Vasculitis
3 years 1 month ago
Knowledge Bowl at #ACR21
⭐️In a suspected PAN case, you order a peripheral smear to look for this potential etiology,
➡️Hairy cells
@RheumNow
3 years 1 month ago
Knowledge Bowl at #ACR21
⭐️Increased susceptibility to a certain most common adult vasculitis is conferred by this HLA allele
➡️HLA DRB10404
@RheumNow
Differentiation between a flare of disease and infection in patients with autoinflammatory (AI) conditions, where fever is the hallmark, can be extremely difficult. Promptly distinguishing…
3 years 1 month ago
#ACR21 Knowledge Bowl Final Question: Vasculitis Mimics: @RheumNow https://t.co/laD3oO8Uq9
3 years 1 month ago
Knowledge Bowl at #ACR21
⭐️This HLA allele can be seen in a certain vasculitis where panuveitis is a possibility and has a venulitis predilection
➡️HLA B51
@RheumNow
3 years 1 month ago
One of the most provocative & interesting abstracts the GCA space at #ACR21 -so many sides to consider- I will be discussing at @RheumNow Panel w @drdavidliew WEDS AM @AdamJBrownMD @CCalabreseDO @CleClinicMD #vasculitis @EBRheum @anisha_dua https://t.co/STR9gNPdsO
3 years 1 month ago
TCZ in GCA: one disadvantage is that you can't use CRP+/- ESR for flares
Mavrilimumab in GCA:
- CRP/ESR consistently go up with symptomatic flares
- CRP/ESR up less (cf. placebo), in the absence of Sx flares
More signal, less noise.
phase 2 post-hoc #ACR21 ABST1401 @RheumNow https://t.co/c0lMJMcQv0
3 years 1 month ago
Baricitinib for *relapsing* GCA (Th1+Th17)
w abbreviated steroid wean (15-22w)
Despite being tougher to treat:
100% off steroids at 24w
93% off steroids at 52w
no ischemic Sx
promising as another GCA Rx option!
(post-cessation 4pts flared)
@MayoClinic #ACR21 ABST1396 @RheumNow https://t.co/dqFnHQYogk
3 years 1 month ago
"GCA is not a single, monolithic disease"
- Christian Dejaco, rightfully asking why we don't stratify treatment/trials in GCA
#ACR21 PMR/GCA Study Group @RheumNow @Sarah_L_Mackie @profbdasgupta @EBRheum @RichardPAConway @SattuiSEMD @drceowen