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Rheumatoid Arthritis

      Don’t miss the “window of opportunity” for aggressive treatment in early RA!

      with active RA, risk of ILD 6x and

      Jiha Lee JihaRheum

      11 months 2 weeks ago
      Don’t miss the “window of opportunity” for aggressive treatment in early RA! with active RA, risk of ILD 6x and RA-related lung disease 4x higher #ACR24 @RheumNow ABST#0802 https://t.co/yxlfInte6A
      What's the assoc between RA disease activity & ILD?

      Results @MassGenBrigham show early active RA is assoc with
      ➡?

      Mrinalini Dey DrMiniDey

      11 months 2 weeks ago
      What's the assoc between RA disease activity & ILD? Results @MassGenBrigham show early active RA is assoc with ➡️6x incr risk of #ILD ➡️4x incr risk of RA-related lung disease Early DMARDs are vital to reduce articular & extra-articular manifestations! Ab0802 #ACR24 @RheumNow
      Pregnancy is perhaps the oldest treatment in rheumatoid arthritis (RA) and has been associated with a natural improvement in disease control in 50-75% of patients. Others, however, are not as successful with unchanged disease activity or worsening of their autoimmune disease.
      McDermott @jeffsparks et al. SAIL-RA prospective study. 172 early RA patients. RA lund disease in 16%, RA-ILD in 11%. Di

      Richard Conway RichardPAConway

      11 months 2 weeks ago

      McDermott @jeffsparks et al. SAIL-RA prospective study. 172 early RA patients. RA lund disease in 16%, RA-ILD in 11%. Disease activity strongest predictor RA lung disease, HR 4.89, and RA-ILD, HR 6.17. @RheumNow #ACR24 Abstr#0802 #ACRbest https://t.co/ia0koG64mL https://t.co/U1KdgcUfOy

      Ab#0427 #ACR24
      HSS: menopause & systemic rheum disease severity

      1/3 women report worse disease associated w menopa

      Eric Dein ericdeinmd

      11 months 2 weeks ago
      Ab#0427 #ACR24 HSS: menopause & systemic rheum disease severity 1/3 women report worse disease associated w menopause Reported more flares, menopausal symptoms Findings were similar between SLE and RA, but SLE patients were >2x more likely to discuss w their rheum @RheumNow
      ❔Can rheum drugs have beneficial effects on cognition?

      💊Possible benefits with MTX and TNFis but certainly an acti

      Mrinalini Dey DrMiniDey

      11 months 2 weeks ago
      ❔Can rheum drugs have beneficial effects on cognition? 💊Possible benefits with MTX and TNFis but certainly an active area of research and more studies needed #ACR24 @RheumNow https://t.co/lCnIRLwNjK
      A New ACR
      Ab#474 #ACR24
      Hsieh and @NamrataRheum
      Cancer Survival in RA
      Unable to do meta-analysis due to lack of data
      HR for lung

      Eric Dein ericdeinmd

      11 months 2 weeks ago
      Ab#474 #ACR24 Hsieh and @NamrataRheum Cancer Survival in RA Unable to do meta-analysis due to lack of data HR for lung cancer in RA 1.04 No clear evid of increased risk, but more data and studies needed Great research project by a high school student (!!) @RheumNow https://t.co/Sfrf2v2UO4
      Ab#0458 #ACR24
      10 year outcomes of 176 patients with seroneg RA
      32 pts (18%) had change in dx - SpA (11), seropos RA (6)

      Eric Dein ericdeinmd

      11 months 2 weeks ago
      Ab#0458 #ACR24 10 year outcomes of 176 patients with seroneg RA 32 pts (18%) had change in dx - SpA (11), seropos RA (6), OA (5), crystal (3), CTD (3), Ifn-related/paraneopl/RS3PE, sarcoid (1) 40 (23%) had drug-free remission 30 (17%) started b/tsDMARD @RheumNow
      👴🏼 Ageing & RMDs at #ACR24

      🧠 14 factors associated with dementia

      ❗️Justin Levenson tells us that if w

      Mrinalini Dey DrMiniDey

      11 months 2 weeks ago
      👴🏼 Ageing & RMDs at #ACR24 🧠 14 factors associated with dementia ❗️Justin Levenson tells us that if we could address all of these, we could reduce dementia risk by 45%! @RheumNow https://t.co/SgC5KMohXy
      Interim analysis of a Phase 4 study of ARD (RA 25%, SLE 25%) patients shows recombinant herpes zoster vaccine(RZV) good

      Antoni Chan MD (Prof) synovialjoints

      11 months 2 weeks ago
      Interim analysis of a Phase 4 study of ARD (RA 25%, SLE 25%) patients shows recombinant herpes zoster vaccine(RZV) good safety profile, with no impact on disease activity (flare rates: 13.6% vs. 12.4%). Immunogenicity: 93% response in ARDs vs. 99% in controls. Rituximab & MMF… https://t.co/U3s48fLduX https://t.co/WTvD5shtXB
      Can we predict who will develop #RA-#ILD?

      Wheeler et al showed a combination of genetic risk score, peripheral protein

      Mrinalini Dey DrMiniDey

      11 months 2 weeks ago
      Can we predict who will develop #RA-#ILD? Wheeler et al showed a combination of genetic risk score, peripheral protein #biomarkers & clinical risk factors can help identify RA-ILD in RA patients. Does this bring us closer to #PersonalisedMedicine? Ab0799 #ACR24 @RheumNow https://t.co/JZkJNGmLM1
      The use of ultrasound in clinically suspect arthralgia can complement MRI early diagnosis of RA. Abstr#228 Gupta A @Rheu

      Antoni Chan MD (Prof) synovialjoints

      11 months 2 weeks ago
      The use of ultrasound in clinically suspect arthralgia can complement MRI early diagnosis of RA. Abstr#228 Gupta A @RheumNow #ACR24 https://t.co/rpVqZKeMXE
      Galloway et al report OCP/HRT use in RA is not associated with VTE in UK population based study. Increased risk by havin

      Richard Conway RichardPAConway

      11 months 2 weeks ago
      Galloway et al report OCP/HRT use in RA is not associated with VTE in UK population based study. Increased risk by having RA, HR 1.52. Risk OCP HR 1.43, HRT HR 2.32 - neither statistical significant but very wide CI's! Hmm... @RheumNow #ACR24 Abstr#0134 https://t.co/CZNoRfYWe8 https://t.co/uC6jA9lcX9
      Dhir et al. RCT of increasing folic acid from 5-10mg per week to 15-35mg per week if MTX intolerance. No benefit! Althou

      Richard Conway RichardPAConway

      11 months 2 weeks ago
      Dhir et al. RCT of increasing folic acid from 5-10mg per week to 15-35mg per week if MTX intolerance. No benefit! Although significant placebo response and folic acid is relatively benign. @RheumNow #ACR24 Abstr#0525 https://t.co/D3yfV6a8t6 https://t.co/QpDa1alvMz
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