Mitochondria: the powerhouse of the cell—but the fuel behind gout flares? #ACR24 @RheumNow https://t.co/lV4dovLV18

• https://twitter.com/tuhina_neogi/status/1858614167109816655

Wang et al. Propensity score matched cohort study. 63,302 individuals. Colchicine associated lower risk of THR/TKR, HR 0.87. @RheumNow #ACR24 Abstr#2557 https://t.co/UUU3Tm67ML https://t.co/uKi0e8E7HV

• The Relation of Colchicine to Knee/hip Replacement Among People with Gout in a …
• https://x.com/RichardPAConway/status/1858572127508877503/photo/1

#Gout attack is assoc w 1.5 X MI, MACE in next 30 days @ACRheum @RheumNow #ACR24 https://t.co/7IeFbW6xW8

• https://twitter.com/nellziade/status/1858212544118222855

This is very true. We showed a number of years ago that patients with gout have increased platelet activation at baseline, which then dramatically increases during flare. Treating gout properly may ameliorate this. #ACR24 @RheumNow https://t.co/VL8fy3ezjx https://t.co/9XdrG1NG9c

• Increased platelet reactivity as measured by plasma glycoprotein VI in gout
• https://twitter.com/RoxOsler/status/1857776584112890292

Challener et al. TriNetX study. 32,000 patients. SGLT2i reduce need for gout visits (HR 0.94) ULT initiation (HR 0.69) and colchicine (HR 0.82). I worry about the discordant rates, ULT initiation much lower. @RheumNow #ACR24 Abstr#0848 https://t.co/VTKHMmDEKV https://t.co/C2opiDmBXx

• Impact of SGLT2i Initiation on the Need for Urate-Lowering Therapy and Colchici…
• https://x.com/RichardPAConway/status/1857896424786243864/photo/1

📈 Data from @UIowa_Rheum on how rurality impacts delay to diagnosis in #GCA 📍 0747 👉🏼 People living in more rural areas have an increased time to diagnosis & treatment- further prospective studies needed to delineate effects of rurality further @RheumNow #ACR24 @LemonReneeNi https://t.co/3YMcI9ha3T

• https://x.com/DrMiniDey/status/1857830313071677758/photo/1

Yokose et al. Population study using NHANES. Gout patients had 1.6 higher fold risk of gallstone disease. What? Why do we care? Well, GLP-1s associated with higher risk gallstones also... @RheumNow #ACR24 Abstr#0133 https://t.co/nf4R0hQe50 https://t.co/wDrEDeNbpT

• The Association Between Gout and Gallstone Disease: US General Population Analy…
• https://x.com/RichardPAConway/status/1857824198754029764/photo/1

#ACR24 Year in Review: 💡GLP1i significantly decreased knee OA pain over time (or was it the wt loss itself?🤨) 💡CD19 CAR T-Cell therapy has potential to treat/cure many autoimmune diseases (are risks and $ worth the benefit?) 💡 High risk of CV events within 30 days of gout… https://t.co/XF63zr6lk4 https://t.co/oRNri66Il9

• https://x.com/i/web/status/1857779533933396132
• https://x.com/AdelaCastro222/status/1857779533933396132/photo/1
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• https://x.com/AdelaCastro222/status/1857779533933396132/photo/1