Important study in SLE: out of 590 pts with pericarditis, 20% had recurrence w/in 1 year Higher in early dx, younger pts, higher dx activity, & pred exposure Is prednisone risk confounding by indication? Or causative? #ACR24 @RheumNow @andreafava Abstr#2372 https://t.co/Seyi4F6weY

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Depressing finding re:glucocorticoid discontinuation in SLE No improvement over decades in rate of GC discontinuation; if anything, we start more GC than ever @AliDuarteMD help me out here; why haven't we made more progress? #ACR24 @RheumNow Abstr#2421 https://t.co/uzZATKPWVC

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Why is there female predominance in #SLE - the extra X chromosome in females (XX) may not be inactivated properly- usually maintained by the long non-coding RNA #Xist #ACR24 abst#2599 @RheumNow https://t.co/C9Qj5zSnpN

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Updated ACR guidelines on management of lupus nephritis (LN). Consider early biopsy. Focus on triple therapy in LN. From the panel discussion, Tacrolimus can be an alternative to CNI (Voclosporin) where there is no access to this. Manage comorbidities such as CV risk, bone… https://t.co/4R02YnRXDP https://t.co/3J7YcF5ucQ

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Applying the guidelines to Cases- Dr M Dall’Era for a pt wit extrarenal lupus and active LN. #ACR24 @rheumnow https://t.co/lvOUWjEdEz

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The updated 2024 ACR Guideline for Dx and Tx of #lupus nephritis is here! Dr. Lisa Samaritano discusses the key recommendations 👇 For all pts: screen for LN, give HCQ and RAAS for pts with ⬆️ proteinuria GCs in pts w/ LN class III/IV &/or V. @Rheumnow #ACR24 @rheumarhyme https://t.co/wLVRGktR59

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The overview for #lupus nephritis tx. Triple therapy is preferred as first line due to: 1. RCTs (BLISS-LN & AURORA 1) showing improved outcomes w/ triple txs 2. Nephron loss happens with ongoing LN - time is kidney! @RheumNow #ACR24 https://t.co/IQo3q3O1pt

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Recommend "Triple Therapy" = Glucocorticoids + two other agents Practically, that means MMF + belimumumab OR CNI for most pts For the CYC afficionados, the lower-dose EUROLUPUS protocol is preferred #ACR24 @RheumNow https://t.co/0gRISXSw0c

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Applying the #ACR24 #LupusNephritis: Case 2 by Dr M Dall’Era @RheumNow https://t.co/A7i103uHZT

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