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Anti-Rheumatic Rx

      Management of SLE:
      -Treat early to prevent organ damage
      -Taper GC to <5mg/d in the first 6m when feasible
      -New therap

      Adela Castro AdelaCastro222

      4 months 1 week ago
      Management of SLE: -Treat early to prevent organ damage -Taper GC to <5mg/d in the first 6m when feasible -New therapies are promising but still unmet needs in LN, limited global access and lacking data in pregnancy. #EULAR2025 @RheumNow https://t.co/UKK8sTYJD2
      #EULAR2025 Abstr#OP0035 SGLT2-i and GLP-1 agonist are increasingly used to treat diabetes. Population based study in Can

      Md Yuzaiful Md Yusof Yuz6Yusof

      4 months 1 week ago
      #EULAR2025 Abstr#OP0035 SGLT2-i and GLP-1 agonist are increasingly used to treat diabetes. Population based study in Canada showed no significant difference in risk of developing an autoimmune rheumatic disease with GLP-1-RA or SGLT2i relative to DPP4i treatment @RheumNow https://t.co/CvPcOqehtl
      +RCT in #pSjD #Sjogrens #Disease

      #Leflunomide + #hydroxychloroquine
      Vs #PBO

      2nd study to show this - same group

      need

      Janet Pope Janetbirdope

      4 months 1 week ago
      +RCT in #pSjD #Sjogrens #Disease #Leflunomide + #hydroxychloroquine Vs #PBO 2nd study to show this - same group need to know ▶️what pt to use this in ▶️is there diff organ improvements ⬆️#ESSDAI ⬇️RF ⬇️Ig’s Easy to prescribe ?early, mild dx #EULAR2025 @RheumNow @eular_org https://t.co/JE0VyFRXc6
      #EULAR2025 Based on the updated EULAR Guidelines on #lupus nephritis, should all patients receive early Combination ther

      Md Yuzaiful Md Yusof Yuz6Yusof

      4 months 1 week ago
      #EULAR2025 Based on the updated EULAR Guidelines on #lupus nephritis, should all patients receive early Combination therapies for remission induction? @RheumNow
      In BIODOPT study (RA, PsA, axSpA), disease activity-guided tapering of biologics (incl. biosimilars) maintained QALY (Δ

      Antoni Chan MD (Prof) synovialjoints

      4 months 1 week ago
      In BIODOPT study (RA, PsA, axSpA), disease activity-guided tapering of biologics (incl. biosimilars) maintained QALY (Δ0.008, NS) while lowering biologic costs (Δ€–1,979 [95%CI –3,798;–161]) & total hospital costs (Δ€–1,936 [95%CI –3,753;–119]) over 18mo. Supports https://t.co/CJUpfU2oRA
      ARIAA study: longer-term data now

      High-risk ACPA+ clinically suspect arthralgias
      abatacept for 6mo, then stop altogethe

      David Liew drdavidliew

      4 months 1 week ago
      ARIAA study: longer-term data now High-risk ACPA+ clinically suspect arthralgias abatacept for 6mo, then stop altogether Really impressive long-term effect also noting success of APIPPRA, abatacept flicks off some very early RA, at least for a while #EULAR2025 OP0325 @RheumNow https://t.co/AeRrUKPPiK https://t.co/jtynyD0ioO
      EULAR FMF recommendations 2025:
      still emphasis on colchicine adherence to maximal dose
      +/- bDMARDs if needed for control

      David Liew drdavidliew

      4 months 1 week ago
      EULAR FMF recommendations 2025: still emphasis on colchicine adherence to maximal dose +/- bDMARDs if needed for control +/- csDMARDs for residual chronic MSK involvement new: consider tapering bDMARD if remission >6mo See the treatment algorithm below⬇️ #EULAR2025 @RheumNow https://t.co/Hy6DOKzfUL
      FMF #Recommendations

      🔺️Start Colchicine in All (& continue for confirmed pts)
      🔺️Single or divided dose, d

      Nelly ZIADE 🍀 Nellziade

      4 months 1 week ago
      FMF #Recommendations 🔺️Start Colchicine in All (& continue for confirmed pts) 🔺️Single or divided dose, depend on adherence & tolerance 🔺️Max dose 2 mg children, 3 mg adults 🔺️if failure: add IL1i (6 RCT) (2 for IL6i) 🔺️Add c or bDMARd if MSK #EULAR2025 @RheumNow https://t.co/fPyQrLbb6S
      FMF #Recommendations

      During attack:
      🔺️No use of increasing Colchicine
      🔺️No use for corticosteroids and opioi

      Nelly ZIADE 🍀 Nellziade

      4 months 1 week ago
      FMF #Recommendations During attack: 🔺️No use of increasing Colchicine 🔺️No use for corticosteroids and opioid 🔺️Use NSAIDs #EULAR2025 @RheumNow https://t.co/jJjWJra7yr
      FMF #Recommendations

      #Colchicine can be fatal

      🔺️Beware of drug interactions
      🔺️Mostly statins in adults
      🔺?

      Nelly ZIADE 🍀 Nellziade

      4 months 1 week ago
      FMF #Recommendations #Colchicine can be fatal 🔺️Beware of drug interactions 🔺️Mostly statins in adults 🔺️Macrolides in children #EULAR2025 @RheumNow https://t.co/SYGLpAJXFu
      “That is why this task force continues to say: nothing is better than methotrexate and glucocorticoids to start”

      -

      David Liew drdavidliew

      4 months 1 week ago
      “That is why this task force continues to say: nothing is better than methotrexate and glucocorticoids to start” - Josef Smolen, on RA treatment #EULAR2025 @RheumNow https://t.co/AbkgWS8tvH
      URAT1 inhibitors look like the way to go in Gout!

      Presented in multiple abstracts at #EULAR2025

      Pozdeutinurad Ph2 lon

      Aurelie Najm AurelieRheumo

      4 months 1 week ago
      URAT1 inhibitors look like the way to go in Gout! Presented in multiple abstracts at #EULAR2025 Pozdeutinurad Ph2 long term safety data chronic gouty arthritis + tophi OP0300 Ph3 RCT of Ruzinurad in hyperuricemia/primary gout OP0302 Ph 2b RCT of SAP-001 Refractory Gout +/-
      #EULAR2025 @eular_org update

      #Recommendations #Rheumatoid #Rx

      prof Smolen
      subtle diff between former guidelines

      MTX

      Janet Pope Janetbirdope

      4 months 1 week ago
      #EULAR2025 @eular_org update #Recommendations #Rheumatoid #Rx prof Smolen subtle diff between former guidelines MTX+GC 👇 D/C GCs rapidly 👇 If inadequate response 👇 Other csDMARDs are OUT ❎ ✅go to bDMARD or tsDMARD* TsDMARD after safety assessed @RheumNow RecommendatnII https://t.co/yUrLdk6Eg1
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