Mrinalini Dey DrMiniDey
4 years ago
Is #calprotectin the new ESR/CRP?
👉🏼SLR finds calprotectin correlates w/ ultrasound synovitis in RA
👉🏼In some studies, it was a better biomarker than ESR/CRP
👉🏼It can distinguish ultrasound remission from subclinical synovitis
Abs#1207 #ACR21 @RheumNow
https://t.co/ADkRBq5KoG
Aurelie Najm AurelieRheumo
4 years ago
CATCH cohort: PT CDAI and MD CDAI correlate good to strongly at 3 and 6mo in patients with no non articular pain or w/regional pain but 🚨 NOT in pts w/ widespread pain! We should find alternative remote DA measures for this pop. #ACR21 @RheumNow #Abst1202 https://t.co/LsCtsfXsN1 https://t.co/gjeGxBA0HB
Mrinalini Dey DrMiniDey
4 years ago
My video summary on this important piece of work by @Sineadm15 is now available to watch on @RheumNow:
https://t.co/Gh64D4PADw
#ACR21 #MentalHealth #Depression #AxSpA https://t.co/EcH4VDs2Xi
Eric Dein ericdeinmd
4 years ago
#ACR21 Abs#1196: Morning stiffness (MS) in pre-RA arthralgia associates w inflammation
⭐️Arthralgia pts: 14% ACPA+, 34% w MS
MS correlates w ⬆️subclinical synovitis/tenosynovitis on MRI and higher CRP. Duration of morning stiffness correlates
https://t.co/DUhgjbjQIr
@Rheumnow https://t.co/dHl7LuY3ZA
In a world where telemedicine and virtual care are not going away, is there value in patients assessing their own tender and swollen joints?
Work from the Canadian Early Arthritis Cohort (CATCH, @earlyarthritis) presented by Dr. Vivian Bykerk (@BykerkVivian) is the subject of two abstracts from Monday’s poster floor, exploring the utility as to how patient assessments might match up to rheumatologist assessments.
Mrinalini Dey DrMiniDey
4 years ago
We need to be better at identifying and managing #depression in patients with #axspa.
In a group of 70 pts, many had high HADs-D & PHQ-9, with worse disease activity & #QoL compared to those with normal scores.
Abs#1305 #ACR21 @RheumNow
https://t.co/lNoo0HfMcC https://t.co/n7Vyl9L5FR
Aurelie Najm AurelieRheumo
4 years ago
Ultrasound in CSA patients:
Retro US cohort 110pts
28.2% w/ 💥Power Doppler synovitis. 36.8% at 6mo evolved to RA among which 100% PD+ vs 25% PD-
PD + predicts evolution to clinical RA (OR 13.1; CI 1.07-161.04)
Easier and less invasive than MRI!
#Abstr1525 #ACR21 @RheumNow https://t.co/MkhWTvnv3L
David Liew drdavidliew
4 years ago
TCZ in GCA: one disadvantage is that you can't use CRP+/- ESR for flares
Mavrilimumab in GCA:
- CRP/ESR consistently go up with symptomatic flares
- CRP/ESR up less (cf. placebo), in the absence of Sx flares
More signal, less noise.
phase 2 post-hoc #ACR21 ABST1401 @RheumNow https://t.co/c0lMJMcQv0
Dr. John Cush RheumNow
4 years ago
Watch: Lupus Updates: Dr. Michelle Petri
Dr. Michelle Petri offers perspective and insight into lupus related data presented Saturday at the #ACR21 annual meeting.
https://t.co/L7T2mNJVH0 https://t.co/MCQ7nJjCIY
Md Yuzaiful Md Yusof Yuz6Yusof
4 years ago
#ACR21 #Abstr1100 Pulmonary Hypertension is a rare complication of AOSD. What can we learn from case-series of N=13🧐 💠All were female 💠Severe at diagnosis: mean PAP 41mmHg; 85% had NYHA III&IV 💠38.5% mortality rate So, plz be aware of PAH @RheumNow https://t.co/gmXF3AzH2n https://t.co/s5CXrHYUor
David Liew drdavidliew
4 years ago
Atypical patterns of HCQ retinopathy:
- outside the central macula
- missed by standard central macula screening
- 41x more likely in Asians!
Lesson: screening with extramacular SD-OCT for Asian HCQ pts is so, so important. 41x over.
@MGHrheumatology #ACR21 ABST0989 @RheumNow https://t.co/0w7ALHJDSW
Md Yuzaiful Md Yusof Yuz6Yusof
4 years ago
#ACR21 #Abstr1083 Do pts with Autoinflammatory disease flare differently during #COVID19? Survey of N=647 (mostly CAPS):
💠56% No change
💠Of pts who flared, 50% had low/absent fever
💠7% had COVID; mostly mild
Shielding could influence results @RheumNow https://t.co/g7VazLfiT9 https://t.co/lzaSoMEzyR
Md Yuzaiful Md Yusof Yuz6Yusof
4 years ago
#ACR21 #Abstr1011 Can we differentiate NEMO-deleted exon 5 autoinflammatory syndrome (NEMO-NDAS) vs CANDLE? Bioinformatics to mask the IKBKG pseudogene is promising and identified IL-6, 8,18, IFN-I and TNF-induced cell death as future targets @RheumNow https://t.co/tR2PNymMVn https://t.co/yCKHQx6R3E


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