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Vasculitis

      Women with antiphospholipid syndrome and lupus anti-coagulant are at high risk of developing adverse pregnancy outcomes (APO). Usual care includes low molecular weight heparin (LMWH) and low dose aspirin (LDA). Despite these therapies, APO have been reported up to 40%. An important question is whether add-on immunosuppressive therapy could improve APO.
      Management of AAV:
      1.High dose GC f/b reduced dose taper ‼️caution in pts w/severe renal dz and RTX induction.
      2. RT

      Adela Castro AdelaCastro222

      3 weeks 1 day ago
      Management of AAV: 1.High dose GC f/b reduced dose taper ‼️caution in pts w/severe renal dz and RTX induction. 2. RTX effective for induction and maintenance, best for relapses. 3.PLEX: in RPGN pts if accesible ⚠️ risk for infection. 4.Avacopan: for faster GC weaning. No https://t.co/kfZ4gM38KG
      Pearls on EGPA:
      1. GC are mainstay for mild
      dz
      2. Organ threatening/relapsing➡️CYP (RTX alternative)
      3. W/o organ th

      Adela Castro AdelaCastro222

      3 weeks 1 day ago
      Pearls on EGPA: 1. GC are mainstay for mild dz 2. Organ threatening/relapsing➡️CYP (RTX alternative) 3. W/o organ threatening➡️ anti-IL-5/IL-5R. 4. IL5i are less effective for ENT 5. Consider sx for nasal polyps. #EULAR2025 @RheumNow https://t.co/zoJEWxafsN
      #ClinicalPearls
      For
      #cartilage #swelling in #relapsing #polychrondritis

      Ask for #pics

      #Levamisole in #cocaine
      #infect

      Janet Pope Janetbirdope

      3 weeks 1 day ago
      #ClinicalPearls For #cartilage #swelling in #relapsing #polychrondritis Ask for #pics #Levamisole in #cocaine #infection - uncommon - from piercing Acute #bacterial v chronic #lymphoma #malignancy #vasculitis #Trauma Hx, duration, fever can be helpful #EULAR2025 @RheumNow https://t.co/X2b6VHYsYa
      #Relapsing_Polychondritis

      Main differential diagnosis is GPA

      🔺️No ANCA and no renal involvement in relapsing poly

      Nelly ZIADE 🍀 Nellziade

      3 weeks 1 day ago
      #Relapsing_Polychondritis Main differential diagnosis is GPA 🔺️No ANCA and no renal involvement in relapsing polychondritis @Lupusreference #EULAR2025 @RheumNow https://t.co/QUJZ3EDjj3
      Tips for Dx RP:
      1. Suspect the dx and recognize chondritis.
      2. Rule out mimickers
      3.Tracheal involvement shows swelling

      Adela Castro AdelaCastro222

      3 weeks 1 day ago
      Tips for Dx RP: 1. Suspect the dx and recognize chondritis. 2. Rule out mimickers 3.Tracheal involvement shows swelling>stenosis (helps ≠from GCA) 4. CV, heme, derm manifestations 🧐VEXAS. 5. biopsy not useful unless ≠ from GCA. Fantastic session by @Lupusreference https://t.co/W4DgfeRULF
      Great talk by @Lupusreference on Relapsing Polychondritis and a highlight of #EULAR2025. Do not forget about the articul

      Antoni Chan MD (Prof) synovialjoints

      3 weeks 1 day ago
      Great talk by @Lupusreference on Relapsing Polychondritis and a highlight of #EULAR2025. Do not forget about the articular presentations of relapsing polychondritis @RheumNow https://t.co/1xZY7VkX1z
      What kills in GCA?

      Greek national prospective cohort, small numbers and no doubt some channeling bias, but:

      Steroids (

      David Liew drdavidliew

      3 weeks 2 days ago
      What kills in GCA? Greek national prospective cohort, small numbers and no doubt some channeling bias, but: Steroids (absence of DMARD use) is more of a factor than CV disease in GCA mortality. With new options, all GCA pts should be on something #EULAR2025 POS0960 @RheumNow https://t.co/Wmvf6tEvaF
      New work presented at the 2025 annual EULAR congress in Barcelona focuses on the recombinant zoster vaccine (RZV), which contains recombinant glycoprotein E – the major target of CD4+T-cells. The abstract describes the tolerability and safety of RZV in patients with inflammatory rheumatic and musculoskeletal diseases (iRMD), showcasing interim data from an ongoing study.
      #ANCA #vasculitis is not created equally

      REVEAL cohort 588 ANCA

      Initial & 12 months #BVAS (activity index)
      mean ?

      Janet Pope Janetbirdope

      3 weeks 2 days ago
      #ANCA #vasculitis is not created equally REVEAL cohort 588 ANCA Initial & 12 months #BVAS (activity index) mean ⬇️BVAS over 1 yr in all groups #GPA #MPA #eGPA 5yr survival not = over time ⬆️survival in eGPA & GPA vs MPA #POS0329 #EULAR2025 @RheumNow @eular_org https://t.co/cUKytqNZnS
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