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TNF inhibitor

      TNFis preventing cancer compared to placebo, and JAKi being neutral to placebo and maybe preventing haem cancers also. #
      TNFis preventing cancer compared to placebo, and JAKi being neutral to placebo and maybe preventing haem cancers also. #ACR24 abstract 0989 was certainly provocative. I've shared my thoughts on @RheumNow https://t.co/yQFoUGifEN
      What is the effect of cs/bDMARDs on weight in #PsA?

      ⬇️Weight loss seen with:
      IL17i
      IL23i
      csDMARDs

      ⬆️Weight gai
      1 month ago
      What is the effect of cs/bDMARDs on weight in #PsA? ⬇️Weight loss seen with: IL17i IL23i csDMARDs ⬆️Weight gain seen with: TNFi IL12/23i Important to consider #comorbidity & #BMI in management decisions in PsA Ab2639 #ACR24 @RheumNow
      A#2583
      Apremilast for axial inflamm in PsA, assess by CANDEN MRI scoring
      MOSAIC P4 open label trial
      Reduction in inflamm
      1 month ago
      A#2583 Apremilast for axial inflamm in PsA, assess by CANDEN MRI scoring MOSAIC P4 open label trial Reduction in inflammation seen in vertebral bodies & posteriolateral, not in facet joints No changes in SPARCC SIJ, spine - though low baseline SIJ inflammation @RheumNow #ACR24 https://t.co/3GKEGJbtdc
      A study investigating weight trends in Psoriatic Arthritis (PsA) and the impact of various medications. Analyzing 1754 p
      A study investigating weight trends in Psoriatic Arthritis (PsA) and the impact of various medications. Analyzing 1754 patients, it explored multifactorial influences on weight changes Key findings: - Significant weight loss after starting IL17i, IL23i, and csDMARDs. - TNFi &… https://t.co/qOl2ojV9rL https://t.co/Eh2ZNLeKhn
      #2286🔬Certolizumab Pegol (CZP) in High RF RA

      📊Pooled analysis;N=1180

      💥PBO: High RF=more radiographic progress
      #2286🔬Certolizumab Pegol (CZP) in High RF RA 📊Pooled analysis;N=1180 💥PBO: High RF=more radiographic progression v low RF (Wk24 6.5 v 2.8%,Wk52 17.6 v 10.4%) 💥CZP: min. progression regardless of RF (Wk24 0 v 1.1%;Wk52 5.3 v 3.1%) #ACR24 @RheumNow https://t.co/koel7SDsUb
      @DianeLacaille Canadian biosimilar exp
      Biosimilar transition v originator controls x2 yrs
      Weighted model: no decr in ETN
      1 month ago
      @DianeLacaille Canadian biosimilar exp Biosimilar transition v originator controls x2 yrs Weighted model: no decr in ETN biosimilar discontinuation v originator. IFX shows slight decrease - NOT statistical signif Safety- no difference, slight incr rheum visits @RheumNow #ACR24 https://t.co/0GMfLAyzOo
      Biosimilar switching in practice

      Hyrich: UK experience
      Switching to biosimilar has no immediate benefit to patients but
      1 month ago
      Biosimilar switching in practice Hyrich: UK experience Switching to biosimilar has no immediate benefit to patients but saves NHS money Allows for gain share that can be re-invested in pt care Transparency in switching in explaining to pts and offering resource @RheumNow #ACR24
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