#ACR21 Abs:#1429: ALPN-303: Dual BAFF/APRIL antagonist for SLE: ⭐️Encouraging immunomodulatory activity and efficacy in animal models. ⬇️ Plasma cells and Ig secretions in vitro & vivo ⭐️Well-tolerated in animals w/o adverse events 🔥Phase 1 study in healthy volunteers! @Rheumnow