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What's Hot
RheumNow Rheumatology Roundup: Drs. Kavanaugh and Cush
Rheumatology Roundup! Drs. Cush and Kavanaugh convene for their annual impromptu review of some of the best and more interesting abstracts presented at ACR 2021.
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TNF Inhibitor Panel Discussion: ACR21 Annual Meeting
RheumNow TNFi faculty convened to discuss several TNFi-related abstracts presented at ACR 21. Panelists: Drs. Aurelie Najm, Janet Pope, David Liew, Eric Dein and Swetha Alexander.
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Spondyloarthritis Panel Discussion: ACR21 Meeting
Panelists: Drs. Antoni Chan, Robert Chao, Rachel Tate, Sheila Reyes and Akhil Sood. Abstracts discussed include #0562, #1919, #0907, #0364 and #0919
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Might Tofacitinib Reduce Malignancy Risk with Patients with RA? Dr. Jonathan Kay
Dr. Kay discusses abstract 1940 and abstract 980 presented at the ACR21 annual meeting.
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Diagnosing (Bad) VEXAS: The Experts Speak Drs. Beck and Ferrada
Dr. Cush discusses Dr. Marcela Ferrada and Dr. David Beck to discuss VEXAS syndrome and abstract 1426, which was presented at the ACR21 annual meeting.
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Pediatric Psoriatic Arthritis: Dr. Eric Ruderman
Dr. Ruderman discusses abstracts #1424 presented at the ACR21 annual meeting.
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Urine Proteome Advances: What Do They Mean? Dr. Michelle Petri
Dr. Petri reviews abstracts #1422 and #1936, presented at the ACR21 annual meeting.
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ACR21 Day 3 Recap: Polypharmacy, New Lupus Drugs, VEXAS, Safety Data
Blurb: Drs. Jack Cush and the RheumNow Faculty Drs. Akhil Sood, Antoni Chan, Olga Petryna and Eric Dein, discuss highlights from Day 3 (Monday) at the ACR21 annual meeting. Abstracts include #1367, #1044, #1444, #1083 and more.
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Cardiovascular Disease for TNFi vs JAKi: Dr Jon Giles
Dr. Giles discusses abstracts #0831and #0958 presented at the ACR21 annual meeting.
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Predictors of TNF Response with Drs. Pope, Dein and Liew
Drs. Janet Pope, David Liew and Eric Dein discuss TNF data presented at the ACR21 annual meeting, including abstracts #1251, #1442, #1448.
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Caring for the Older Patient with Rheumatic Disease: Drs. Makris, Yung and Dao
Drs. Kathryn Dao, Una Makris and Raymond Yung discuss the field of geriatric rheumatology and caring for the older patient with rheumatic disease.
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Autoinflammatory: PAH in AOSD, VEXAS, JAKi in Still's, Role of labs in infections vs. flares
Drs. Jack Cush, Yuz Yusof, Bella Mehta, Olga Petryna and Rachel Tate review autoinflammatory data presented at the ACR21 annual meeting, including abstracts #1100, #1062, #1426, #0252, #0195, and #1083.
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FDA Session Review: Dr. Arthur Kavanaugh
Dr. Kavanaugh discussed the FDA session presented at the ACR21 annual meeting, including safety data and new approvals and indications in several rheumatic diseases, including lupus, ANCA-associated vasculitis, lupus nephritis and more.
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The Respiratory Tract and RA with Drs. Sparks, McDermott and Kronzer
Drs. Jeffrey Sparks, Greg McDermott and Vanessa Kronzer discuss work in the area of respiratory disease in RA, mucosal paradigm, RA-ILD, bronchiectasis, as well as their experience as virtual attendees at the ACR21 annual meeting.
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Pulmonary Hypertension in Adult Onset Still's Disease: Dr. Jack Cush
Dr. Cush reviews poster #1100 presented at the ACR21 annual meeting.
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Data on Existing SLE Medications, Patient Centered Outcomes, and Exercise: Dr. Michelle Petri
Dr. Petri discusses data on existing SLE medications, patient-centered outcomes and the importance of exercise, presented Monday at the ACR21 annual meeting.
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ACR21 Day 2 Recap: CV Risk, Tapering in SpA, Microbiome in PsA, Vit D
Drs. Jack Cush and the RheumNow Faculty Drs. David Liew, Swetha Ann Alexander, Meral El Ramahi, Mrinalini Dey and Robert Chao, discuss highlights from Day 2 (Sunday) at the ACR21 Virtual meeting.
