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Catherine Sims, MD DrCassySims
2 years 5 months ago
Preterm delivery and HTN disorders in #vasculitis
Abstract #0953 #ACR22 @RheumNow @StanfordRheum
🤰87 deliveries from 1991-2012
🤰Higher risk for preterm delivery (PTD) (RR 4), PPROM (RR 4), HTN dx of preg. (RR 3)
🤰Of spon. PTD, 17% born between 20-31 weeks
Dr. John Cush RheumNow
2 years 5 months ago
Can Neural Networks Answer Important Diagnostic Dilemmas in Rheumatology? #ACR22
https://t.co/TThsEQ7RDH https://t.co/ZHNlH3J0de
Eric Dein ericdeinmd
2 years 5 months ago
Ab1676 #ACR22 SAPHYR: Sarilumab in Refractory PMR
52wk SAR 200 mg q2w + 14w taper GC v PBO+GC taper
Primary endpt: sustain response at 52w
Early term 2/2 COVID, 117 pt
SAR remission 28% vs PBO 10%, p=0.02
Data consistent when removes CRP data
PBO: more GCs 2/2 PMR flare
@Rheumnow https://t.co/kHq3juULX1
David Liew drdavidliew
2 years 5 months ago
How much does diet and exercise help in knee osteoarthritis?
Pragmatic RCT (WE-CAN), n=823
a diet & exercise intervention program led to:
- 10kg weight loss
- some significant pain improvements
We need to fund diet & exercise programs for OA patients!
ABST1675 #ACR22 @RheumNow https://t.co/Ctm8ZoRF3o
Dr. Antoni Chan synovialjoints
2 years 5 months ago
Update on ACR Guideline on Prevention and Treatment of GIOP.
Sequential Rx when initial OP Rx and GC discontinued
https://t.co/TWdI728pCp
Mary Beth Humphrey #ACR22 @RheumNow https://t.co/i320si4RJp
Julian Segan JulianSegan
2 years 5 months ago
Sarilumab (IL-6R inhibitor) in phase 3 trial for relapsing PMR (SAPHYR trial).
Key inclusion: Disease flare while taking >7.5mg prednisolone
Sustained remission: resolution of symptoms, normalisation of CRP, adherence to prednisolone taper
@RheumNow #ACR22 #Plenary
Richard Conway RichardPAConway
2 years 5 months ago
Spiera et al. Sarilumab in refractory PMR (SAPHYR) - Phase 3 RCT. Significant effect of IL-6i. @RheumNow #ACR22 Abstr#1676 https://t.co/2MS441B8gU https://t.co/jBd7YJKrTs
Janet Pope Janetbirdope
2 years 5 months ago
#ACR highlights - #pegloticase in #gout - less reactions and more benefit w #MTX MIRROR RCT. Better than no MTX. Will change my practice - if I can access to a #peguricase, I will Rx w concomitant MTX Abst#0001 #ACR22 @RheumNow
Dr. Antoni Chan synovialjoints
2 years 5 months ago
Updated ACR Guidelines on Prevention and Rx of GIOP
Rx recommendations when new fractures occur after 12 months of initial OP Rx
https://t.co/TWdI728pCp
Mary Beth Humphrey #ACR22 @RheumNow https://t.co/wHANvymd5R
Dr. Antoni Chan synovialjoints
2 years 5 months ago
Updated ACR Guidelines on Prevention and Rx of GIOP
OP Rx in special populations
https://t.co/TWdI728XrX
Mary Beth Humphrey #ACR22 @RheumNow https://t.co/0h72a4jXmG
Aurelie Najm AurelieRheumo
2 years 5 months ago
PATCH study, 👁 safety data in children 5 yrs after birth
In utero HCQ exposure does NOT:
-impact retinal morphology (OCT)
-reduce significantly retinal thickness
https://t.co/D7SgPG6PX4
Abs#1647 #ACR22 @RheumNow
sheila RHEUMarampa
2 years 5 months ago
WE-CAN pragmatic RCT on community-dwelling ♂️&♀️ >/=50y w/ knee #osteoarthritis & obesity:
💠Diet + exercise = significant weight ⬇️and ☑️WOMAC pain score, WOMAC function, 6min walk distance & SF-36 HRQoL
🍽️+🚶♀️in OA? = Yes we can!
#ACR22 @RheumNow @rheumarhyme https://t.co/Ty2boH52HC
Eric Dein ericdeinmd
2 years 5 months ago
Ab1675 #ACR22 WE-CAN - Knee OA
823 randomized pts, 18 mo: Intensive Diet & Exercise (D+E)
Primary endpt: WOMAC pain - 32% reduct in pain in D+E, vs 24% (PBO)
20% more likely: clinically meaningful improve
Improved BMI, 6MW, HRQoL, activity
Pain Rx, depression: no change
@RheumNow https://t.co/Su2g4Z38FV
Janet Pope Janetbirdope
2 years 5 months ago
Does diet & exercise work for knee pain in #osteoarthritis? Pragmatic trial in 3 community sites. 823 RCT, 80% completed -control was education &meetings vs diet&exercise;more intense. 101kg, 77% F, age 65. Diff modest-favoured diet & exercise-works a bit #ACR22 @RheumNow #1675 https://t.co/akjEjVprJl
sheila RHEUMarampa
2 years 5 months ago
Pain in #psoriaticarthritis might not be all inflammatory..
In this study presented by Dr F Sunzini:
👉PsA pts w/⬆️FM scores had⬆️functional brain connectivity bet mid-post IC & thalamus, phgyrus & PFC
..so consider nociplastic pain too & adjust mgt
#ACR22 @RheumNow ABST#2256 https://t.co/suCAvx0pD5
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