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Articles By Jack Cush, MD

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What's New in Lyme Disease

JAMA has published an overview of new considerations on Lyme disease, focusing on Diagnostics, Vaccines, and Prevention.

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POETYK PsA-1: Deucravacitinib in Biologic-Naïve PsA

POETYK PsA-1 trial tested the disease modifying efficacy of deucravacitinib, a tyrosine kinase 2 (TYK2) inhibitor, in psoriatic arthritis (PsA) patients and was shown to be superior vs to placebo for clinical responses, patient-reported outcomes, and structural damage inhibition in PsA.

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Mentshlichkeit* (8.7.2026)

Dr. Jack Cush reviews the news and recent journal reports on RheumNow.com.

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Rethinking Treatment of EGPA

Eosinophilic granulomatosis with polyangiitis (EGPA) has long been managed by extrapolating results from microscopic polyangiitis and granulomatosis with polyangiitis clinical trials. But new insights into EGPA's has lead to advances in therapy and new treatment paradigms.

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Top 20 Best Rheumatology Hospitals

U.S. News & World Report has published its Best Hospitals for 2026-2027, listing the best among many specialties, including rheumatology.  Each year U.S. News Best Hospitals ranked hospitals in the U.S.

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A Tribute to Daniel L. Kastner, MD, PhD (1951–2026)

The rheumatology, genetics and NIH communities mourn for Dr. Daniel L. Kastner, who died on July 28, 2026, in Bethesda, Maryland, at age 74. The following are declarations, tributes, and memories dedicated to this mensch of a man, titan of science, memorable mentor and humble physician.

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Arrhythmias in Autoimmune Rheumatic Disease

A new review in the Journal of Cardiovascular Development and Disease (Tamirisa et al) synthesizes how systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosis have an increased risk of arrhythmias and sudden cardiac death attributable to shared immune pathways.

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JAMA Review of Hip Fracture

The July 16th edition of JAMA reviews the highly prevalent problem of hip fractures - a major global health burden: 14.2 million occur worldwide annually (280,000 in the US), with global incidence higher in women (833.9/100,000) than men (510.0/100,000). Lifetime risk at age 50 is 22.9% for women, 10.7% for men. Mortality is substantial.

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Methotrexate Safety Tips (7.31.2026)

Dr. Jack Cush reviews the news and journal articles from this past week on RheumNow.com.

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Four Decades of Gout Management

During this month-long campaign on Gout, we have documented many significant changes in our approach to gout, as well as many unmet needs and deficiencies that merit our continued, primary attention.  We are all familiar with the famous 1905 quote, “Those who cannot remember the past are

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