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Lupus

      Prevalence of HLH among pts w/SLE: lower than consults would suggest!

      Observational study using NIS: 139 cases out of
      5 months ago
      Prevalence of HLH among pts w/SLE: lower than consults would suggest! Observational study using NIS: 139 cases out of >100k pts w/SLE (0.13%); 6 fold increase in mortality Fits my priors; HLH is overdiagnosed, but bad when it happens @RheumNow #ACR24 Abstr#0619 https://t.co/iz3BlUOJb9
      #Abstract0649
      Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing inc
      5 months ago
      #Abstract0649 Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing incident LN from SLE, treated LN & healthy controls. @RheumNow #ACR24 https://t.co/aCRzt9TtoK
      Another abstract #0650 highlighting the impact of tubulointerstitial inflammation predicting risk of CKD/ESRD in lupus n
      5 months ago
      Another abstract #0650 highlighting the impact of tubulointerstitial inflammation predicting risk of CKD/ESRD in lupus nephritis @RheumNow #ACR24 https://t.co/XYwO0xnWNR
      Discrimination in #SLE is a chronic stressor - Asians had substantial levels along with association of worse mental heal
      5 months ago
      Discrimination in #SLE is a chronic stressor - Asians had substantial levels along with association of worse mental health and SLE activity Data from the California Lupus Epidemiology Study (CLUES) using the Everyday Discrimination Scale (EDS) @JYazdany @RheumNow #ACR24 abst#0171
      Cardiology 🤝 Rheumatology
      #Abstract0611 highlights Subclinical atherosclerosis (carotid plaque > 1.5 mm) associat
      5 months ago
      Cardiology 🤝 Rheumatology #Abstract0611 highlights Subclinical atherosclerosis (carotid plaque > 1.5 mm) associated with ↑ risk of CV events in SLE longitudinal cohort @RheumNow #ACR24 https://t.co/jLLYNOfFZ2
      Can PROs help identify high-risk #SLE patients? #Abstract0655 from the FORWARD registry shows higher SLAQ scores (includ
      5 months ago
      Can PROs help identify high-risk #SLE patients? #Abstract0655 from the FORWARD registry shows higher SLAQ scores (including flares) and RDCI are linked to increased hospitalization risk. @RheumNow #ACR24
      Abstr#0647
      Toronto Lupus Clinic finds pericarditis in 20% of #SLE inception cohort, often with skin, heme, MSK, & re
      5 months ago
      Abstr#0647 Toronto Lupus Clinic finds pericarditis in 20% of #SLE inception cohort, often with skin, heme, MSK, & renal involvement. Linked to younger age, White race, +SSB, & lower ACR/EULAR scores - Tx: GC, HCQ, AZA @RheumNow #ACR24
      Abstract #0614
      What is the impact of Lupus on my quality of life?
      Consider using Lupus Impact Tracker (https://t.co/fJQe
      5 months ago
      Abstract #0614 What is the impact of Lupus on my quality of life? Consider using Lupus Impact Tracker (https://t.co/fJQe2uHicM) - high dose GC, comorbidities, and not actively working associated with worse impact on QoL - HCQ shows benefit @RheumNow #ACR24
      Lots of ‘CARTS’, not enough ‘work horses’!

      There are now ~40 CAR-T protocols in #lupus incl many presentations
      5 months ago
      Lots of ‘CARTS’, not enough ‘work horses’! There are now ~40 CAR-T protocols in #lupus incl many presentations at #ACR24 -most are uncontrolled -selection of pts is key. We need a pathway forward for reg approval & guidelines for studies! @RheumNow @ACRheum 18abst #OOO4 https://t.co/Mckwvn3Ffn
      Small but useful open label RCT of MMF vs CYC vs TAC in SLE nephritis

      Surprisingly similar rates of remission at week 2
      5 months ago
      Small but useful open label RCT of MMF vs CYC vs TAC in SLE nephritis Surprisingly similar rates of remission at week 24... suggests TAC could be an option for induction? #ACR24 @RheumNow Abstr#0670 https://t.co/rO0ufturHW
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