Akhil Sood MD AkhilSoodMD
4 years ago
Abstr 1044
Anastasiou & colleagues examined Rx of inappropriate medications in elderly patients with rheumatic disease (RD)
- 40% RD patients received inappropriate meds
- Elderly living in areas of low SES likely to receive opioid Rx
#ACR21 @RheumNow #BeersCriteria https://t.co/fxBGVAtt1L
Md Yuzaiful Md Yusof Yuz6Yusof
4 years ago
#ACR21 #Abstr1426 VEXAS is only recently described but a study in 83 patients showed importance of genotyping + clinical in predicting mortality:
💠p.Met41Val (OR: 2.6)
💠Transfusion dependent (4.5)
💠Ear chondritis protective (0.3)
@RheumNow #ACRBest https://t.co/RQwONf2MJT https://t.co/VLWRGKWmQs
David Liew drdavidliew
4 years ago
The VEXAS story developing and becoming clearer...
with high mortality genotype-phenotype linked
genotype at risk for mortality (p.Met41Val)
- smaller residual UBA1b expression
- less RP
- more fever
wonderful from @maferradastrong
#ACR21 ABST1426 @RheumNow @RP_Organization https://t.co/vELXprUrPh
Robert B Chao, MD doctorRBC
4 years ago
Voclosporin for lupus nephritis maintained reductions in proteinuria. No change in eGFR at 30 months of treatment
(AURORA 2 study)
Abs#1425
#ACR21
@RheumNow https://t.co/1y9oSVXzD8
Eric Dein ericdeinmd
4 years ago
#ACR21 Abs#1427- Statin Use in RA
⭐️# needed to treat: 42 pts all-cause mortality
⭐️NNT 102 pts CVD events
⭐️# needed to harm: 127 pts T2DM (mild ⬆️ risk)
▶️Statin use: mortality benefit better than gen pop, CVD&DM similar effects to gen pop
@Rheumnow https://t.co/m5bl9Ho163 https://t.co/hijxbcVBzA
David Liew drdavidliew
4 years ago
I've written more about these really useful data here for @RheumNow:
https://t.co/3dQteFr9qZ
#ACR21 @earlyarthritis @BykerkVivian https://t.co/7HufoWVtCK
Pedro Castillo _Castillo_Pedro
4 years ago
AURORA 2 (A2): SLE + LN
AURORA 1: Adding Voclosporin to MMF + Steroids ⬆️complete renal response by 18% @ 52w
A2: @ 30 months
💠Maintained mean GFR
💠Maintained reductions in proteinuria
💠Further safety/efficacy data to follow
https://t.co/wSvQvueKi7
#ACR2021 Abst#1425 @RheumNow
TheDaoIndex KDAO2011
4 years ago
Median survival for pts w/#VEXAS➡️10 years
Predictors of mortality w/VEXAS:
👉p.MetVal mutation HR 3.5 (95%CI, 1.4-8.5)
👉transfusion dependency HR 2.59 (95%CI, 0.94-7.09)
👉⬇️risk w/ear chondritis HR 0.26 (95%CI,0.09-0.6)
@marcelaferrada #ACR21 @rheumnow Abstr#1426 #ACRbest
Dr. John Cush RheumNow
4 years ago
Plenary on VEXAS - good over view of VEXAS and why important to Rheums #ACR21 Abstract# 1426 https://t.co/jx0mQNlfwK
Dr. John Cush RheumNow
4 years ago
SLE Panel: Learning about Lupus at #ACR21
Drs. Kathryn Dao ( @KDAO2011) , Janet Pope ( @Janetbirdope) Yuz Yusof ( @Yuz6Yusof) Bella Mehta ( @bella_mehta) and Pedro Castillo ( @_Castillo_Pedro) discuss lupus-related data presented Saturday.
https://t.co/h0vPIwUeOz https://t.co/eJDtRKPdYT
Meral K. El Ramahi, MD MeralElRamahiMD
4 years ago
Clinical Pearl from Dr. @JKolfenbach
"Sometimes, taking off the mask is worth it" during physical exam:
➡️Strawberry gums in GPA
➡️Drug-induced gingival hyperplasia
‣ i.e. cyclosporine, CCB
➡️Tongue necrosis in GCA
➡️Ovoidal palatal patch in TIF1gamma DM
#ACR21 @RheumNow https://t.co/H98bTLLse6
Meral K. El Ramahi, MD MeralElRamahiMD
4 years ago
Wonderful overview of myositis autoantibodies to reference from the Rheum Secrets & Pearls session by Dr. @JKolfenbach & Dr. John Stone at #ACR21 that can be accessed on-demand now!
@RheumNow https://t.co/H6N02MzFSu
Md Yuzaiful Md Yusof Yuz6Yusof
4 years ago
#ACR21 #Abstr1423 Munroe & James developed a novel #Lupus Classification Risk Immune Index using either 9 or 32 soluble mediators from sera. This index could predict transition to meeting classification criteria (with or without autoantibodies) @RheumNow https://t.co/Kr9fWaoW1L https://t.co/8wkgrzeRnt
Dr. Rachel Tate uptoTate
4 years ago
Spanish study finds OP is more frequent in male PsA pts, assoc'd w/age independent of dz hx. Femoral OP more frequent in pts w/ axial involvement, HTN, heart ischemic disease & vitamin D deficiency. Abs 1325 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/A3v6ZHZnN8 https://t.co/2jfAOSuLtK
Bella Mehta bella_mehta
4 years ago
We @HSpecialSurgery previously demonstrated improved fetal mortality in #lupus in @AnnalsofIM
Racial disparities persist ~61K #lupus pregnancies - 10 yr US national data #abst1034 at #ACR21 more reduction in Asians and Hispanics than African Americans @RheumNow https://t.co/KeO0FdMB7f


Poster Hall