Drug Safety

      A#1743
      Are there benefits of getting LDA to remission?
      Remission CDAI <2.8, VLDA 2.8-6, LDA 6-10
      After 1 yr f/u of LD

      Eric Dein ericdeinmd

      10 months 3 weeks ago
      A#1743 Are there benefits of getting LDA to remission? Remission CDAI <2.8, VLDA 2.8-6, LDA 6-10 After 1 yr f/u of LDA, 45% Rem, 40 VLDA, 16 LDA Not in remiss - higher BMI, longer duration, higher resource utilization, worse PRO No clear diff bw remission & VLDA #ACR24 @RheumNow https://t.co/ut7c52JVDr
      Frideres et al. Target trial emulation in RA-ILD. Primar outcome death or respiratory hospitialization. Abatacept (aHR 0

      Richard Conway RichardPAConway

      10 months 3 weeks ago
      Frideres et al. Target trial emulation in RA-ILD. Primar outcome death or respiratory hospitialization. Abatacept (aHR 0.90), tocizilumab (aHR 0.93), tofacitinib (aHR 0.69) vs rituximab. @RheumNow #ACR24 Abstr#1713 https://t.co/fbE8xAnzQ2 https://t.co/uwzH8oAyAT
      A picture is worth a thousand words—and so are the four abstracts behind it! At #ACR24, I highlight the benefits and r

      Akhil Sood MD AkhilSoodMD

      10 months 3 weeks ago
      A picture is worth a thousand words—and so are the four abstracts behind it! At #ACR24, I highlight the benefits and risks of apremilast in #PsA. @RheumNow https://t.co/ospR0qEIsd
      Cyclophosphomide vs Mycophenolate vs Tacrolimus in Lupus Nephritis
      10 months 3 weeks ago
      Chevet et al. What happens when you withdraw tocilizumab after 6 months in PMR? Follow up of SEMAPHORE study. 80.8% rela

      Richard Conway RichardPAConway

      10 months 3 weeks ago
      Chevet et al. What happens when you withdraw tocilizumab after 6 months in PMR? Follow up of SEMAPHORE study. 80.8% relapsed! Median time to relapse 15 weeks. @RheumNow #ACR24 Abstr#1698 https://t.co/9pJ88C05V2
      Is #IL1 inhibition for 4 months a winner in #GCA —NOPE

      Anakinra daily 100mg sc 4/12

      Underpowered but equal relaps

      Janet Pope Janetbirdope

      10 months 3 weeks ago
      Is #IL1 inhibition for 4 months a winner in #GCA —NOPE Anakinra daily 100mg sc 4/12 Underpowered but equal relapses and d/c #steroids not different #relapses esp after d/c #anakinra N=30 d/c due to #COVIDpandemic #1699 #ACR24 @RheumNow @ACRheum https://t.co/1TgloS5x8O
      #HRT is not much of a risk of
      Breast cancer

      Compared to
      A drink a day of #ETOH
      #ACR24 @RheumNow @ACRheum https://t.co/

      Janet Pope Janetbirdope

      10 months 3 weeks ago
      #HRT is not much of a risk of Breast cancer Compared to A drink a day of #ETOH #ACR24 @RheumNow @ACRheum https://t.co/LFgqbFocpb
      de Boysson et al. RCT anakinra in GCA. 30 patients. Week 52 relapse 53% in anakinra vs 46% in placebo. @RheumNow #ACR24

      Richard Conway RichardPAConway

      10 months 3 weeks ago
      de Boysson et al. RCT anakinra in GCA. 30 patients. Week 52 relapse 53% in anakinra vs 46% in placebo. @RheumNow #ACR24 Abstr#1699 https://t.co/sqDWUlkXAX
      Sarilumab is better than #MTX in #PMR

      Reminder #RCT of #MTX in #PMR was a NEGATIVE #trial #1697

      60 % #sarilumab in #RW

      Janet Pope Janetbirdope

      10 months 3 weeks ago
      Sarilumab is better than #MTX in #PMR Reminder #RCT of #MTX in #PMR was a NEGATIVE #trial #1697 60 % #sarilumab in #RWE could d/c #Prednisone after failure of initial #pred #Rx >1yr pred prior vs 40% MTX Comparative effectiveness sari v MTX #1700 #ACR24 @ACRheum @RheumNow https://t.co/4YXIBz0OK7
      A retrospective analysis by Dr. ERayens et al showed that RA pts >/=50y given 2 RZV doses were less likely to develop

      sheila RHEUMarampa

      10 months 3 weeks ago
      A retrospective analysis by Dr. ERayens et al showed that RA pts >/=50y given 2 RZV doses were less likely to develop HZ vs. unvaxxed grp Incidence of PHN was also lower in the vaccinated group (0.2py vs.1.9py) RZV is effective in preventing HZ & PhN @Rheumnow #ACR25 abs0977 https://t.co/JhYBYnLmhl
      Bolhuis et al. PMR MODE study. MTX 25mg/week in recently diagnosed PMR. 52 weeks. 56 patients. Nada, zip, no effect. GC

      Richard Conway RichardPAConway

      10 months 3 weeks ago

      Bolhuis et al. PMR MODE study. MTX 25mg/week in recently diagnosed PMR. 52 weeks. 56 patients. Nada, zip, no effect. GC free remission 67% vs 68%. No difference in any secondary outcome. @RheumNow #ACR24 Abstr#1697 #ACRbest https://t.co/Mb909u1zFT https://t.co/dShyBF4WST

      RA-ILD:
      💡Lifetime prevalence seems low but ~40% can have subclincal.
      💡Screen early in symptomatic pts.
      💡RA dise

      Adela Castro AdelaCastro222

      10 months 3 weeks ago
      RA-ILD: 💡Lifetime prevalence seems low but ~40% can have subclincal. 💡Screen early in symptomatic pts. 💡RA disease control decreases ILD progression and mortality. 💡RA-ILD UIP pattern seems to respond to immunosuppression. #ACR24 @RheumNow https://t.co/q3iACMeYVU
      When you stop 🛑 #TCZ #tocilizumab at
      6 months of #Rx in #PMR
      RELAPSES are V high

      DON’T stop #Toci in PMR too
      Earl

      Janet Pope Janetbirdope

      10 months 3 weeks ago
      When you stop 🛑 #TCZ #tocilizumab at 6 months of #Rx in #PMR RELAPSES are V high DON’T stop #Toci in PMR too Early Rapid and frequent flares #ACR24 @RheumNow @ACRheum #1698 https://t.co/IX5EJOcIY5
      SELECTing the right patients: upadacitinib in GCA
      10 months 3 weeks ago
      This will change my practice!
      #RCT #MMF + #MTX
      superior to
      #Cyclophosphamide then #Azathioprine

      In
      #Tayakasu’s #ar

      Janet Pope Janetbirdope

      10 months 3 weeks ago
      This will change my practice! #RCT #MMF + #MTX superior to #Cyclophosphamide then #Azathioprine In #Tayakasu’s #arteritis N=150 RCT ~1g BID #mycophenolate + 15mg/wk #Methotrexate Vs #cyclo ➡️100mg #azathioprine All got #glucocorticoids #ACR24 @RheumNow @ACRheum #1696 https://t.co/OpRep1vsmx

      Catch up on Conference Podcasts

      ×