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Articles By Jack Cush, MD

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B Cell Depleters (2.21.2025)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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CRP and Hidradenitis Supprativa

A post hoc analysis of 2 phase 3 randomized clinical trials (PIONEER I and II)  of adalimumab vs Placebo in patients with active Hidradenitis suppurativa (HS) demonstrated more severe HS that was associated with elevated CRP had a higher BMI.

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Deucravacitinib in Psoriasis - 5 Year Outcomes

BMS released new five-year results from the POETYK PSO long-term extension (LTE) trial of deucravacitinib in treating patients with moderate-to-severe plaque psoriasis. The data was presented by Dr.

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myositis, polymyositis, wikipedia

Risk Prediction Modeling in MDA5 Dermatomyositis

Patients with Melanoma differentiation-associated gene 5 (MDA5) positive dermatomyositis (DM) are complicated and prone to interstitial lung disease, poor prognosis, and a high mortality.

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Targeting PD-1 in Rheumatoid Arthritis

The results of the large Phase 2b RENOIR trial showed that rosnilimab, a monoclonal antibody targeting PD-1, was effective in moderate-to-severe rheumatoid arthritis (RA) patients.

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AI,machine,learning

Growing Physician Enthusiasm for AI in Healthcare

The AMA has just published the results of a U.S. Physician survey and shown MD attitudes have positively shifted regarding the use of artificial intelligence (AI) in healthcare.

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Valentine RNL 2025 Review (2.14.2025)

Dr. Jack Cush reviews highlights from RheumNow Live 2025 held in Dallas, TX on Feb. 8-9, 2025.

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lupus SLE

Obinutuzumab Efficacy in Active Lupus Nephritis

A phase 3, randomized controlled trial of an anti-CD20 monoclonal antibody, obinutuzumab, was shown to be effective and safe in patients with active lupus nephritis.

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Drug Naming Games (2.7.2025)

Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.

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cannabis,weed,marijuana

Cannabis Hospitalizations and Mortality Risk

A Canadian population, retrospective cohort study shows individuals needing hospital-based (emergency department or hospitalization) care for a cannabis use disorder (CUD) were at increased risk of death. 

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