Anti-Rheumatic Rx
Adela Castro AdelaCastro222
4 months 1 week ago
Management of SLE:
-Treat early to prevent organ damage
-Taper GC to <5mg/d in the first 6m when feasible
-New therapies are promising but still unmet needs in LN, limited global access and lacking data in pregnancy.
#EULAR2025 @RheumNow https://t.co/UKK8sTYJD2
Md Yuzaiful Md Yusof Yuz6Yusof
4 months 1 week ago
#EULAR2025 Abstr#OP0035 SGLT2-i and GLP-1 agonist are increasingly used to treat diabetes. Population based study in Canada showed no significant difference in risk of developing an autoimmune rheumatic disease with GLP-1-RA or SGLT2i relative to DPP4i treatment @RheumNow https://t.co/CvPcOqehtl
Janet Pope Janetbirdope
4 months 1 week ago
+RCT in #pSjD #Sjogrens #Disease
#Leflunomide + #hydroxychloroquine
Vs #PBO
2nd study to show this - same group
need to know
▶️what pt to use this in
▶️is there diff organ improvements
⬆️#ESSDAI
⬇️RF ⬇️Ig’s
Easy to prescribe
?early, mild dx
#EULAR2025 @RheumNow @eular_org https://t.co/JE0VyFRXc6
Md Yuzaiful Md Yusof Yuz6Yusof
4 months 1 week ago
#EULAR2025 Based on the updated EULAR Guidelines on #lupus nephritis, should all patients receive early Combination therapies for remission induction? @RheumNow
Antoni Chan MD (Prof) synovialjoints
4 months 1 week ago
In BIODOPT study (RA, PsA, axSpA), disease activity-guided tapering of biologics (incl. biosimilars) maintained QALY (Δ0.008, NS) while lowering biologic costs (Δ€–1,979 [95%CI –3,798;–161]) & total hospital costs (Δ€–1,936 [95%CI –3,753;–119]) over 18mo. Supports https://t.co/CJUpfU2oRA
David Liew drdavidliew
4 months 1 week ago
ARIAA study: longer-term data now
High-risk ACPA+ clinically suspect arthralgias
abatacept for 6mo, then stop altogether
Really impressive long-term effect
also noting success of APIPPRA, abatacept flicks off some very early RA, at least for a while
#EULAR2025 OP0325 @RheumNow https://t.co/AeRrUKPPiK https://t.co/jtynyD0ioO
David Liew drdavidliew
4 months 1 week ago
EULAR FMF recommendations 2025:
still emphasis on colchicine adherence to maximal dose
+/- bDMARDs if needed for control
+/- csDMARDs for residual chronic MSK involvement
new: consider tapering bDMARD if remission >6mo
See the treatment algorithm below⬇️
#EULAR2025 @RheumNow https://t.co/Hy6DOKzfUL
Nelly ZIADE 🍀 Nellziade
4 months 1 week ago
FMF #Recommendations
🔺️Start Colchicine in All (& continue for confirmed pts)
🔺️Single or divided dose, depend on adherence & tolerance
🔺️Max dose 2 mg children, 3 mg adults
🔺️if failure: add IL1i (6 RCT) (2 for IL6i)
🔺️Add c or bDMARd if MSK
#EULAR2025
@RheumNow https://t.co/fPyQrLbb6S
Nelly ZIADE 🍀 Nellziade
4 months 1 week ago
FMF #Recommendations
During attack:
🔺️No use of increasing Colchicine
🔺️No use for corticosteroids and opioid
🔺️Use NSAIDs
#EULAR2025
@RheumNow https://t.co/jJjWJra7yr
Nelly ZIADE 🍀 Nellziade
4 months 1 week ago
FMF #Recommendations
#Colchicine can be fatal
🔺️Monitor regularly
#EULAR2025
@RheumNow https://t.co/VJZYPaBrvE
Nelly ZIADE 🍀 Nellziade
4 months 1 week ago
FMF #Recommendations
#Colchicine can be fatal
🔺️Beware of drug interactions
🔺️Mostly statins in adults
🔺️Macrolides in children
#EULAR2025
@RheumNow https://t.co/SYGLpAJXFu
David Liew drdavidliew
4 months 1 week ago
“That is why this task force continues to say: nothing is better than methotrexate and glucocorticoids to start”
- Josef Smolen, on RA treatment
#EULAR2025 @RheumNow https://t.co/AbkgWS8tvH
David Liew drdavidliew
4 months 1 week ago
The key changes for the new 2025 EULAR recommendations on RA treatment
#EULAR2025 @RheumNow https://t.co/dp5LnoFdpW
Aurelie Najm AurelieRheumo
4 months 1 week ago
URAT1 inhibitors look like the way to go in Gout!
Presented in multiple abstracts at #EULAR2025
Pozdeutinurad Ph2 long term safety data chronic gouty arthritis + tophi OP0300
Ph3 RCT of Ruzinurad in hyperuricemia/primary gout OP0302
Ph 2b RCT of SAP-001 Refractory Gout +/-
Janet Pope Janetbirdope
4 months 1 week ago
#EULAR2025 @eular_org update
#Recommendations #Rheumatoid #Rx
prof Smolen
subtle diff between former guidelines
MTX+GC
👇
D/C GCs rapidly
👇
If inadequate response
👇
Other csDMARDs are OUT ❎
✅go to bDMARD or tsDMARD*
TsDMARD after safety assessed
@RheumNow RecommendatnII https://t.co/yUrLdk6Eg1

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