LiSa ◡̈︎ rheumarhyme
3 years 2 months ago
#ACR21 #IgG4 Q&A [Drs Stone/Perugino]
📌܄Igg4 in the blood/tissue is NOT diagnostic bec it can also be seen in others (malignancy..etc)
📌its more the presentation/ organ involvement see acr/eular guide: https://t.co/xBvu4r0TM3 https://t.co/WkiF6KyxGq
Pedro Castillo _Castillo_Pedro
3 years 2 months ago
Upadacitinib 56-wk efficacy/safety (mod to severe PsA)
🔹Comparable or ⬆️efficacy vs adalimumab
🔹Efficacy maintained, and 15mg vs 30mg doses similar at 56wks
🔹No new safety findings @ 56wks
🔹🚫inc risk VTE, MACE, cancer vs ada
https://t.co/NlKvBrwDxB
#ACR21 Abst#1345 @RheumNow
Pedro Castillo _Castillo_Pedro
3 years 2 months ago
Echos in PsA, RA:
🔹Diastolic dysfxn: 52% of PsA and RA (!), controls 5%
🔹Mitral regurge PsA 84%, Ra 53%, controls 10%
🔹Mild pulmonary valve regurge higher in PsA
(Diastolic dysfxn has been seen in prior RA studies)
https://t.co/QCKR5itfYj
#ACR21 Abst1308 @RheumNow
Pedro Castillo _Castillo_Pedro
3 years 2 months ago
Supporting date for Ixekizumab in PsA with symptoms of axial involvement.
🔹Improvement in QoL (SF-36), ASDAS, BASDAI50
🔹Maintained at 52 weeks
🔹Stricter criteria (younger, ⬆️CRP) showed similar results
https://t.co/QSJLQTxLcW
#ACR21 Abst#3147
@RheumNow
Eduardo Valdés-Hevia 🦟 Valdevia_Art
3 years 2 months ago
Calcium hyperproficiency is a rare complication of vitamin D deficiency, where excess calcium from bone resorption forms complex structures resembling primary teeth.
Neoformed teeth grow on different bones, such as this patient's hand, causing fractures and joint dysfunction. https://t.co/oGYCYkh1WD
Sheila Angeles-Han STHanMD
3 years 2 months ago
Adults with #JIA #uveitis are still affected into adulthood. @Mara_Becker discusses visual outcomes #ACR21 https://t.co/ZBjw1CfSmv
Kazuki Yoshida kaz_yos
3 years 2 months ago
#ACR21 L06 Comparative Safety of Gout "Treat-to-target" and "Usual Care" Treatment Strategies on Cardiovascular Outcomes Using Observational Data: Causal Inference Approach https://t.co/4qo49lpBrt Video interview (https://t.co/k8PHCPaF1r) https://t.co/D4G2Ylkelm
Mithu Maheswaranathan, MD MithuRheum
3 years 2 months ago
🆕 Updated 2021 ACR Guidance for Adjusting Immunomodulatory Therapy with the COVID-19 Vaccine in Patients with Rheumatic & MSK Diseases
Discussed at #ACR21 COVID-19 Hub!
V4 Link: https://t.co/1SOR9yTQyF https://t.co/PKFKXpLofN
sheila RHEUMarampa
3 years 2 months ago
Prof. Cornelia Weyand wonderfully summarizes the mechanisms behind the premature immune #aging phenotype in #RheumatoidArthritis leading to tissue #Inflammation
🔸defect in mitoDNA repair
🔸expanded rough ER
🔸⬇ protein myristoylation
@RheumNow #ACR21 #RheumTwitter https://t.co/8cyqLscctB
Janet Pope Janetbirdope
3 years 2 months ago
Can you stop monitoring eyes in + ANA and/or pauciarticular pt who becomes an adult if no uveitis ever, in last 5 yrs, etc. When can we stop looking? #AVR21 @RheumNow https://t.co/1Ml1BuJD7Y
Dr. Rachel Tate uptoTate
3 years 2 months ago
Telemedicine for AID patients! A fortunate pandemic outcome that PCPs shared "local" care benefit of specialists for these patients due to telemed. Abs 1062 #ACR21 @RheumNow #RheumNow https://t.co/zb0kZbzxsK
David Liew drdavidliew
3 years 2 months ago
Very high serum IgG4 does not equal IgG4-related disease.
Most of the time (3/4 in this sample), IgG4>5xULN is IgG4-RD.
Some of the time, it's not. (Could be a long list of things)
Criteria are useful
High serum IgG4 alone isn't enough
@zach_wallace_md #ACR21 ABST1103 @RheumNow https://t.co/oxMgnnpIce
sheila RHEUMarampa
3 years 2 months ago
Did you know?🤔Immune #aging:
🔖Begins at 20y and accelerates at 50y
🔖Species-specific
🔖The older immune system is restructured (keep that in mind when diagnosing or treating these pts)
🔖Accelerated w/ chemotx, chronic infection etc.
@RheumNow #ACR21 https://t.co/bgbN3VKMCw
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 2 months ago
#ACR21 Year in Review. Caielli et al. showed in some patients with #lupus, red blood cells retained their mitochondria (Mito+ RBCs) and their frequency correlated with disease activity and blood⬆️IFN @RheumNow https://t.co/ZixgAbOWJ0 https://t.co/hkTWE4m7Ph
Md Yuzaiful Md Yusof Yuz6Yusof
3 years 2 months ago
#ACR21 Year In Review highlighted the need to combat the root causes of socioeconomic disparities to improve functional status in #rheumatoid #arthritis @RheumNow https://t.co/MKgh7UEP8b https://t.co/Vg2jyfuDnf