Adipokines in RA ⚡️Highest Quartile Adiponectin associated w/ ⬆️ all-cause mortality HR 1.46 ⬆️ CV mortality HR 1.85 ⚡️Highest Quartile Leptine ⬆️ 25% all-cause mortality #ACR21 #Abst1645 @RheumNow https://t.co/O1NAbfMvif https://t.co/VVdgZHP1j5

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How do RA pts go with ICI cancer therapy? @VUMCRheum audit reflects overall prev experience: - approx 50% flare (?some reflect DMARD W/H) - flares overwhelmingly managable - few (1/19 here) cease ICI due to RA flare RA pts deserve best cancer Rx too!! #ACR21 ABST1523 @RheumNow

Dr. Despotovic shares general principles about ICU admissions in patients w/ #rheumatic disease. 🔺#SLE, RA, systemic #vasculitis, SSc, IIMs 🔺serologic testing useful but interpret w/n clinical context @RheumNow #ACR21 https://t.co/jb3Mt31dZz

#ACR21 Thieves! TM11. Belly pain in patient with RA nodules: ⭐️ A: rheumatoid nodulosis of pancreas and duodenum. Great case! @Rheumnow https://t.co/PuO4tka3FJ

Sub-analysis of ICHIBAN study looking at adverse events in tocilizumab treated patients with/without steroids. Steroids associated with small increase in adverse events across board. Abstr#1693 #ACR21 @RheumNow https://t.co/ldiovirKpo

Meta-analysis of PUFA supplementation in RA. Apparent benefits across most measures, albeit often small. Abstr#1682 #ACR21 @RheumNow https://t.co/1rGhpqvJvp

GLORIA study of adding prednisolone 5mg to DMARDs over 2 years for RA in those >65 years. Mean DAS 0.37 points lower, Sharp score 1.7 lower (are either of these clinically significant?). NNH 9.5. To me causing harm chasing statistical benefit Abstr#1678 #ACR21 @RheumNow #ACRBest https://t.co/KYk1II3J3w

I don't know much about antifibrotics in RA-ILD, but these data emphasise that HRCT pattern matters My simple mind, for any disease: multiple subtypes with different trajectories➡️likely to be differing responses to Rx TRAIL1: pirfenidone in RA-ILD #ACR21 ABSTL10 @RheumNow https://t.co/v7HCO0ZBe1

Comparative effects of abatacept in RA-ILD with UIP/NSIP. Appears equally effective in stabilising FVC, DLCO, and HRCT findings in both. Abstr#1683 #ACR21 @RheumNow https://t.co/l0Ia1D9c56