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David Liew drdavidliew
1 year 4 months ago
Wasn’t following the SLE stuff #EULAR2023 but heard a lot of talk about both telitacicept & CAR-T, including meeting highlights by Christian Dejaco.
Both look pretty exciting - the longer the sustained remission with CAR-T, the more it looks like maybe the real deal @RheumNow https://t.co/oKzb8ojTcz
Md Yuzaiful Md Yusof Yuz6Yusof
1 year 4 months ago
#EULAR2023 Clinical Highlights. Osteoarthritis. OP0071 Single centre Phase 2 RCT showed Denosumab halted erosion in Erosive OA at 24 weeks treatment, and the treatment effect enhances after 48 weeks vs PBO @RheumNow https://t.co/YWFUg3cp7P
Dr. John Cush RheumNow
1 year 4 months ago
Tune it at 1pm EST for RheumNow's daily #EULAR23 recaps. You can find us live on YouTube, Twitter and LinkedIn. https://t.co/i8rm5t8mFS
Dr. John Cush RheumNow
1 year 4 months ago
RheumNow’s expanded coverage of the #EULAR2023 annual meeting is sponsored in part by Bristol Myers Squibb. All content is chosen by RheumNow and its faculty.
Bella Mehta bella_mehta
1 year 4 months ago
Depositions of crystals in coronary arteries were associated with MACE @rheumnow #EULAR2023 https://t.co/VHxtsB7ZsA
Aurelie Najm AurelieRheumo
1 year 4 months ago
Adherence to TNFi follows different trajectories
Cluster 1: “moderate then high” 51%
Cluster 2: “moderate then low” 20%
Cluster 3: “low adherence, to discontinuation” 18%
Cluster 4: “low then high adherence” 11%
Most demographic & clinical features CAN NOT predict trajectory! https://t.co/4wLg6b70Kl
David Liew drdavidliew
1 year 4 months ago
@eular_org recommendations session #EULAR2023 - and the first recommendation is one I’m so glad is up front:
Adult Onset Still’s Disease (AOSD) and Systemic JIA (sJIA) are the same disease.
If anything, it’s the really young sJIA (<18 months old) which is different @RheumNow https://t.co/OCDeeNtNoR
David Liew drdavidliew
1 year 4 months ago
@eular_org recommendation for AOSD/sJIA:
An IL-1 or IL-6 inhibitor should be initiated as early as possible when the diagnosis is established
#EULAR2023 @RheumNow https://t.co/xNUdpGDxb9
Md Yuzaiful Md Yusof Yuz6Yusof
1 year 4 months ago
#EULAR2023 #POS1156 Previous case series reported ~9% de novo nephritis in #SLE pts treated with belimumab for non-renal lupus. Post-hoc analysis of 5 BEL Non-LN RCTs showed 8% had de novo LN. Risk increased in Asians but lowered with low dose BEL or s/c form @RheumNow https://t.co/GqAr3tppWh
David Liew drdavidliew
1 year 4 months ago
One new overarching principle for @eular_org PsA recommendations:
“The choice of treatment should take account of safety considerations regarding individual MoA to optimize the benefit-risk profile”
Wonder what triggered that
#EULAR2023 #oralsurveillance @RheumNow https://t.co/19BfJQz4Za
Dr. Antoni Chan synovialjoints
1 year 4 months ago
The incidence of MACEs at 8 years is low in AS patients treated with NSAIDs. Study of 22929 patients, NSAIDs (SHR: 0.40 [0.32-0.49], p<0.001) and anti-TNFs (SHR: 0.61 [0.47-0.81], p<0.001) associated with a lower risk of MACE, Fakih O, Abst#POS0301, #EULAR2023 @RheumNow https://t.co/i5GZMcJwyO
David Liew drdavidliew
1 year 4 months ago
New 2023 @eular_org SLE recommendations
Key changes, in response to evidence:
- more caution re: steroids
- biologics earlier
- combo therapy (BEL or CNI/VCS) considered for lupus nephritis
#EULAR2023 @RheumNow https://t.co/J3Lp8owRyT
David Liew drdavidliew
1 year 4 months ago
Key points from #EULAR2023 on how to manage SLE
@RheumNow https://t.co/vJy7Cg7w8N
Dr. Antoni Chan synovialjoints
1 year 4 months ago
Late Breaker - EULAR 2023 update on imaging of large vessel vasculitis. Ultrasound is now recommended as first line imaging test in all patients with suspected GCA, and axillary arteries should be in the standard examination, Dejaco C et al, Abst#LB0009, #EULAR2023 @RheumNow https://t.co/ya41nJG6qK
Janet Pope Janetbirdope
1 year 4 months ago
#ClinicalPearl This is cool - think of SGLT2 for #lupus #nephritis? presented at #SLE recommendations @RheumNow #EULAR2023 @eular_org https://t.co/8mbNt2n64v
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