Lupus

Bella Mehta bella_mehta
10 months 3 weeks ago
#Disparites posters #ACR24 - Analyzed 954 SLE patients
- Black and Asian patients had higher severe damage events
- Neighborhood disadvantage (ADI) linked to increased severe damage
- Older age and comorbidities increased damage risk
abst#0362 @rhuemnow

Bella Mehta bella_mehta
10 months 3 weeks ago
Disparities posters #ACR24
- Analyzed 10,604 SLE patients
- 18.7% in the lowest SES group experienced functional status decline vs. 12.5% in the highest SES group
- African American patients and Greater neighborhood deprivation did worse
#ACR24 abst#0190
@RheumNow

Bella Mehta bella_mehta
10 months 3 weeks ago
Contraception counselling in #SLE post intervention
- Contraceptive counseling rates improved from 33.9% to 55.7%
- Women over 35 were 4.09 times more likely post-intervention
- Non-Hispanic Black women were less likely than Hispanic women
#ACR24 abst#0184 @RheumNow https://t.co/sOZXnAe4ov


sheila RHEUMarampa
10 months 3 weeks ago
High serum BAFF as a novel RF for dev't of preeclampsia in pregnant SLE pts?
This study by Dr. C Sims et al showed that SLE pregnancies w/preeclampsia had significantly higher BAFF levels during the 1st trimester, and likely w/ ⬆️dsDNA or ⬇️ complement
@RheumNow #ACR24 abs424 https://t.co/kNzyuT03r2


Gabriela Martinez Zayas, MD MartinezZayasMd
10 months 3 weeks ago
This interesting systematic review showed that the prevalence of ILD was 15% in patients with SLE. This higher than previously reported! #ACR24 @RheumNow https://t.co/O1aZUUL4Ho


Bella Mehta bella_mehta
10 months 3 weeks ago
Researchers developed a digital messaging program to reduce fatigue in SLE
- Grounded in social cognitive and self-determination theories
- Reviewed 148 messages, refined based on patient feedback
- High patient ratings, future will see more of these #ACR24 abst#0362 @RheumNow

Eric Dein ericdeinmd
10 months 3 weeks ago
Ab#0427 #ACR24
HSS: menopause & systemic rheum disease severity
1/3 women report worse disease associated w menopause
Reported more flares, menopausal symptoms
Findings were similar between SLE and RA, but SLE patients were >2x more likely to discuss w their rheum
@RheumNow

Bella Mehta bella_mehta
10 months 3 weeks ago
#ACR24 abst#0430
- Analyzed 61 SLE pregnancies
- Higher early gestational Mean Arterial Pressure before 20 Weeks linked to increased preeclampsia risk
- MAP trends at 8-10 and 17-19 weeks showed highest predictive accuracy for risk prediction
@RheumNow https://t.co/37mg0WX43v


Bella Mehta bella_mehta
10 months 3 weeks ago
FDA recently approved - fms-like tyrosine kinase 1 (s-Flt1) / placental growth factor (PlGF), for diagnosing preeclampsia.
sFlt1:PlGF≤38 rules out preeclampsia in SLE
sFlt1:PlGF>85 modestly predicts preeclampsia
Proteinuria impacts prediction accuracy #ACR24 abst#0809 @RheumNow

Bella Mehta bella_mehta
10 months 3 weeks ago
Nationwide US study
-Prevalence of HLH in SLE: 0.13%
-Higher risk in younger, female, and racial minority patients
- Strong association with high mortality #ACR24 abst#0619 @RheumNow

Bella Mehta bella_mehta
10 months 3 weeks ago
Study on #AI-augmented remote care for SLE:
- Combined biometric, self-reported, and NLP-extracted data
- Moderate to strong correlations with physician global assessment
- Potential to improve remote disease management - but now very accurate for now
#ACR24 abst#0635 @RheumNow

Antoni Chan MD (Prof) synovialjoints
10 months 3 weeks ago
Interim analysis of a Phase 4 study of ARD (RA 25%, SLE 25%) patients shows recombinant herpes zoster vaccine(RZV) good safety profile, with no impact on disease activity (flare rates: 13.6% vs. 12.4%). Immunogenicity: 93% response in ARDs vs. 99% in controls. Rituximab & MMF… https://t.co/U3s48fLduX https://t.co/WTvD5shtXB


Bella Mehta bella_mehta
10 months 3 weeks ago
Study on socioeconomic factors in SLE hospitalizations - US wide data
- No insurance & non-metro areas linked to shorter LOS, lower costs, higher mortality
- Higher income & age increase charges
- Targeted interventions needed to improve outcomes
#ACR24 abst#0615 @RheumNow

Bella Mehta bella_mehta
10 months 3 weeks ago
Study on pregnancy outcome disparities in SLE:
- Analyzed 685 women, 1888 pregnancies
- Pre-SLE state linked to fewer live births, higher preeclampsia risk
- Outcomes worse post-SLE diagnosis
#ACR24 abst#0440 @RheumNow https://t.co/NpEYQZ73uo