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TheDaoIndex KDAO2011
4 years ago
Dr. R Thomas: current studies on prevention of RA:
👉oral DMARDS (MTX, HCQ)
👉biologics (RTX, abatacept)
👉 studies regulating T cells to restore tolerance
👉biomarkers of tolerant state & look at people who don't develop RA
👉 imaging as window of subclin dz. #ACR21 @rheumnow https://t.co/5bsu5459az
Eric Dein ericdeinmd
4 years ago
#ACR21 Abs#0818: Starting biologics in moderate vs severe RA activity:
▶️ Moderate disease activity: more likely to reach LDA, remission
▶️ Severe disease: greater overall improvements, but less likely to reach remission
https://t.co/9jBtN9wUGF @Rheumnow
Richard Conway RichardPAConway
4 years ago
Tocilizumab biosimilar study. Pharmacokinetic and pharmacodynamic bioequivalence. Delighted to see this, we really need a toc biosimilar after the negative impact of supply shortages of Actemra/Roactemra this year on patients. Abstr#0823 #ACR21 @RheumNow https://t.co/MMVCwaar3r
Despite the increasing scientific knowledge on axSpAs, a substantial gap still remains. Delay in diagnosis continues to pose a threat in the early identification of patients and those already on treatment may deal with additional issues such as work productivity or quality of life.
Mrinalini Dey DrMiniDey
4 years ago
How useful are validated #PROMs in remote monitoring?
Abs#0746 Remote patient-completed assessments of disease activity may be useful in #telehealth settings- a study looking at single-item and scale measures.
#ACR21 @RheumNow
https://t.co/Xr6pqJy91q https://t.co/PKAugkgNzU
David Liew drdavidliew
4 years ago
So it's day 2 at #ACR21, and you know what that means - it's ORAL Surveillance day!
This is the figure everyone will be talking about, leading up to details in the plenary.
Why are the other bars higher than the pink bars?
ABST0831
plenty of @RheumNow coverage coming on this https://t.co/B80cSmhNV7
Eric Dein ericdeinmd
4 years ago
Abst#0788 #ACR21. Forgot to measure vitamin D?
▶️ Red cell distribution width (RDW) inversely correlates w vit D 25(OH) levels prior to MTX
⭐️ RDW ⬆️ after starting MTX, no longer correlates
https://t.co/b5EPDmGE18 @Rheumnow https://t.co/cNN14ErOmF
David Liew drdavidliew
4 years ago
ORAL Surveillance
In mod-severe RA pts >50yo, with CV RF & no hx malignancy, patient-years of exposure required for one event (vs TNFi):
MACE
tofa 5mg bid: 567
tofa 10mg bid: 319
malignancy
tofa 5mg bid: 276
tofa 10mg bid: 275
#ACR21 ABST0831 @RheumNow https://t.co/9vyXPTMFzj
Eric Dein ericdeinmd
4 years ago
#ACR21 Abst#0793. Japanese multicenter US cohort (KUDOS) study, looked at difficult to treat (D2T) RA pts
▶️ 1/5 pts are D2T (fail 2+ b/tsDMARD, mod disease or GCs)
⭐️ Contributors of good outcomes: IL-6i (OR 9.6), concomitant MTX (OR 7.1)
@Rheumnow https://t.co/9YSa4ebQlR
Mrinalini Dey DrMiniDey
4 years ago
Greater #comorbidity burden is assoc. w/ worse improvement and disease activity in 1st yr of treatment in ERA @earlyarthritis.
Comorbidities esp affect SJC and patient and physician global assessments.
#ACR21 Abs#0798 @RheumNow
https://t.co/02BRqYp9Yk
Eric Dein ericdeinmd
4 years ago
#ACR21 Abst#0801 Early remission at 6 mos is a predictor of long-term remission in patients w new onset RA
▶️ DAS28-CRP, SDAI, CDAI at 6mo predicted remission at 60 months
https://t.co/vWy7EmseZp @Rheumnow https://t.co/HWJSjvFY8d
Janet Pope Janetbirdope
4 years ago
Good news for #COVID vaccine in #SLE. ✅doesn’t cause #lupus flares ➡️ no increase in APS. What about #SARS-CoV2 infection in SLE. Flares ↔️ stable but ⬆️APS Abs. from Hopkins cohort. Petri #ACRBest #ACR21 abst0858 @RheumNow https://t.co/ABx4C4lwvs
Podcasts
Giant Cell Arteritis and Polymyalgia Rheumatic Wrapup: Drs. Calabrese, Liew, Conway and Mackie00:20:18 -
Reproductive Health in Rheumatic Diseases: Drs. Bermas, Buyon and Dao
00:20:26 -
The Expert Gout Panel with Drs. Neogi, Saag, Pillinger, Cush and O'Dell
00:35:26
Poster Hall