Slick poster, but must be careful w/real world data. Big risk of confounding/channeling bias Pts with MACE risk (not always well-characterized by ICD codes) also less likely to receive JAK & therefore less liekly to have subsequent MACE #ACR24 @RheumNow Abstr#1394 https://t.co/lilU0byJ1s

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Getting more data on using deucravacitinib for PsO/PsA manifestations Impressive effect on scalp psoriasis (which often means a lot to patients) Given how safe it is, it's increasingly tempting to use more of it in mild-mod PsA #ACR24 PSORIATYK SCALP trial ABST1137 @RheumNow https://t.co/vxS3RSlIN0

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What do current national/international rheumatology association guidelines say about perioperative discontinuation of biologics? it's highly, highly variable no wonder people get confused! #ACR24 ABST1037 @CatherineL_Hill @RheumNow https://t.co/cmJ3qKU1QT

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Serrano-Combarro et al. Case series of upadacitinib in RA-ILD. 18 patients. Report stable/improved dyspnoea and HRCT over 12 months. PFTs shown, relatively stable @RheumNow #ACR24 Abstr#1372 https://t.co/yncy0lPq60 https://t.co/mrDMtEDwUt

• Upadacitinib and Other JAK Inhibitors in the Treatment of Rheumatoid Arthritis …
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Great table re:side effects of even low dose steroids in RA Likely generalizes to other diseases ie PMR, SLE P in prednisone stands for poison! #ACR24 @RheumNow https://t.co/0opDEtzm9E

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Petri recommends IM triamcinolone as safer than prednisone dosing per FLOAT trial, decreased risk of fx @RheumNow #ACR24 @jhrheumatology https://t.co/vhMRdSkBAA https://t.co/novlGcss6x

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Late-onset asthma but earlier EGPA diagnosis? Abstract 1604 used IQVIA data to develop a machine learning model for better EGPA dx. Key predictors included eosinophilia, asthma, chronic sinusitis, multiple CXRs, skin biopsies, and GC prescriptions. @RheumNow #ACR24

Sukumaran et al. Does does of IA steroid matter in knee injection? RCT 30 patients. Triamcinolone. 6-week WOMAC decrease 6% in 10mg, 10% in 20mg , 29% in 40mg @RheumNow #ACR24 Abstr#1186 https://t.co/WUYiEP5dSo

• Intra-articular Corticosteroid Injections for Knee Osteoarthritis: Does the Dos…

Exciting early data for new highly selective TYK2i zasocitinib Improved PASI skin scores (though not as much as IL23i...) Funky skin-related adverse events at higher doses, not sure what to make of that? #ACR24 @rheumnow Abstr#1477 https://t.co/CtOFsoHdBh

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Reset the bar for remission (off steroids)!! Session #17S19 3% higher risk of organ damage for each 1mg of pred Remission possible in rheum with lower dose GC regimen and faster taper #GCStewardship #ACR24 @RheumNow @BethIWallace

In case you needed more encouragement for recombinant zoster vaccination in RA patients: it prevents herpes zoster episodes, in the real world. RA pts in KP system n=1926 vaccinated matched 1:3 with non-vaccinated - HZ reduced 60% - PHN reduced 88% #ACR24 ABST0977 @RheumNow https://t.co/BryBrlv9K5

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Petri on Steroids in SLE Steroid-related organ damage presents later - organ damage is higher in African-Americans Dose response for prednisone and CVD risk Each 1 mg prednisone = 3% increase risk in organ damage! #ACR24 @jhrheumatology @RheumNow https://t.co/00S1mxrXJp

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John Stone Steroid-free AAV CYCLOPS: steroid tox like “wallpaper on room” WGET (ETN for GCA) - taper off by 6 mos - neg trial but started tapers RAVE - low doses 8-9 mg/d over 18 mos LoVAS - low dose steroid equally eff ADVOCATE - AVA one month taper, tox score #ACR24 @RheumNow https://t.co/C7eLK5UNPM

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Biosimilar changes ASP outpacing reimbursement making not affordable to use Working with CMS but needs further legislation to fix this FDA may change interchangeability status for medications to no longer require switching studies @ACRheumDC @RheumNow #ACR24 https://t.co/daYQJvsHRG

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Regulatory update @ACRheumDC Inflation Reduction Planned decrease in 10 drug prices including ETN Expect this may be gutted by new administration. Will follow and advocate for drug pricing @RheumNow #ACR24 https://t.co/ZrcMaLD6tu

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