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Drug Safety

      @LennMcD @ACRheumDC

      Do policies affect medication access, costs, reimbursements, telehealth, or your life as a rheumat

      Eric Dein ericdeinmd

      10 months 3 weeks ago
      @LennMcD @ACRheumDC Do policies affect medication access, costs, reimbursements, telehealth, or your life as a rheumatology provider or patients? Contact - quick and easy! https://t.co/TvMlXiIZQR @RheumNow #ACR24 https://t.co/plnUtl7Kml https://t.co/lFGx7hzlKy
      @LennMcD @ACRheumDC
      Current congress (118th) - very tight margins, paralyzed by the ‘24 elections. Now in lame duck

      M

      Eric Dein ericdeinmd

      10 months 3 weeks ago
      @LennMcD @ACRheumDC Current congress (118th) - very tight margins, paralyzed by the ‘24 elections. Now in lame duck Many ACR policies made into bills - PA, step rx, copay accumulator, workforce, loan repayment, incr Rx transparency Needs to be passed into law @RheumNow #ACR24 https://t.co/1elEUiUAmh
      The SELECT-GCA study, looking at upadacitinib in GCA, anchored the ACR 2024 opening plenary for a reason - it is highly notable and badly needed.
      Day 1 Recap at ACR24
      Phase 2 DBRCT of daxdilimab, an immunoglobulin-like transcript 7 to target plasmacytoid dendritic cells

      No difference i

      Mike Putman EBRheum

      10 months 3 weeks ago
      Phase 2 DBRCT of daxdilimab, an immunoglobulin-like transcript 7 to target plasmacytoid dendritic cells No difference in primary outcome... but kiiiinda looks like something there? I dislike Phase 2's; should go straight to Phase 3 if able #ACR24 @rheumnow Abstr#1542 https://t.co/osDWDskfnA
      @KDAO2011 help me out here; what is the point of analyses like this?

      NO difference in PROs comparing voclo vs plbo...

      Mike Putman EBRheum

      10 months 3 weeks ago
      @KDAO2011 help me out here; what is the point of analyses like this? NO difference in PROs comparing voclo vs plbo... ...but if you split by responder status its different Prescribing the drug doesn't help PROs, but when it works it works? 🤔 #ACR @RheumNow Abstr#1538 https://t.co/339drHwUuK
      This is very true. We showed a number of years ago that patients with gout have increased platelet activation at baselin

      Richard Conway RichardPAConway

      10 months 3 weeks ago
      This is very true. We showed a number of years ago that patients with gout have increased platelet activation at baseline, which then dramatically increases during flare. Treating gout properly may ameliorate this. #ACR24 @RheumNow https://t.co/VL8fy3ezjx https://t.co/9XdrG1NG9c
      Factors associated w/ secukinumab response in PsA?

      Analysis of 2.7k pt in EuroSpA

      Associated w/ favorable response

      Brian Jaros, MD Dr_Brian_MD

      10 months 3 weeks ago
      Factors associated w/ secukinumab response in PsA? Analysis of 2.7k pt in EuroSpA Associated w/ favorable response ❗️elevated CRP >10 mg/L ❗️fewer prev tx Associated w/ lower response: ❗️smoking ❗️higher patient global score / HAQ @RheumNow #ACR24 Abstr 2325
      ACR Convergence 2024 opened today with a full slate of presentations, posters and specialty meetings.  The meeting began with a flip: the plenary sessions started at 9AM and the poster session began at 1030 AM. Below are some of the highlights from day one in Washington, DC.
      New data to guide role of long-term, low dose GC in GPA

      Active GPA s/p tx -> randomized to d/c pred within 1 mo or s

      Brian Jaros, MD Dr_Brian_MD

      10 months 3 weeks ago
      New data to guide role of long-term, low dose GC in GPA Active GPA s/p tx -> randomized to d/c pred within 1 mo or stay on 5mg daily Fewer relapses on 5mg pred but w/qualifications: 👉 most flares = minor 👉 no difference in flares if RTX on board @RheumNow #ACR24 Abst 0774 https://t.co/Jvc40QWLqM
      Challener et al. TriNetX study. 32,000 patients. SGLT2i reduce need for gout visits (HR 0.94) ULT initiation (HR 0.69) a

      Richard Conway RichardPAConway

      10 months 3 weeks ago
      Challener et al. TriNetX study. 32,000 patients. SGLT2i reduce need for gout visits (HR 0.94) ULT initiation (HR 0.69) and colchicine (HR 0.82). I worry about the discordant rates, ULT initiation much lower. @RheumNow #ACR24 Abstr#0848 https://t.co/VTKHMmDEKV https://t.co/C2opiDmBXx
      🤵‍♂️Results from BACHELOR

      ➡️34 PMR pts
      ➡️18 BARI, 16 PBO
      ➡️Primary endpoint: CRP PMR-AS≤10 w/o o

      Mrinalini Dey DrMiniDey

      10 months 3 weeks ago
      🤵‍♂️Results from BACHELOR ➡️34 PMR pts ➡️18 BARI, 16 PBO ➡️Primary endpoint: CRP PMR-AS≤10 w/o oral GC rescue from W0 to 12 78% BARI pts reached primary endpoint vs 13% PBO No new safety signals BARI 4mg 12W, then 2mg 12W➡️36W low disease activity in PMR Ab0858 #ACR24 @RheumNow
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