Dr. John Cush RheumNow
3 years 1 month ago
ARIAA Study - Abatacept Reverses ACPA+ Subclinical Arthritis: Dr. Jack Cush discusses abstract #0455, a preclinical RA intervention trial - abatacept or placebo given to at risk individuals (arthralgias, CCP+, MRI+) for 6 months, presented at #ACR21.
https://t.co/fz1hPTleMn https://t.co/V4PsPZ0ZwF
Dr. John Cush RheumNow
3 years 1 month ago
5 yr multinational PROOF study - enrolled 1612 axSpA pts enrolled (65% xray+ axSpA; 35% nr-axSpA) nraxSpA had more enthesitis, PSO IBD. Over time, more TNFi use (less NSAIDs) w/ less disease activity #ACR21 Abst #0363 https://t.co/5DdDlCjq9h (Graph: NSAID use over time) https://t.co/5JE69vTIy9
David Liew drdavidliew
3 years 1 month ago
Quick plug:
not all joint pain in ICI-treated pts needs reflex steroids
eg OA can get exacerbated by ICI Rx
(ICI-aOA)
call rheum, hold the PNL & save tumor response
@ReidMDMPH @got_rheum @lovetolearn27 +me
#ACR21 ABST1518 @RheumNow
our paper @jitcancer https://t.co/InespbOn6m https://t.co/HSjtGrwePE
Janet Pope Janetbirdope
3 years 1 month ago
Glory to GLORIA trial? Low dose prednisone 2mg in active RA>65yrs, N=451 All Standard care. in 2yrs, ~40% drop out- same in each grp Better RA control but NNH 9.5 w steroids, mostly non severe infections. So, prednisone debate in RA continues #ACR21 @RheumNow #ACRBest abst#1678 https://t.co/emOaYSjYAa
Dr. Rachel Tate uptoTate
3 years 1 month ago
Pregnant pts w/ PsA, but not AxSpA, at increased risk of pre-eclampsia. In RA pregnancies, pre-eclampsia risk increases w/ dz severity prior/during pregnancy. We need to discuss potential risks w/ pts and OB team. Abs 1722 #ACR21 #RheumNow @RheumNow https://t.co/yeQmNAZ1jV https://t.co/cBfeVKQHfr
David Liew drdavidliew
3 years 1 month ago
Just worthwhile remembering:
in terms of TNFi anti-drug immunogenicity in autoimmune disease:
RA is top of the pops
(although dose spacing is worse)
data from NOR-DRUM A, TDM in infliximab #ACR21 ABST1525 @RheumNow https://t.co/wfcA72wcLP https://t.co/mHppH6qYdY
TheDaoIndex KDAO2011
3 years 1 month ago
ANA negative SLE! Lunch w/Dr. John P Atkinson. When I was in training @WUSTLrheum he bet that if you come across a case of ANA neg- SLE that is convincing, he will buy lunch. Great case of SLE following spont coronary artery dissection. #ThievesMarket #ACR21 Abst#TM18 @rheumnow https://t.co/TRyQaJ4kbR
Eric Dein ericdeinmd
3 years 1 month ago
Fun things at #ACR21. Abs1186 #Kardashian index:
K-index = # of followers on Twitter/expected # of followers based on citations.
⭐️Only 1 program director (PD) had K-index>5, an "academic Kardashian"
⭐️Only 11 PDs on Twitter had >100 followers
https://t.co/uH408ri5nY @Rheumnow https://t.co/d8VeyzAIcU
TheDaoIndex KDAO2011
3 years 1 month ago
Impressive case of vasculitis – should be part of @ACRheum image bank #ThievesMarket #ACR21 Abst#TM20 @rheumnow https://t.co/YiBikROuzb
TheDaoIndex KDAO2011
3 years 1 month ago
They are the up and coming leaders in our field! I got to interview them about
👉🏼why #GeriRheum is important (our pts are aging)
👉🏼small changes to your practice for big outcomes
👉🏼Tips: pain control/funx #acr21 @UnaMakris @RheumNow https://t.co/f71L0P3foE via @YouTube
Richard Conway RichardPAConway
3 years 1 month ago
Pirfenidone in RA-ILD, TRAIL-1 study. Long-awaited. Early termination due to COVID led to under-powering. Slowed decline in FVC, especially in UIP pattern. Seemed to have less adverse events than we see with nintedanib. Abstr#L10 #ACR21 @RheumNow https://t.co/sYRDhG3u4y
Dr. Antoni Chan synovialjoints
3 years 1 month ago
Artificial neural network showed good generalizability and a high specificity with acceptable sensitivity in the detection of radiographic sacroiliitis. A tool for interpretation of sacroiliac radiographs as a part of the diagnostic approach @RheumNow #ACR21 Abst#1919 #ACRbest https://t.co/SdmomEWwya
Janet Pope Janetbirdope
3 years 1 month ago
New dimensions in cellular immunology. Great session, some which I understood. Kids with #JIA have more cytolytic pathway missense - some leads to macrophage activation syndrome #MAS Low NK cells in Juvenile Dermatomyositis. 9T112 #ACR21 @RheumNow https://t.co/5lUkqr65UM
Aurelie Najm AurelieRheumo
3 years 1 month ago
Adipokines in RA
⚡️Highest Quartile Adiponectin associated w/ ⬆️ all-cause mortality HR 1.46 ⬆️ CV mortality HR 1.85
⚡️Highest Quartile Leptine ⬆️ 25% all-cause mortality
#ACR21 #Abst1645 @RheumNow
https://t.co/O1NAbfMvif https://t.co/VVdgZHP1j5