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TheDaoIndex KDAO2011
3 years 2 months ago
Dr. Chambers reviewed @MotherToBaby data of pregnant rheum women during the pandemic noted:
⬆️EtOH use in pregnancy,
⬆️stress, anxiety, depression
⬆️obesity
⬇️likelihood to get prenatal care
#ACR21 @rheumnow #RheumPregnancy https://t.co/GCYCIuiunS
TheDaoIndex KDAO2011
3 years 2 months ago
#GreatDebate: add on BLMB vs. VCS to MMF for LN
Dr. Petri argues for BLMB b/c:
👉cost is less
👉better adherance
👉not good for class V
👉voclosporin had greater nephrotoxicity
👉insuff data in pregnancy, but not contraindicated like VSC #ACR21 @rheumnow https://t.co/mk2eXwkxcG
TheDaoIndex KDAO2011
3 years 2 months ago
#ACR21 #GreatDebate: Dr. Rovin argues for VCS add to MMF b/c:
👉fewer side effects than legacy CNI
👉elevated in creatinine related hemodynamic reversible effect
👉did increase BP (but controllable)
@rheumnow (2/2) https://t.co/mmWp0sBveT
Aurelie Najm AurelieRheumo
3 years 2 months ago
💻 Telemedicine: would you rather have a telephone or a video clinics? Non inferiority RCT shows 80% satisfaction rates and phone-only non-inferior to video visits. I would have expected patients to prefer video visits 🧐 #ACR21 #Abst0112
@RheumNow https://t.co/klgMJ6EthH https://t.co/17ffTAZCfv
Aurelie Najm AurelieRheumo
3 years 2 months ago
Data science for the dumbs. Very informative talk from Dr Jamie Collins! Surely helpful for me. A good way to decide on the best supervised methods for data analysis in machine learning is to separate according to our goal: to explain or to predict? #ACR2021 @RheumNow https://t.co/J0j6VMkoTV
Aurelie Najm AurelieRheumo
3 years 2 months ago
Don't forget to discuss Influenza vaccination w/ your RA patients! Higher concerns about RA medications and low necessity of vaccination beliefs associated with a ⬇️ likelihood of vaccination and suboptimal vaccine coverage.
#ACR21 @RheumNow #Abst0141 https://t.co/c5GthZxh3n https://t.co/4Nt92CHFzV
Aurelie Najm AurelieRheumo
3 years 2 months ago
Our Panel discussion on highlights of #ACR21 Day1 held live yesterday with great colleagues from @RheumNow faculty is now available online! 👯♀️ @RichardPAConway
@Yuz6Yusof @bella_metha @_Castillo_Pedro https://t.co/ulZTNNeqKf
Eric Dein ericdeinmd
3 years 2 months ago
Abst#271 #ACR21. RA activity predicts left ventricular mass change in pts without CVD
⭐️35% had abnormal LV geometry at baseline TTE
⭐️55% at f/u TTE 3-6 years later
⭐️Increase in concentric remodeling on LV
@Rheumnow https://t.co/uHnqITcTy9 https://t.co/KmV8volVwd
Eric Dein ericdeinmd
3 years 2 months ago
#ACR21 Abst#0276:
Pulse pressure (PP) = Systolic BP - Diastolic BP, measures arterial compliance
⭐️RA: higher PP than controls
⭐️PP was independent risk factor for subclinical atherosclerosis
▶️ Look at the vitals, we have this at every pt visit!
@Rheumnow https://t.co/KZaf1AwO6Q https://t.co/kN4xGxWiV9
Eric Dein ericdeinmd
3 years 2 months ago
Before the Great Debate:
Next step for Lupus Nephritis?
#ACR21 @Rheumnow
Eric Dein ericdeinmd
3 years 2 months ago
#ACR21 Great Debate: Voclosporin vs Tacro?
⭐️Voclosporin has carbon bond extension, changing how voclosporin binds to calcineurin.
⭐️Consistent dose-response prevents need for drug monitoring
⭐️Increases potency and results in improved metabolic profile
@Rheumnow https://t.co/cY93st7754
Eric Dein ericdeinmd
3 years 2 months ago
Dr. Rovin at #ACR21 Great Debate:
▶️ Disagrees with Dr. Petri that GFR changes are caused by hemodynamics and is temporary, and non-nephrotoxic
▶️ Voclosporin + MMF is safe
@Rheumnow https://t.co/TxDyprnZ5u
Eric Dein ericdeinmd
3 years 2 months ago
Personalize decision points in belimumab vs voclosporin @jhrheumatology Dr. Petri
▶️ What is the outcome you are most interested in? GFR?
▶️ Is there extra-renal lupus
▶️ Infection risk
⭐️Ultimately, need biomarkers to know who will respond the best
@Rheumnow #ACR21 Great Debate
Eric Dein ericdeinmd
3 years 2 months ago
Enjoyed the @Rheumnow daily panel - #ACR21 day 3 is in the books!
https://t.co/Wp48PHRCHn
Bella Mehta bella_mehta
3 years 2 months ago
VEXAS plenary abst#1426 #ACR21 83 patients
🎙️vast majority mutations in p.MET41
Worse mortality when:-
▶️valine mutations on p.MET41
▶️ear chondritis
▶️being transfusion dependent https://t.co/qnA2lPn5yR
Poster Hall