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      CAR-T toxicity in hematology
      (the things we have to look out for in rheumatology, as application of CAR-T potentially br

      David Liew drdavidliew

      5 days 7 hours ago
      CAR-T toxicity in hematology (the things we have to look out for in rheumatology, as application of CAR-T potentially broadens) @andrew02114 @MGHCancerCenter with the heme-onc point of view in the #ACR25 BCRC @RheumNow https://t.co/1YjadL7LCF
      Andrew Yee @andrew02114 of @MGHCancerCenter details out how quickly the CAR-T paradigm changed in myeloma/lymphoma - fro

      David Liew drdavidliew

      5 days 7 hours ago

      Andrew Yee @andrew02114 of @MGHCancerCenter details out how quickly the CAR-T paradigm changed in myeloma/lymphoma - from newsworthy to routine. Now that much more about CAR-T has been worked out, will adoption be quicker in autoimmune disease? #ACR25 BCRC pre-meeting @RheumNow https://t.co/oNuPXCwWQ9

      #SLE #DORIS #remission is RARE and without #prednisone even rarer

      #ASIA #Pacific 5K pts over 10 yrs

      A call to do bett

      Janet Pope Janetbirdope

      5 days 7 hours ago
      #SLE #DORIS #remission is RARE and without #prednisone even rarer #ASIA #Pacific 5K pts over 10 yrs A call to do better 82% LLDAS, 70% remission, 31% GC-free remission (REM-0) at least once abst#595 @ACRheum @RheumNow #ACRBest https://t.co/OK6sYnqs81
      Rheum Now Rheumatology Round-Up — LIVE
      Join Drs. Jack Cush & Arthur Kavanaugh for this livestream with two of rheu

      Dr. John Cush RheumNow

      5 days 7 hours ago
      Rheum Now Rheumatology Round-Up — LIVE Join Drs. Jack Cush & Arthur Kavanaugh for this livestream with two of rheumatology’s most trusted voices: this Friday, Oct 31 at 12 PM CST for break down of the latest breakthroughs and hottest topics in rheumatology from #ACR25. 📡 Live https://t.co/G6jKiHYVoR
      #Urinary #biomarkers #lupus #nephritis
      #Tenascin C -suggests repair, fibrosis, progress of #LN
      #IL16, #CD163, & mor

      Janet Pope Janetbirdope

      5 days 7 hours ago
      #Urinary #biomarkers #lupus #nephritis #Tenascin C -suggests repair, fibrosis, progress of #LN #IL16, #CD163, & more for LN activity Sometime a biomarker may replace repeat #kidney #biopsies? #AMP group #Accelerated #Medicines #Program #ACR24 @ACRheum @RheumNow abst#851
      What to use in future for active #Sjogren's #SjD
      B cell depletion, signal attenuation
      Ianalumab 2+ phase3 RCTs
      Telitacep

      Janet Pope Janetbirdope

      5 days 7 hours ago
      What to use in future for active #Sjogren's #SjD B cell depletion, signal attenuation Ianalumab 2+ phase3 RCTs Telitacept +RCT Nipocalimab FcRn +Ph2 Dazodalibep CD40L +Ph2 +RCTs HCQ+Lef Rituximab ?BTKi #ACR25 @ACRheum @RheumNow abst#LB24, LB11
      #MTX is NOT the same as TCZ in #GCA in RCT
      #TCZ did better

      So use an advanced Rx for GCA
      ex TCZ, Upa when approved
      MET

      Janet Pope Janetbirdope

      5 days 7 hours ago
      #MTX is NOT the same as TCZ in #GCA in RCT #TCZ did better So use an advanced Rx for GCA ex TCZ, Upa when approved METOGiA RCT - more relapses in MTX abst#891 #ACR25 @ACRheum @RheumNow https://t.co/wsEKGF8dW2
      Will #PAD4 levels predict pts w #CCP positive #arthralgia who will develop #RA?
      Leeds study - 79 at risk pts
      PAD4 levels

      Janet Pope Janetbirdope

      5 days 7 hours ago
      Will #PAD4 levels predict pts w #CCP positive #arthralgia who will develop #RA? Leeds study - 79 at risk pts PAD4 levels may predicting #rheumatoid #arthritis development #ACR25 @RheumNow @ACRheum abst#832 https://t.co/dnAA6z3NJQ
      #GCA & #PMR @ACRheum #ACR25
      #gamechangers #ACRBest
      Yr 2 Select-GCA abst#776
      #upadacitinib in yr2 of GCA REDUCES flar

      Janet Pope Janetbirdope

      5 days 7 hours ago
      #GCA & #PMR @ACRheum #ACR25 #gamechangers #ACRBest Yr 2 Select-GCA abst#776 #upadacitinib in yr2 of GCA REDUCES flares HELPFUL info ?ability to get drug for 2 yrs hopefully Failed Phase3 RCT of #secukinumab in #GCA helped #PMR abst#1175 & +Ph3 for PMR REPLENISH RCT @RheumNow https://t.co/5lH6HXhnfg
      What happens if you have #axSpA & concomitant #FM?

      Pts with both have less TNFi retention,
      -residual pain may lead

      Janet Pope Janetbirdope

      5 days 7 hours ago
      What happens if you have #axSpA & concomitant #FM? Pts with both have less TNFi retention, -residual pain may lead to d/c Rx. Need to determine if axSpA pt has #fibromyalgia as there may not be objective findings if no peripheral arthritis in axSpA. #ACR25 @RheumNow abst#534
      Post-CAR-T myelopathy has been an issue in heme onc, and is still an unpredictable quantity without a clear cause. Will

      David Liew drdavidliew

      5 days 8 hours ago

      Post-CAR-T myelopathy has been an issue in heme onc, and is still an unpredictable quantity without a clear cause. Will this be a problem for autoimmune CAR-T as we gain more experience? @CarolineDiorio @ChildrensPhila in the #ACR25 BCRC pre-meeting @RheumNow https://t.co/RhhdOiyEAX

      When should you order a renal bx in suspected #LN?

      Active urinary sediment
      Used to be #UPCR 500g/g or more
      Abst#772 loo

      Janet Pope Janetbirdope

      5 days 8 hours ago
      When should you order a renal bx in suspected #LN? Active urinary sediment Used to be #UPCR 500g/g or more Abst#772 looked at UPCR 250g/g to 499 71% + LN and half needed Rx esp if Low C3,C4 Black race Petri, Baltimore #lupus #cohort #ACR25 @ACRheum @RheumNow
      Next Generation T-Cell Engager: The Future

      Dr. Alfred Kim reviews abstract 0001 presented at #ACR25.

      https://t.co/vmZ

      Dr. John Cush RheumNow

      5 days 21 hours ago
      Next Generation T-Cell Engager: The Future Dr. Alfred Kim reviews abstract 0001 presented at #ACR25. https://t.co/vmZYfmKCm8 https://t.co/PkLOs9lZ8l
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