Psoriatic arthritis

Caoilfhionn Connolly CaoilfhionnMD
10 months 3 weeks ago
#1456
💥In a real-world UK PsA cohort, 25% had joint erosion @ diagnosis
➡️Mean disease duration 34mo. @ diagnosis
➡️Mean disability score = mod. to severe
💥Delay in diagnosis=poor outcomes
‼️Are we doing enough to catch PsA early? ?
🔑Earlier detection key
#ACR @RheumNow

Caoilfhionn Connolly CaoilfhionnMD
10 months 3 weeks ago
#1474
🔬Severe PsA? Guselkumab (GUS) has promise!
➡️In bionaive pts with severe disease activity,
GUS v. PBO resulted in:
🔴73% improvement in joints
🔴53% lower disease activity
🔴63% better PtGA by 2 years
➡️Rapid results by W2, sustained through W100.
#ACR @RheumNow

Caoilfhionn Connolly CaoilfhionnMD
10 months 3 weeks ago
#1326
🔬 Predicting Imminent Inflammatory Arthritis
➡️543 anti-CCP+ at-risk (high/low) tracked
🔑Predictors for IA in high-risk:
🔴EMS≥30min(OR 11)
🔴RF+(OR 6)
🔴US PD(OR 5)
🔴smJTC (OR 5)
🔑Predictors for IA in low risk:
🔴RF+(OR 8)
🔴Anti CCP >3xULN(OR 7)
#ACR24 @RheumNow https://t.co/ou9HNcNb8X


Janet Pope Janetbirdope
10 months 3 weeks ago
Half of the respondents chose #IL17i for #psoriatic #arthritis #PsA Rx for #Achilles #tendonitis
Interesting as lots
Of data
On #enthesitis wIL23i
Likely all
Effective #PsA Rx helps #tenosynovitis
some have
➡️ data on #efficacy
⬆️ bio rationale
#ACR24 @RheumNow @ACRheum https://t.co/wzefjsfdaj

Adela Castro AdelaCastro222
10 months 3 weeks ago
@DrLauraCoates presented Sex differences in clinical presentations of PsA:
-Women present >polyarthritis, enthesitis and worse PROs which translates to ⬆️ DAPSAs in spite of less Rx progression.
-Men more oligoarthritis, axial involvement, higher skin disease.
#ACR24… https://t.co/iapZF0nZWX https://t.co/jZ79WfxZwh


Caoilfhionn Connolly CaoilfhionnMD
10 months 3 weeks ago
🔥Sex matters in PsA
🔑Differences in :
➡️clinical phenotypes
➡️radiographic progression
➡️disease impact
➡️pt perception of disease
➡️response to Rx
#ACR24 @RheumNow https://t.co/iOXQmoxgp0


Adela Castro AdelaCastro222
10 months 3 weeks ago
The 3-4-5 rule for positive MRI in axSpA remains.
The MRI lesion cut-offs demonstrated high performance across different features of axSpA (PsO, AAU,IBD).
Deep fat and deep sclerosis high specificity for axSpA.
#Abst0821 #ACR24 @RheumNow https://t.co/4JM5MHrB8z


Brian Jaros, MD Dr_Brian_MD
10 months 3 weeks ago
Factors associated w/ secukinumab response in PsA?
Analysis of 2.7k pt in EuroSpA
Associated w/ favorable response
❗️elevated CRP >10 mg/L
❗️fewer prev tx
Associated w/ lower response:
❗️smoking
❗️higher patient global score / HAQ
@RheumNow #ACR24 Abstr 2325
ACR Convergence 2024 opened today with a full slate of presentations, posters and specialty meetings. The meeting began with a flip: the plenary sessions started at 9AM and the poster session began at 1030 AM. Below are some of the highlights from day one in Washington, DC.

Dr. John Cush RheumNow
10 months 3 weeks ago
RheumNow Day 1 Recap: ACR Convergence 2024 Highlights https://t.co/xjCMpzXhTE