ASAS definition of Difficult-to-Manage Axial Spondyloarthritis (D2M axSpA) with criteria including treatment failure, suboptimal control, and persistent problematic symptoms. 89% of ASAS members endorsed the definition, including treatment-refractory cases with specific… https://t.co/3qWPQAGZ7c https://t.co/mVQzfLtaiI

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The 2009 ASAS classification criteria did not meet the set targets of 75% sensitivity and 90% specificity in the CLASSIC cohort, indicating the need for revision of these criteria to increase its performance and validity in classification of axSpA. Abst#0820 #ACR24 #ACRBest… https://t.co/lF3QbRUpx3 https://t.co/SHPMpCjizS

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Gender based response in Axial SpA. A hot topic at ACR @ACRheum @RheumNow @hac28 @SPARTAN_Updates https://t.co/zbnE6kjQhL

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Ab#0458 #ACR24 10 year outcomes of 176 patients with seroneg RA 32 pts (18%) had change in dx - SpA (11), seropos RA (6), OA (5), crystal (3), CTD (3), Ifn-related/paraneopl/RS3PE, sarcoid (1) 40 (23%) had drug-free remission 30 (17%) started b/tsDMARD @RheumNow

Gender differences in axSpA extend to dse activity assessment tools. PREDICT-SpA: 🔶️BASDAI score performed better in women. 🔶️ ASDAS-CRP homogenous performance on both genders. Consider BASDAI for assessing dse activity in women? @RheumNow #ACR24 abs571 @rheumarhyme https://t.co/rKJXn2EPXa

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A study from the EuroSpA collaboration validates new BASDAI cut-offs for disease activity in axial spondyloarthritis based in ASDAS: <1.4 for remission, <2.8 for low activity, and >5.9 for very high activity. This research enhances our understanding of disease states and their… https://t.co/OkPiTwSHz6 https://t.co/NjIDeme9dm

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A 6-year study of the link between alcohol consumption and spinal radiographic progression in axial spondyloarthritis (axSpA). Results indicate that alcohol may worsen spinal damage, particularly in males and those with radiographic axSpA. Future research should explore… https://t.co/IIvTyq7kBe

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Using #MachineLearning for predicting flares in axSpA @DiegoBenavent et al, data from METEOR-SpA registry showed the ff predictors of flares thru the reduced logistic regression model: 🔅lower ASDAS 🔅enthesitis 🔅prior flares 🔅longer treatment duration @RheumNow #ACR24 abs559 https://t.co/wyIo9gnKVJ

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Characteristics of difficult-to-treat AS accdg to a retrospective study by @DaoudAnsaam @mmagrey1 et al ⬆️ BMI + comorbidities: HTN, CKD, depression + EAMs: IBD, Pso, iridocyclitis + HLA-B27 Interesting real world data. @RheumNow #ACR24 abs573 https://t.co/GlE4tFpsSz

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Data from the study by Dr. Aguilar et al showed that high dose NSAID use was not assoc'd with incident HTN in their cohort of early axSpA patients. Shows important role of NSAIDs in #axSpA but still should be used judiciously @RheumNow #ACR24 abs540 @rheum_cat @rheumarhyme https://t.co/LK5yFZynu4

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Switching vs cycling - which is better? In PsA & axSpA, a real-world analysis shows that switching to IL-17Ai after TNFi discontinuation may lead to similar or better outcomes compared to cycling to another TNFi. Data from the CorEvitas PsA/SpA Registry. Abstr#0585.… https://t.co/AJP4NBjmzr

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The risk of discontinuing first line biologics was twice higher in non-radiographic female patients compared to males. Abstr#0572 @RheumNow #ACR24 https://t.co/1tQUhsbqUu

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Data from the French DESIR cohort reveals no significant link between high-dose NSAID use and incident hypertension in patients with axial spondyloarthritis. Two thirds were high dose NSAID users at baseline. Incident hypertension occurred in 11% individuals during follow-up.… https://t.co/EAICDwzxNT

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