Lupus

sheila RHEUMarampa
3 years 10 months ago
Pearl: Most oral lesions in #lupus are painless. The classic oral lesion is a lacy, reticular pattern superimposed on an erythematous plaque.
@RheumNow #ACR21 https://t.co/nxWnppxsZI


sheila RHEUMarampa
3 years 10 months ago
HZV in pts w/ #rheumatic dse by Dr CCMok et al
🔸Prevalence rates of HZV infxn (per 100py): SLE 1.7, RA 0.64, other RDs 0.76
🔸RFs assoc'd w/1st HZV infection
📌#SLE dx, serum albumin, serum creatinine; ⬆lympho/neutro ratio, CYC & Prednisolone use
@RheumNow #ACR21 abs0862 https://t.co/TXRmoBBDXK


Richard Conway RichardPAConway
3 years 10 months ago
Don't stop hydroxychloroquine in SLE, even when doing well. Associated with ⬆️flare risk. x2 even when in remission. Abstr#0959 #ACR21 @RheumNow https://t.co/1gGx0V5oxk


Janet Pope Janetbirdope
3 years 10 months ago
CV events go down when #hydroxychloroqine dose goes up in SLE BUT only in non smokers. Maybe due to smoking attention of HCQ levels &/or smoking as a bigger risk for CV over rides HCQ dose? ⬇️cardiac events by 28% in non-smokers abst0871 #ACR21 @RheumNow #RheumPix https://t.co/XxgK7iRXWi


Eric Dein ericdeinmd
3 years 10 months ago
#ACR21 Rheum Secrets and Pearl
Lupus pernio on the nasal ala.
⭐️Lupus in the name, but this is #sarcoid and not same as perniosis (chillblains)
@Rheumnow https://t.co/r49yjkjsje


Bella Mehta bella_mehta
3 years 10 months ago
Plenary at #ACR21 Renal outcome Risk of minority patients with pediatric #lupus @rheumnow abst#0956
inpatient hospitalizations. https://t.co/HK8w246Dsn


Eric Dein ericdeinmd
3 years 10 months ago
#ACR21 Rheum Secrets and Pearls
High CRP - not a typical marker of SLE flare. Look for infection!
@Rheumnow https://t.co/g1Z6OHvANv


sheila RHEUMarampa
3 years 10 months ago
Elevated CRP? Dr. Kolfenbach reminds us that it is not typical of #SLE flares, rule out INFECTION!
@RheumNow #ACR21 #RheumTwitter #MedTwitter https://t.co/FnkPdZ8gSl


TheDaoIndex KDAO2011
3 years 10 months ago
"We need to do more than improving quality of care to close the gap in racial disparities." - Dr. J Chang
Trends of adverse renal outcomes⬇️w/time in children hosp w/SLE. Improvements seen across racial/ethnic group, but black-white disparity persists abst#0956 #ACR21 @rheumnow https://t.co/HcOwQiKCb2


sheila RHEUMarampa
3 years 10 months ago
This slide 👇 from Dr. Mary Crow's lecture shows how 2 categories of autoantibodies with their distinct functions can allow for different therapeutic targets in #lupus
@RheumNow #ACR21 #rheumatology https://t.co/wkthvj21cE


Md Yuzaiful Md Yusof Yuz6Yusof
3 years 10 months ago
#ACR21 Hench Lecture. Wonderful talks by Peggy Crow on #lupus pathogenesis. Tour de force since LE cells discovery. Potential sources of self-nucleic acids:
💠Endogeneous retroelements LINE-1
💠Mitochondria
💠Cell-derived nuclear debris (NETs, apoptotic)
@RheumNow https://t.co/TSdyqblYaA


Dr. John Cush RheumNow
3 years 10 months ago
Great Hench Lecture from Peggy Crow at HSS! From LE Cell to Interferon: Deconstructing Lupus Pathogenesis
#ACR21 https://t.co/rUxiwKGFqm https://t.co/af2PKrFBv3


Janet Pope Janetbirdope
3 years 10 months ago
Obesity does not affect #SLE disease activity despite persistent ⬆️in CRP. From Toronto #lupus database #ACR21 abst#0864 @RheumNow https://t.co/4ZpAMaU0jk


Janet Pope Janetbirdope
3 years 10 months ago
Attaining low disease activity in #SLE ⬇️ mortality! More time in LLDAS = #lupus low disease activity state = ⬆️survival in >4000 pts with SLE. Also + was clinical remission on treatment CROT. Treat to a target has come to SLE @RheumNow #ACR21 abst0865 #ACRBest #RheumPix https://t.co/8ld8oncFRR


TheDaoIndex KDAO2011
3 years 10 months ago
Dr. P Crow #PhilipHench provides a tour of research on SLE pathogenesis:
👉discovery of Ab to small nuclear RNAs and the spliceosome
👉T cells' role on B cell differentiation
👉⬆️CD40L on SLE lymphocytes
👉IFN genes and their effects on the immune system #ACR21 @rheumnow https://t.co/6v9O19UUxX
