You know you made it when you name appears on #ACRknowledgebowl @RheumNow #ACR21 on a question about who deveoped criteria for #AOSD https://t.co/VR5NQOfS3r

GOSH and NAC pedi CAPS pts study since 2005: anti-IL1 treatment has major impact on prevention and tx of CAPS symptoms. Observed by improved CAPS clinical dz activity scores; and normalized inflammatory markers. Abs 1110 #ACR21 #RheumNow @RheumNow https://t.co/xXrnVeRAq5

• Cryopyrin-associated Periodic Syndromes: GOSH and National Amyloidosis Centre E…

Hip involvement/TJR assoc'd w/ MEFV+ vs HLA-B27+ in FMF/SpA pts vs SpA. FMF/SpA: more severe disease, worse outcomes, & destructive hip involvement vs SpA, particularly in pts with MEFV variants & M694V homozygosity. Abs 1108 #ACR21 #RheumNow @RheumNow https://t.co/hlnN26AYgE https://t.co/1jHeVxKs7O

• More Frequent, Earlier Hip Involvement and Poor Outcome in Spondyloarthritis As…

Fautrel describes a series of 13 #AOSD (Stills) pts with Pulmonary arterial HTN (cath confirmed) - seen exclusively with women, 85% and all were on DMARDs - 31% MTX, 69% IL-1i, all on steroids- 5 deaths, 3 yr Survival 74% (same as PAH) #ACR21 Abstract 1100 https://t.co/qR21MdYG3A https://t.co/WN38ifgtT6

• https://bit.ly/3qiMuvi

#ACR21 #Abstr1100 Pulmonary Hypertension is a rare complication of AOSD. What can we learn from case-series of N=13🧐 💠All were female 💠Severe at diagnosis: mean PAP 41mmHg; 85% had NYHA III&IV 💠38.5% mortality rate So, plz be aware of PAH @RheumNow https://t.co/gmXF3AzH2n https://t.co/s5CXrHYUor

• Pulmonary Arterial Hypertension in Adult-Onset Still’s Disease: A Case Series o…

#ACR21 #Abstr1083 Do pts with Autoinflammatory disease flare differently during #COVID19? Survey of N=647 (mostly CAPS): 💠56% No change 💠Of pts who flared, 50% had low/absent fever 💠7% had COVID; mostly mild Shielding could influence results @RheumNow https://t.co/g7VazLfiT9 https://t.co/lzaSoMEzyR

• Outcomes of COVID-19 Illness in Systemic Autoinflammatory Diseases and Changes …

#ACR21 #Abstr1011 Can we differentiate NEMO-deleted exon 5 autoinflammatory syndrome (NEMO-NDAS) vs CANDLE? Bioinformatics to mask the IKBKG pseudogene is promising and identified IL-6, 8,18, IFN-I and TNF-induced cell death as future targets @RheumNow https://t.co/tR2PNymMVn https://t.co/yCKHQx6R3E

• Validation of Bioinformatics Pipeline to Detect NEMO-Deleted Exon 5 Autoinflamm…

Daniela Ospina Cardona presenting at the Down and Dirty 30 on VEXAS. Marked differences in mortality depending on exact mutation. Looking forward to hearing more about this at Plenary session III today #ACR21 @RheumNow https://t.co/R3gXpxOfSk