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Articles By Jack Cush, MD

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Shingles Risk with JAK Inhibitors and Other Biologics

By Jack Cush, MD
29 July 2021

Registry data suggests an increased risk of herpes zoster (HZ, shingles) in rheumatoid arthritis (RA) patients taking JAK inhibitors (JAKi) but also with other biologic DMARDs, compared to csDMARDs.

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No Cancer Risk with TNF Inhibitors in Rheumatoid Arthritis

By Jack Cush, MD
29 July 2021

The ARTIS Study Group has published their analysis of (non-skin) cancer risk in rheumatoid arthritis, claiming the overall safety of biologic DMARDs and targeted synthetic DMARDs (tsDMARDs).

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Combo Methotrexate and Leflunomide Safety in RA

By Jack Cush, MD
28 July 2021

Methotrexate and leflunomide (LEF) are the most widely prescribed DMARDs worldwide; yet biologic DMARDs are the newest and best selling agents for rheumatoid arthritis worldwide.

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Cardiovascular Prevention Lacking in Rheumatoid Arthritis

By Jack Cush, MD
28 July 2021

An increased cardiovascular disease (CVD) risk in rheumatoid arthritis is well known and feared but an RA cohort study suggests that preventive medication use in RA patients lags behind that seen in diabetes mellitus (DM).

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CDC Reverses Stance on Masks

By Jack Cush, MD
27 July 2021

Today the Centers for Disease Control and Prevention (CDC) said that masks should be used by those vaccinated against the coronavirus in public indoor spaces in parts of the country where the virus is surging.

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US News & World Report Ranks Best Rheumatology Hospitals

By Jack Cush, MD
27 July 2021

Medscape has published the annual U.S. News and World Reports ranking of Rheumatology Hospitals, again honoring Johns Hopkins Hospital with the top spot, with runner up status going to the Cleveland Clinic, Hospital for Special Surgery, Mayo Clinic and Brigham and Women's Hospital.

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Rheumatoid Poor Outcomes Not Linked to Comorbidity

By Jack Cush, MD
26 July 2021

Disease activity leads to poor outcomes; but does comorbidity add to this?  A recent analysis suggests that while comorbidities do not affect long-term, functional outcomes, sociodemographic factors do affect outcomes in rheumatoid Arthritis (RA).

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syringe, pill, DMARD, Treatment, therapy

DMARD Effects on COVID-19 Outcomes

By Jack Cush, MD
26 July 2021

Sparks and colleagues have published data from the Global Rheumatology Alliance noting that among rheumatoid arthritis (RA) patients afflicted with COVID-19 infection, there was little influence of their baseline biologic or targeted synthetic (b/ts) disease-modifying antirheumatic drugs (DMARDs)

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RheumNow Podcast – World Going to Pot (7.23.2021)

By Jack Cush, MD
23 July 2021

Bicycles, Tramadol, biologics - these are but a few of my favorites things in today's broadcast. Join me as I review the news and journal articles from this past week on RheumNow.com.

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Fracture Risk with Low Dose Steroid

By Jack Cush, MD
22 July 2021

A large RA cohort analysis shows that low-dose glucocorticoid therapy in rheumatoid arthritis (RA) patients may carry an increased risk of vertebral osteoporotic (OP) fractures. 

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