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Articles By Jack Cush, MD

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Methotrexate intolerance in rheumatoid arthritis

A current large Rheumatoid arthritis (RA) cohort study from Cairo assessed methotrexate (MTX) use and found over half were MTX intolerant and a third of patients were noncompliant with MTX. 

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RheumNow Live Preview (1.30.2026)

Dr. Jack Cush reviews the news and journal reports from RheumNow.com - and the top 5 reasons to attend RheumNow Live 2026, which is one week away.

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Aortitis in Giant Cell Arteritis Treated with Tocilizumab

The The Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group studied giant cell arteritis with aortitis, comparing the efficacy of intravenous vs. subcutaneously (SC) tocilizumab (TCZ) - demonstrating the superiority of SC TCZ.

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Retractions in Rheumatology

Retraction of rheumatology studies is not uncommon; a recent analysis shows retractions have risen substantially.

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Difficult to Treat Rheumatoid Arthritis

Dr. Cush addresses the management of difficult-to-treat rheumatoid arthritis (D2TRA).

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DMARD Responses in Localized Scleroderma

JAMA Dermatology has published the results of a juvenile localized scleroderma (JLS) trial showing that mycophenolate mofetil (MMF) and methotrexate (MTX) are equally effective in treating JLS, noting low flare rates and possibly better tolerability with MMF.

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B Cells at the Brink in Sjögren Disease

The current issue of Arthritis & Rheumatology reviews current understanding of the immunopathogenesis of Sjögren disease (SjD) and how that has influenced the quest for drug development for this most systemic autoimmune disorder. 

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Treat-to-Target in Gout and Cardiovascular Outcomes

A 5 year JAMA study shows that a treat-to-target (serum urate < 6 mg/dL) study finds that effective urate-lowering treatment (ULT) results in a significantly reduced cardiovascular risk in patients with gout. 

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Trends in Rheumatoid Arthritis Mortality

A recent study examines trends in rheumatoid arthritis (RA)-related mortality among U.S. postmenopausal women (aged 55 and older). They found RA mortality rates have declined, yet disparities in who is most affected persist, especially for white women, and those over 85 yrs of age.

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Emergencies, Independence & Hemorrhage (1.23.2026)

Dr. Jack Cush reviews the news and reports from the past two weeks on RheumNow.Com

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