How concerned should we be for #hydroxychloroquine retinopathy. >4000 pts prospectively followed. 1/2 w RA & 15% w #SLE. New risks Asian with pericentral pattern and overall. Length of time on use and ⬆️wt based dose per day & CKD all risks. Abst#0989 #ACR21 #ACRBest @RheumNow https://t.co/XTfdQpVC7H

#ACR21 #Abstr0865 It’s time for T2T to achieve LLDAS in #lupus. In a study of N=2040 pts, mortality was 2.3% mainly due to infection. Remission off steroid was the best but only met in 14%. LLDAS-50 achieved in 48% pts and ⬇️mortality by 56% @RheumNow https://t.co/CddqMuFIOM https://t.co/g346Cbybep

• Lupus Low Disease Activity State Attainment Provides Significant Protection Aga…

#ACR21 #Abstr0864 How does obesity (BMI=/>30) affect #lupus outcomes? Data from Toronto showed: 💠⬆️hs-CRP 💠No in disease activity over 3yrs 💠⬆️CV events (combination of low grade inflammation + hypertension) @RheumNow https://t.co/IBu8uNSAJi https://t.co/2aqz5e3rwi

• Does Obesity Affect Disease Activity Outcomes in Systemic Lupus Erythematosus? …

Can patient with low dx activity SLE stop HCQ, or at least try and reduce the dose? Not if you want to avoid flares. If there are safer subgroups to try it in, we haven't found them yet (in fact higher dx activity➡️less risk ?other Rx) SLICC inception #ACR21 ABST0959 @RheumNow https://t.co/NS2V4dEGHv

Keep the Hydroxychloroquine! SLICC cohort eval flare risk in 1460 pts who⬇️or d/c HCQ: 👉pts in remission who d/c HCQ flared HR 2.77 (1.46,5.26) 👉pts in remission who⬇️dose flared HR 2.14 (1.34, 3.42) Abst#0959 #Plenary #ACR21 @rheumnow #ACRbest https://t.co/92U215s8IP

Do you order EKGs in everyone starting HCQ? Do you avoid HCQ in patients with heart failure? Will these abstracts impact your practice? Click on link to read more....#ACR21 @rheumnow #HCQ https://t.co/fvUZAvNWa8

• Dr. John Cush on Twitter: "Prolonging the Controversy of Hydroxychloroquin…

#ACR21 #Abstr0858 Petri reported effect of #COVID and vaccination in #lupus cohort 💠No increase in activity post-infection 💠⬇️cutaneous activity 💠⬆️ aCL IgG and IgM post-infection, 💠No increase in SLE activity or aCL abs post-vaccination @RheumNow https://t.co/iAaIfzf33c https://t.co/hA6sk6icrs

• Effect of COVID Infection and COVID Vaccination on SLE Activity, Including Anti…