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David Liew drdavidliew
3 years 1 month ago
My video comment on the cannabidiol (CBD) double-blinded RCT in hand OA/inactive PsA #ACR21 for @RheumNow
Great work by @Joner_MD et al
& kudos to funders @PsoriasisDK @Gigtforeningen @AalborgUH @aalborguni giving us data to answer a question often asked
https://t.co/e0mO0SriUu https://t.co/9DveN4jLls
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 1 month ago
#ACR21 #Abstr1541 Any tools to help differentiate MAS vs #COVID inflammatory response? Preliminary criteria showed Sensitivity: 79.6%; Specificity: 81.3% within 6 days admission. No Triglyceride/Fibrinogen compared to 2016 ACR-EULAR & 2004 HLH @RheumNow https://t.co/c7pHaVCr5S https://t.co/6irF64qizI
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 1 month ago
#ACR21 #Abstr1876 The fact that nothing is 100% makes Medicine interesting! If you have patients who meet McAdams/Damiani criteria for relapsing polychondritis OR ICBD for Behcet, don’t forget it could be MAGIC! Anticollagen II abs may help @RheumNow https://t.co/9ZjYbWC6Td https://t.co/xbh9ahp2fh
Dr. Antoni Chan synovialjoints
3 years 1 month ago
Guselkumab 100 mg Q4W and Q8W provided robust and sustained benefits to patients with active PsA across multiple domains. Listen to my interview with Prof. Laura Coates on this and other emerging treatments in PsA here https://t.co/PSbJ0HA5a6
@RheumNow #ACR21 Abstr#1335 https://t.co/WzBOYGOxAA
David Liew drdavidliew
3 years 1 month ago
Will a FDA black box warning change your JAKi practice?
In May 2019, the EMA put out a warning about VTE with tofacitinib.
In this French cohort, did it change the kind of pts they initiated on JAKi?
no, not it did not😊
A window into the US future?
#ACR21 ABST1245 @RheumNow https://t.co/QI95E1gepg
David Liew drdavidliew
3 years 1 month ago
Are there people looking at steroid-sparing therapy as irAE treatment or prevention?
@CCalabreseDO: are there ever
#ACR21 irAE Study Group @RheumNow
(also @NAbdelwahabMD @ReidMDMPH on stage) https://t.co/CLmNaLB68O
Mrinalini Dey DrMiniDey
3 years 1 month ago
#ACR21 Abs#1536
#Vaccine uptake in people with #RheumaticDisease
👉🏼High uptake of vaccines in ~240 pts @BrighamWomens
👉🏼84% pts wanted the #COVID19 vaccine
👉🏼Physician recommendation was key determinant of uptake
@RheumNow
https://t.co/us0i5CW5Mi https://t.co/aLZmOPWFR3
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 1 month ago
#ACR21 #Abstr1492 Could gut microbiome contribute to Anti-Ro+/autoimmunity in #lupus? Analyses of 125 stool samples from mother of children with neonatal lupus and/or heart block revealed its potential role in genetic-environment interaction @RheumNow https://t.co/FnJtZJSCRj https://t.co/ttRdP9NIrG
Mrinalini Dey DrMiniDey
3 years 1 month ago
Safety profile of #upadacitinib in #RA, #PsA, #AnkylosingSpondylitis
👉🏼AE rates similar across UPA, ADA & MTX in RA, and UPA & ADA in PsA
👉🏼No new safety risks with long-term use
👉🏼#Herpeszoster & incr CPK more common w/ UPA vs ADA/MTX
Abs#1691 #ACR21 @RheumNow https://t.co/tKYi65kB5r
Eric Dein ericdeinmd
3 years 1 month ago
#ACR21 Abs#1677. Effects of bDMARD on Lipids:
⬆️ HDL from 62 -> 66 in 1yr (p=0.013)
❌ No signif change in LDL or LDL-C/HDL-C ratios
@Rheumnow
https://t.co/uMsXKwwqvW https://t.co/fhCbDoa3px
Eric Dein ericdeinmd
3 years 1 month ago
#ACR21 Ab#1681: ATI-450- MK2 Inhibitor
⭐️Downstream MK2 mediated inflamm drive of p38.
⭐️Hope this would avoid tachyphylaxis in p38 inhibitor meds
▶️Phase2a study in 19 pts: Well-tolerated (SEs: UTI, ventricular extrasystole), good 12 week data
@Rheumnow https://t.co/6lo7zPJUpx
Mrinalini Dey DrMiniDey
3 years 1 month ago
Watch my video summary of abstracts #0380 and #0381 presented at the #ACR21 on #SickLeave and #WorkDisability in #axSpA by @ElenaNikiUK and colleagues.
@RheumNow https://t.co/HWEyPoPJi0
Mrinalini Dey DrMiniDey
3 years 1 month ago
SELECT-EARLY results for #upadacitinib in #RA
👉🏼UPA better than MTX for clinical response and remission
👉🏼⬆️rates of HZ, neutropenia, CPK elevations
👉🏼No new safety risks identified
Abs#1692 #ACR21 @RheumNow
https://t.co/wJy7MK4pyF https://t.co/YNpE1Axiw0
sheila RHEUMarampa
3 years 1 month ago
For Dr @LianneGensler managing axSpA requires a sundae🍨approach! How cool is that?!😎
This means that we need to take a holistic approach on the management of axSpA - both non/pharmacologic & there's no one magic pill to treat the disease.
@RheumNow #ACR21 #RheumTwitter https://t.co/o0OjcEn16b
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