Richard Conway RichardPAConway
            3 years 11 months ago 
          
         
          Patients with acute calcium pyrophosphate arthritis at ⬆️risk of cardiovascular events. Abstr#1898 #ACR21 @RheumNow https://t.co/IOFYJnutHM
        
        
  Janet Pope Janetbirdope
            3 years 11 months ago 
          
         
          Why would higher active dose of #methotrexate with sc admin & more metabolites polyglutamates which can give side effects have LESS AEs?  Never understood it! #ACR21 abst#1695 @RheumNow https://t.co/qrEKofX1cl
        
        
      
  Olga Petryna DrPetryna
            3 years 11 months ago 
          
         
          Abst1810 #acr21 @RheumNow survey of pt preferred meds for PsA points out ⬆️ interest in IL17 & PDE4 since 2018 guideline update: anti-IL17 compared to 2018 or earlier (30% vs 3.5% p< 0.001);anti-PDE4 (40% vs 11.5% p< 0.012). Meds SEs& prevention of joint damage important for pts
        
        
  Eric Dein ericdeinmd
            3 years 11 months ago 
          
         
          #ACR21 L16 - Breakthrough #COVID19 in rheum pts
⭐️Breakthrough ifn ~4%, compared to 3% wo rheum disease. Statistically signif ⬆️ risk in RA, gout, polymyositis, vasculitis, multiple rheum disease
⭐️bDMARD, multiple AIRD risks
@Rheumnow https://t.co/cuM9LcEr4u https://t.co/Los2n7BoIn
        
        
      
  Robert B Chao, MD doctorRBC
            3 years 11 months ago 
          
         
          After 2018 ACR Guidelines, significant increase in IL-17i and PDE4i use in PsA pts
⭐️TNFi most common tx
⭐️28% pts not on any tx⭐️
#ACR21 @RheumNow Abs#1810
https://t.co/7Rmirfm3nK https://t.co/0Ui9pq5uyo
        
        
      
  Dr. Rachel Tate uptoTate
            3 years 11 months ago 
          
         
          RHEKISS registry: SpA pts on bDMARDs at conception are NOT at inc. risk for adverse pregnancy outcomes. Discontinuation of bDMARDs after conception is assoc'd w/ inc. dz activity during/after pregnancy & flare risk. Abs 1730 #ACR21 #RheumNow @RheumNow https://t.co/b2wI9GZios https://t.co/wsuvv3hF0v
        
        
      
  Janet Pope Janetbirdope
            3 years 11 months ago 
          
        The plague protection genetically can lead to Pyrin induced inflammasome activation. Theory of more FMF in Mediterranean / Turkey. So high protection gene in population Dan Kastner - a genetic detective 9T119 #ACR21 #ACRBest @RheumNow https://t.co/qzdc12fT0j
  Dr. Antoni Chan synovialjoints
            3 years 11 months ago 
          
         
          In Phase 2 trial of Tildrakizumab in active PsA efficacy tended to be lower among patients with comorbid MetS, with improvements from baseline across efficacy measures generally larger in patients without MetS vs those with MetS @RheumNow #ACR21 Abst#1819 https://t.co/ATxaFz9X2O https://t.co/2iJMNmfUzg
        
        
      
  sheila RHEUMarampa
            3 years 11 months ago 
          
         
          Post hoc analysis of pooled data from 19 clin trials on SEC & CV risk & systemic #inflammation in PsO, PsA, AS
📌Traditional CV parameters remained stable on all SEC treated grps
📌SEC sig. ⬇hsCRP & NLR
@RheumNow #ACR21 abs1835 https://t.co/iCaGFbXNXn
        
        
  Dr. Rachel Tate uptoTate
            3 years 11 months ago 
          
         
          French study shows more than 75% of RA/SpA pregnancies resulted in a live-birth, BUT 50% of pts had at least one unfavorable pregnancy outcome! However, miscarriage prevalence lower than in reported literature. Abs 1724 #ACR21 #RheumNow @RheumNow https://t.co/64PspIKPTu https://t.co/LyfHVARAgd
        
        
      
  David Liew drdavidliew
            3 years 11 months ago 
          
         
          IVIG can passively transfer donor Ab including 'clinically significant' e.g. HBcAb
@OchsnerHospMed 123 pts HBcAb+ post-IVIG
37 had HBcAb- captured pre-IVIG
of those, 22 received prob unnecessary antiviral Rx
Be smart: pre-IVIG, anticipate - test HBV
#ACR21 ABST1528 @RheumNow
        
        
  Robert B Chao, MD doctorRBC
            3 years 11 months ago 
          
         
          2 year study shows low rates of radiographic progression in PsA pts on guselkumab 
#ACR21 @RheumNow Abs#1805
https://t.co/dobg3cEXXG https://t.co/m1P24qPAhy
        
        
      
  Pedro Castillo _Castillo_Pedro
            3 years 11 months ago 
          
         
          SERENA interim analysis on interruption of secukinumab in AS and PsA
🔹>=16 wks of Rx before interruption of >= 3 mo.
🔹75-80% of pts reinitiated w/o loading phase
🔹AS: BASDAI, PGA stable
🔹PsA: SJC, TJC returned to Rx baseline
https://t.co/3G6rVW8TPv
#ACR21 Abst#1361 @RheumNow
        
        
      
  Dr. Rachel Tate uptoTate
            3 years 11 months ago 
          
         
          Have you heard of pSpA? (Peripheral) pSpA: distinct clinical phenotype w/ intermediate features between pure PsA & pure axSpA but w/ a higher disease burden compared to both diseases, & lower use of b-DMARDs. Abs 1787 #ACR21 #ACRbest #RheumNow @RheumNow https://t.co/Wsysm7A0Y3 https://t.co/rwQ8ukBEDq
        
        
      
  Janet Pope Janetbirdope
            3 years 11 months ago 
          
         
          Genes for oral aphthous ulcers common in gen pop’n, Behcets and w auto inflammatory PFAPA - kids w fevers ⬆️IL12 Kastner practical gene stories @RheumNow #ACR21 9T119. Have a listen. Bench to bedside & back https://t.co/UkPzoYbBNb
        
        
  

   
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