Articles By Jack Cush, MD
Don’t Hold the JAK (10.9.2026)
On this week's podcast, Dr. Jack Cush reviews the news: Steroids are easy to start and hard to stop; hold the MTX but not the biologic or JAK, weighing in on avacopan, and age-old messages for old-age patients.
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Don't Hold the Biologic or JAK with COVID-19 Vaccination
A randomized clinical trial in inflammatory arthritis arthritis shows that temporarily holding biologic or Janus kinase (JAK) inhibitor therapy at the time of COVID-19 vaccination is not warranted.
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Predicting and Preventing Psoriatic Arthritis
Psoriatic arthritis is often underdiagnosed in those with psoriasis (PsO), leading to diagnostic delays an undertreatment.
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POETYK PsA-1 - Efficacy and Safety of Deucravacitinib in Psoriatic Arthritis
van der Heijde et al have published the results of the phase 3 POETYK PsA-1 trial demonstrating that deucravacitinib was superior to placebo in clinical responses, patient-reported outcomes, and structural damage inhibition in patients with psoriatic arthritis (PsA).
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Exercise Can Improve Pain
This pooled meta-analyses (n=197,392) shows that exercise reduced pain versus control immediately after the intervention (SMD −0.59; 95% CI −0.65 to −0.53; P0.001). The benefit held across musculoskeletal, inflammatory, neurologic and cancer pain, and for every modality tested.
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Triple Hormone Receptor Agonist for Treatment of Obesity and Knee Osteoarthritis
The NEJM reports that retatrutide, an investigational incretin agent, was shown to yield up to 25% weight reduction, with subanalyses also showing reduced pain with knee osteoarthritis, and less apnea–hypopnea events in participants with obstructive sleep apnea.
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Remission – Believe it or Not (10.2.2026)
Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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Supervised Physiotherapy Wins after ACL Repair
The Annals of Internal Medicine has shown that chronic knee symptoms following anterior cruciate ligament reconstruction (ACLR) surgery is significantly lessened by a program of physiotherapist-supervised exercise therapy with education compared to single education and self-directed exer
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Link Between Obesity and Psoriatic Arthritis
Obesity is an incidental comorbidity in psoriatic arthritis (PsA). It is a modifiable, mechanistically active driver of disease onset, severity, and treatment failure. A new comprehensive review in RMD Open (Madsen et al., 2026) synthesizes 49 studies suggesting that weight management belongs in the core PsA treatment algorithm.
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Prednisone Primer for Patients
The Washington Post published a patient overview on "what Prednisone does to your body".
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