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      Effect of air pollution in RA

      Prospective cohort 1000+pts w/ 12000+ visits

      Higher levels of pollution
      & specific s

      Aurelie Najm AurelieRheumo

      4 months 1 week ago
      Effect of air pollution in RA Prospective cohort 1000+pts w/ 12000+ visits Higher levels of pollution & specific size of particles PM25 asso w/ -10% higher odd of flare -Higher DAS CRP and CDAI Now the interesting pattern: PM25 exposure increases 3 weeks before flares https://t.co/MOskJzk05g
      Molina et al. 52 weeks of MANHATTAN study. Guselkumab vs second TNFi after failure 1st TNFi in PsA. MDA 52% vs 33%. Remi

      Richard Conway RichardPAConway

      4 months 1 week ago
      Molina et al. 52 weeks of MANHATTAN study. Guselkumab vs second TNFi after failure 1st TNFi in PsA. MDA 52% vs 33%. Remission/LDA 67% vs 62%. @RheumNow #ACR25 Abstr#2373 https://t.co/qdtOlKLfNU
      Higashida-Konishi et al. RA. Insomnia and fatigue in >80%, depression in 13%. RA disease activity is associated with

      Richard Conway RichardPAConway

      4 months 1 week ago
      Higashida-Konishi et al. RA. Insomnia and fatigue in >80%, depression in 13%. RA disease activity is associated with depression, fatigue, and insomnia. @RheumNow #ACR25 Abstr#2254 https://t.co/7SibPW6BBw
      CD19 counts during RTX maintenance therapy do NOT perform well in assessing the risk of relapse

      Interestingly, only yo

      Brian Jaros, MD Dr_Brian_MD

      4 months 1 week ago
      CD19 counts during RTX maintenance therapy do NOT perform well in assessing the risk of relapse Interestingly, only younger age was associated with relapse in this retrospective study @RheumNow #ACR25 Abst 1766 https://t.co/crsFKJ0LnP
      In case you have a (gut) feeling something’s off…
      Abstract 2315: The gut microbiome in #SpA 🔬
      ⬆️ Proteobacter

      Akhil Sood MD, MS AkhilSoodMD

      4 months 1 week ago
      In case you have a (gut) feeling something’s off… Abstract 2315: The gut microbiome in #SpA 🔬 ⬆️ Proteobacteria (incl. Escherichia spp) ⬇️ Firmicutes (“good” bacteria) Higher disease activity ↔️ lower alpha diversity @RheumNow #ACR25
      Can AI predict who stops their RA meds?

      In older adults on b/tsDMARDs, interpretable ML found frailty, comorbidity &amp

      Jiha Lee JihaRheum

      4 months 1 week ago
      Can AI predict who stops their RA meds? In older adults on b/tsDMARDs, interpretable ML found frailty, comorbidity & age top the list for nonadherence risk. @RheumNow #ACR25 Abstract#2287
      Zavada et al. 52 patients. bDMARD therapy improves sexual function at 6 months in r-axSpA. Improvements in function, des

      Richard Conway RichardPAConway

      4 months 1 week ago
      Zavada et al. 52 patients. bDMARD therapy improves sexual function at 6 months in r-axSpA. Improvements in function, desire, satisfaction in those with baseline erectile dysfunction @RheumNow #ACR25 Abstr#2346 https://t.co/IUMGCFnXZh
      Konsta et al. Adding NSAID to TNF inhibits spinal but not hip radiograpic progress. 262 patients, TNF+NSAID 100, TNF alo

      Richard Conway RichardPAConway

      4 months 1 week ago
      Konsta et al. Adding NSAID to TNF inhibits spinal but not hip radiograpic progress. 262 patients, TNF+NSAID 100, TNF alone 162. New syndesmophytes 36% vs 58%. ΔmSASSS-score/year 0.1 vs 0.7. No effect on progression of hip radiographs. @RheumNow #ACR25 Abstr#2359 #ACRBest https://t.co/k9j2M2E3ze
      Paging the pharmacist
      Abstract 1973: Dedicated clinic pharmacist -> benefits
      Tasks included:
      🔹 74% PA support
      🔹

      Akhil Sood MD, MS AkhilSoodMD

      4 months 1 week ago
      Paging the pharmacist Abstract 1973: Dedicated clinic pharmacist -> benefits Tasks included: 🔹 74% PA support 🔹 55% patient education 🔹 40% medication management ~50% pts had clinically meaningful improvement Providers report ↑ care quality & ↓ admin burden @RheumNow #ACR25
      Hojiej et al. Prevalence and Impact of lifestyle factors in PsA. Lifestyle factors impacted disease activity. Cumulative

      Richard Conway RichardPAConway

      4 months 1 week ago
      Hojiej et al. Prevalence and Impact of lifestyle factors in PsA. Lifestyle factors impacted disease activity. Cumulative effect of increasing number of factors @RheumNow #ACR25 Abstr#2309 https://t.co/oDGQyLBRDO
      MAINRITSEG: RTX vs. AZA for maintenance in EGPA

      RTX not superior in primary remission outcome
      RTX favored in secondary

      Brian Jaros, MD Dr_Brian_MD

      4 months 1 week ago
      MAINRITSEG: RTX vs. AZA for maintenance in EGPA RTX not superior in primary remission outcome RTX favored in secondary outcome of remission with pred <4mg daily Limitation: only ~50% pt with FFS 1+ @RheumNow #ACR25 Abst 1765 https://t.co/dh5ZWCT12T
      Girolami et al. VA study. Safety of DMARDs in RA following melanoma. 644 patients. 3 year all cause mortality. No signif

      Richard Conway RichardPAConway

      4 months 1 week ago
      Girolami et al. VA study. Safety of DMARDs in RA following melanoma. 644 patients. 3 year all cause mortality. No significant difference, but graph sure looks like b/tsDMARDs are better. No melanoma specific mortality/recurrence data however. @RheumNow #ACR25 Abstr#2237 #ACRBest https://t.co/IN4LDkioT7
      Is RA-ILD associated with/ higher risk of infection?

      Retrospective US cohort study
      151 RA-ILD
      980 matched controls

      79%

      Aurelie Najm AurelieRheumo

      4 months 1 week ago
      Is RA-ILD associated with/ higher risk of infection? Retrospective US cohort study 151 RA-ILD 980 matched controls 79% higher risk of any and pulmonary infections in RA-ILD Pathogen type: bacterial, viral and fungi Some of these infections are preventable! Take Home: https://t.co/fPmRjLL7Po
      In DISCOVER-2, male PsA patients had greater radiographic progression than females despite similar baseline scores. Earl

      Antoni Chan MD (Prof) synovialjoints

      4 months 1 week ago
      In DISCOVER-2, male PsA patients had greater radiographic progression than females despite similar baseline scores. Early joint response (W8 cDAPSA LDA) was linked to less progression more strongly in men. Highlights the sex differences in PsA outcomes. Abstract#2345 @RheumNow https://t.co/zIo59FYPVg
      Macedo et al. Increasing exercise improved QoL in axSpA. Mobility limitation and obesity worsened it. At least to some d

      Richard Conway RichardPAConway

      4 months 1 week ago
      Macedo et al. Increasing exercise improved QoL in axSpA. Mobility limitation and obesity worsened it. At least to some degree these effects appear independent. @RheumNow #ACR25 Abstr#2326 https://t.co/Ei4cKTNHyn
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