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Vasculitis

      Reason for consult: aortitis- evaluate for systemic causes

      Abstract 1638: Kmetova et al highlight the promising clinic

      Akhil Sood MD AkhilSoodMD

      9 months 2 weeks ago
      Reason for consult: aortitis- evaluate for systemic causes Abstract 1638: Kmetova et al highlight the promising clinical utility of calprotectin as a marker for clinically isolated aortitis @RheumNow #ACR24 https://t.co/2qPaAqWswG
      John Stone
      Steroid-free AAV
      CYCLOPS: steroid tox like “wallpaper on room”
      WGET (ETN for GCA) - taper off by 6 mos -

      Eric Dein ericdeinmd

      9 months 2 weeks ago
      John Stone Steroid-free AAV CYCLOPS: steroid tox like “wallpaper on room” WGET (ETN for GCA) - taper off by 6 mos - neg trial but started tapers RAVE - low doses 8-9 mg/d over 18 mos LoVAS - low dose steroid equally eff ADVOCATE - AVA one month taper, tox score #ACR24 @RheumNow https://t.co/C7eLK5UNPM
      #Blinded by results? 😊
      #Ocular #involvement in #GPA
      👇
      Helped by #rituximab

      👁️ #GPA
      Difficult

      Proptosis
      Ps

      Janet Pope Janetbirdope

      9 months 2 weeks ago
      #Blinded by results? 😊 #Ocular #involvement in #GPA 👇 Helped by #rituximab 👁️ #GPA Difficult Proptosis Pseudotumour Conjunctivitis Scleritis Vasculitis Ocular muscles - diplopia Small case series ‘author defined’ remission in 80% 👍 #RTX #abst0726 @rheumnow #ACR24 https://t.co/GHptelOTyv
      "We look forward to Carol Langfords upcoming leadership at ACR and its newfound focus on ANCA vasculitis as the most imp

      Mike Putman EBRheum

      9 months 2 weeks ago
      "We look forward to Carol Langfords upcoming leadership at ACR and its newfound focus on ANCA vasculitis as the most important disease" 😆😂 -Phil Seo #ACR24 @RheumNow
      The SELECT-GCA study, looking at upadacitinib in GCA, anchored the ACR 2024 opening plenary for a reason - it is highly notable and badly needed.
      Day 1 Recap at ACR24
      Are emulation ‘trials’ helpful, despite the biases that occur with observational data, or do they truly mimic the results of randomized controlled trials (RCTs)?
      New data to guide role of long-term, low dose GC in GPA

      Active GPA s/p tx -> randomized to d/c pred within 1 mo or s

      Brian Jaros, MD Dr_Brian_MD

      9 months 2 weeks ago
      New data to guide role of long-term, low dose GC in GPA Active GPA s/p tx -> randomized to d/c pred within 1 mo or stay on 5mg daily Fewer relapses on 5mg pred but w/qualifications: 👉 most flares = minor 👉 no difference in flares if RTX on board @RheumNow #ACR24 Abst 0774 https://t.co/Jvc40QWLqM
      Should we screen new #PMR pts for #LVV?

      Pts with PMR had lower risk of aortic complications vs #GCA & similar risk

      Mrinalini Dey DrMiniDey

      9 months 2 weeks ago
      Should we screen new #PMR pts for #LVV? Pts with PMR had lower risk of aortic complications vs #GCA & similar risk as gen pop BUT if they developed GCA later, the risk was same as those with new GCA ➡️Screening recommended in new GCA but not PMR pts Ab0859 #ACR24 @RheumNow https://t.co/HsHPGlt5A9
      🤵‍♂️Results from BACHELOR

      ➡️34 PMR pts
      ➡️18 BARI, 16 PBO
      ➡️Primary endpoint: CRP PMR-AS≤10 w/o o

      Mrinalini Dey DrMiniDey

      9 months 2 weeks ago
      🤵‍♂️Results from BACHELOR ➡️34 PMR pts ➡️18 BARI, 16 PBO ➡️Primary endpoint: CRP PMR-AS≤10 w/o oral GC rescue from W0 to 12 78% BARI pts reached primary endpoint vs 13% PBO No new safety signals BARI 4mg 12W, then 2mg 12W➡️36W low disease activity in PMR Ab0858 #ACR24 @RheumNow
      Systematic review suggests (although not provn) that audiovestibular dysfunction may be from APS. Anti-phospholipid &amp

      Dr. John Cush RheumNow

      9 months 2 weeks ago
      Systematic review suggests (although not provn) that audiovestibular dysfunction may be from APS. Anti-phospholipid & HSP-70 Abs found 25-33% w/idiopathic sudden sensorineural hearing loss,. ACL Abs seen in up to 27% w/ sensorineural hearing loss https://t.co/WcmeCP0ryq https://t.co/DiYX57R0uG
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