ADACTA & MONARCH both showed IL6i monoRx > TNFi monoRx for RA in DBRCTs. What about in real-world data? Looking at CorEvitas, less so LDA: aOR 0.99 MCID in CDAI: 1.06 Even without MTX, both great drug classes for RA Equally so? #ACR21 ABST0834 @RheumNow https://t.co/6wvzVrXTW6 https://t.co/fYEktJhZuV

• https://meet.acrconvergence.org/meetings/virtual/dSEeRFsuxifj8bZbz

In Australia, there's free choice of originator vs biosimilar for etanercept. Real-world data shows exactly what you'd expect over >48 months - and sometimes it's what you expect that's exactly what you want to see... OPAL data #ACR21 0840 @RheumNow https://t.co/YJA2Cua9cw

#ACR21 Abst#0910 by @rheum_cat. Do TNFi ⬆️ risk of incident HTN in AxSpa? ⭐️PSOAS cohort: Prosp study from 2003-2018 ▶️When adjusted for confounders (obesity, disease activity, NSAID use), insufficient evidence to show ⬆️ risk of HTN w TNFi https://t.co/DCZ3W8CkOa @Rheumnow

• https://bit.ly/3ESM4ji

TNFi + JIA = watch the skin! A nearly 3fold increase of paradoxal psoriasis in JIA patients exposed to TNFi reported in the CARRA registry w/ incidence rate the highest on children receiving adalimumab. #Abst0241 @RheumNow #ACR2021 https://t.co/uXOwV2RlGu https://t.co/8f8mvVUkV2

• Psoriasis Rate Is Increased by the Exposure to TNF Inhibition in Children with …

⁦@JointMD⁩ shares his thoughts on IL23, IL17, TNF inh- where/when/how we might use them. ⁦@RheumNow⁩ #acr21 https://t.co/mVw05iFPhF

• PsA Perspectives - IL-23: Dr. Eric Ruderman - YouTube

2 year study of AxSpA pts in clinical remission who tapered TNFi. ⭐️52% successfully tapered to either 2/3, 1/2 or 1/3 dose ⭐️Baseline physician global score independent predictor of successful tapering Abs#364 #ACR21 @RheumNow https://t.co/9Kti5JGMYr https://t.co/y1Uj2dTABC

• Dose Tapering of TNF Inhibitors in Patients with Axial Spondyloarthritis in Rou…

#ACR21 #ACR2021 Rheumatology Reproductive Health 👉🏻 Biologics and breast milk 👉🏻 Good vaccine response with TNFi (like with covid vaccines ) 👉🏻 ustekimumab seems safe in pregnancy 👉🏻 Tofacitinib/ small molecules may cross placenta/ be in breast milk ➡️ contraindicated in preg/BF https://t.co/qk3sLR4QHz