% discontinued either treatment
      ⭐ï

      Robert B Chao, MD doctorRBC

      3 years 10 months ago
      Drug retention of TNFi vs. secukinumab in AxSpA pts Abs#911 ⭐️46% discontinued either treatment ⭐️TNFi with slightly better drug retention ⭐️Age, BASDAI, BMI did not favor any group ⭐️inefficacy - main reason #ACR21 @RheumNow https://t.co/ynoomYrTvX
      RT @drdavidliew: So it's day 2 at #ACR21, and you know what that means - it's ORAL Surveillance day!

      This is the figure

      David Liew drdavidliew

      3 years 10 months ago
      So it's day 2 at #ACR21, and you know what that means - it's ORAL Surveillance day! This is the figure everyone will be talking about, leading up to details in the plenary. Why are the other bars higher than the pink bars? ABST0831 plenty of @RheumNow coverage coming on this https://t.co/B80cSmhNV7
      RT @drdavidliew: ORAL Surveillance
      In mod-severe RA pts >50yo, with CV RF & no hx malignancy, patient-years of ex

      David Liew drdavidliew

      3 years 10 months ago
      ORAL Surveillance In mod-severe RA pts >50yo, with CV RF & no hx malignancy, patient-years of exposure required for one event (vs TNFi): MACE tofa 5mg bid: 567 tofa 10mg bid: 319 malignancy tofa 5mg bid: 276 tofa 10mg bid: 275 #ACR21 ABST0831 @RheumNow https://t.co/9vyXPTMFzj
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