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      ❀️ Do biologics differ in MACE risk in PsA?

      YES - JAKi highest risk after 2.5yrs vs TNFi/IL-17i/IL-23i in a retros

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      ❀️ Do biologics differ in MACE risk in PsA? YES - JAKi highest risk after 2.5yrs vs TNFi/IL-17i/IL-23i in a retrospective cohort of 22,246pts. OP0181 #EULAR2026 @RheumNow https://t.co/eQdBtMfRAY
      After TNFi secondary failure: does MOA switch beat TNFi cycling? UK RWD (n=155): yes for #PsA (76% vs 57% drug survival

      Jiha Lee JihaRheum

      2 months ago
      After TNFi secondary failure: does MOA switch beat TNFi cycling? UK RWD (n=155): yes for #PsA (76% vs 57% drug survival at 12m) and axSpA (80% vs 68%), but not RA. Yet 74% of axSpA pts still got another TNFi. Evidence vs practice gap in plain sight. @RheumNow #EULAR2026 POS0776
      Real-world bimekizumab in SpA/#PsA (BIMPACT, n=223): 76% retention at 12mo, even with 54% having prior IL-17i exposure.

      Jiha Lee JihaRheum

      2 months ago
      Real-world bimekizumab in SpA/#PsA (BIMPACT, n=223): 76% retention at 12mo, even with 54% having prior IL-17i exposure. Effective after IL-17Ai failure. Oral candidiasis higher in PsA (16.5%) vs SpA (3.3%); led to discontinuation in ~25%. @RheumNow #EULAR2026 POS0798/POS0810
      Impt pts to consider in D2T CLE by Prof Wittmann:
      If tx is not working, ask yourself: is the dx correct? adherence?
      Mai

      sheila RHEUMarampa

      2 months ago
      Impt pts to consider in D2T CLE by Prof Wittmann: If tx is not working, ask yourself: is the dx correct? adherence? Main message: treat early When damage is present, tx doesn’t really provide considerable improvements Future drxns? Endotype-directed tx @Rheumnow #EULAR2026 https://t.co/hB48aD7jx5
      πŸ’‰ Is Izokibep (Novel IL-17i) durable in PsA at 1yr?

      Phase2b/3 RCT: ~50% ACR50 at week in 343pts

      OP073 #EULAR2026 @R

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      πŸ’‰ Is Izokibep (Novel IL-17i) durable in PsA at 1yr? Phase2b/3 RCT: ~50% ACR50 at week in 343pts OP073 #EULAR2026 @RheumNow https://t.co/M3nrKFTA7c
      πŸ”¬ Does synovial biopsy-guided treatment outperform standard care in PsA?

      YES - 68% vs 45% DAPSA remission/LDA in 45p

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      πŸ”¬ Does synovial biopsy-guided treatment outperform standard care in PsA? YES - 68% vs 45% DAPSA remission/LDA in 45pts OP071 #EULAR2026 @RheumNow https://t.co/cLCR7I8QAm
      "the further I look back, the further I can see the future"

      Dennis McGonagle quoting Winston Churchill to describe his

      Aurelie Najm AurelieRheumo

      2 months ago
      "the further I look back, the further I can see the future" Dennis McGonagle quoting Winston Churchill to describe his approach to understanding What is New in PsA at #EULAR2026 @eular_org @RheumNow https://t.co/ayInzzb9lO
      Clinicians often come across the scenario of a patient with well-controlled spondyloarthritis where the ASDAS in the low disease activity range, CRP normalised, joints clinically quiet. However, the patient returns to the clinic still reporting significant pain. Their rheumatologist adjusts the biological, waits, returns. The pain persists.
      Over 70% of patients with PsA struggle with excess weight, amplifying synovio-entheseal inflammation and blunting biologic response. The rapid uptake of GLP-1RAs in rheumatology has raised an urgent mechanistic question: are clinical gains in PsA driven purely by weight reduction, or do these agents carry intrinsic anti-inflammatory properties? EULAR 2026 offered six abstracts that together illuminate, without fully resolving, this question.
      πŸ”Can early TNFi beat step-up csDMARDs in pSpA?

      SPARTACUS RCT (n=97) says YES
      60% vs 33% remission at 24 wks

      #EULAR2

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      πŸ”Can early TNFi beat step-up csDMARDs in pSpA? SPARTACUS RCT (n=97) says YES 60% vs 33% remission at 24 wks #EULAR2026 @rheumnow #OP0107 https://t.co/1odtcRdTLQ
      πŸ’‰ IXE+TZP beat IXE alone in obese PsA?

      YES - TOGETHER-PsA RCT
      33.5% vs 20.4% ACR50 at week 36 in 271 patients

      OP069

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      πŸ’‰ IXE+TZP beat IXE alone in obese PsA? YES - TOGETHER-PsA RCT 33.5% vs 20.4% ACR50 at week 36 in 271 patients OP069 #EULAR2026 @RheumNow @DrLauraCoates @AlexisOgdie https://t.co/orvAe38alc
      πŸ₯— Does diet improve PsA?

      DIPSA RCT: Mediterranean/DASH/Standard all improved DAPSA in 92pts

      Weight loss drove outco

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      πŸ₯— Does diet improve PsA? DIPSA RCT: Mediterranean/DASH/Standard all improved DAPSA in 92pts Weight loss drove outcomes OP070 #EULAR2026 @RheumNow https://t.co/k5y7bvDbDQ
      HLA-Cw6: a marker of more severe and difficult to manage psoriatic arthritis?

      POS0484
      #EULAR2026
      @RheumNow https://t.co

      Nelly ZIADE πŸ€ Nellziade

      2 months ago
      HLA-Cw6: a marker of more severe and difficult to manage psoriatic arthritis? POS0484 #EULAR2026 @RheumNow https://t.co/MIYZxuYT4v
      Psoriatic arthritis #PsA sessions raised important topics on intercepting arthritis in psoriasis, treating obesity as a

      Antoni Chan MD (Prof) synovialjoints

      2 months ago
      Psoriatic arthritis #PsA sessions raised important topics on intercepting arthritis in psoriasis, treating obesity as a disease target, synovial biopsy to guide treatment, molecular imaging to reveal subclinical disease. More tomorrow. #Rheumatology @RheumNow #EULAR2026
      Dietary interventions are rarely taken as seriously as pharmacological therapies in rheumatology. Yet patients ask about them constantly, and an increasing number of studies suggest that nutrition may influence disease outcomes. Two randomized controlled trials presented at EULAR 2026 add to this growing literature in PsA and RA. However, before we start prescribing Mediterranean diets, the data deserve a closer look.
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