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      Give a listen to my @RheumNow interview w Josh Hsieh, a rising star at #ACR24, who is presenting his first (of many) res

      Eric Dein ericdeinmd

      9 months 3 weeks ago
      Give a listen to my @RheumNow interview w Josh Hsieh, a rising star at #ACR24, who is presenting his first (of many) research project as a high school sophomore! His work w @NamrataRheum explores what is known- & not yet known- for cancer survival in RA https://t.co/boqwpP9CUK https://t.co/UQ37pyvZT6
      Quaack etlal. PreCARA study (vs PARA, historical control). T2T in RA improves fertility - time to pregnancy 84 days vs 1

      Richard Conway RichardPAConway

      9 months 3 weeks ago

      Quaack etlal. PreCARA study (vs PARA, historical control). T2T in RA improves fertility - time to pregnancy 84 days vs 196 days. T2T strategy also led to less NSAIDs and prednisolone. @RheumNow #ACR24 Abstr#1647 #ACRbest https://t.co/vYCCUqpCLo https://t.co/PUHJOxgGbL

      #2282
      🔬 Personalised Approach to TNFi in RA

      📊 N=50👇; 43 responders

      🔑 Findings
      💥TNFR2 rs1061622 polymorp

      Caoilfhionn Connolly CaoilfhionnMD

      9 months 3 weeks ago
      #2282 🔬 Personalised Approach to TNFi in RA 📊 N=50👇; 43 responders 🔑 Findings 💥TNFR2 rs1061622 polymorphism linked to TNFi response 💥 MR/RR alleles ⬆️ 10X odds non-response v. MM allele (OR = 10.1,p=0.04) 🎯Genotyping may guide personalized RA therapy. #ACR24 @RheumNow https://t.co/MQKZUCEPxj
      #1330
      🔬F-Calprotectin in Early RA

      ➡️ New-onset RA pts(n=104) had ⬆️ F-calprotectin vs controls(n=50)(71 v. 1

      Caoilfhionn Connolly CaoilfhionnMD

      9 months 3 weeks ago
      #1330 🔬F-Calprotectin in Early RA ➡️ New-onset RA pts(n=104) had ⬆️ F-calprotectin vs controls(n=50)(71 v. 17µg/g; p<0.001) 🔑Higher F-calprotectin linked to ⬆️ DAS28 & NSAID use ⬇️levels @ 6 months Rx ❓Role of subclinical gut inflammation in early RA #ACR24 @RheumNow
      GILZ is a negative regulator of the GC receptor, a potential steroid sparer target.
      Dr. Miceli et al identified an E3 l

      sheila RHEUMarampa

      9 months 3 weeks ago
      GILZ is a negative regulator of the GC receptor, a potential steroid sparer target. Dr. Miceli et al identified an E3 ligase of GILZ "E3-X" where deficiency leads to ⬆️ GILZ & ⬇️ inflammation. More studies needed but a promising steroid sparer option. @Rheumnow #ACR24 abs1646 https://t.co/GuVMkgOTXT
      #1165
      📊 PBMCs of IIM patients with myocarditis(n=4) showed distinct gene expression v controls(n=4) v IIM alone(n=4)

      Caoilfhionn Connolly CaoilfhionnMD

      9 months 3 weeks ago
      #1165 📊 PBMCs of IIM patients with myocarditis(n=4) showed distinct gene expression v controls(n=4) v IIM alone(n=4)👇 💥 B-cell dysregulation may drive myocarditis in IIM 🎯Key immunological insights into🫀involvement in IIM #ACR24 @RheumNow @JuliePaikMD @jhrheumatology https://t.co/PceZUS929S
      Plenary II: pregnancy in RA

      When a treat to target approach is used to achieve remission, pregnancy rates nearly simil

      Brian Jaros, MD Dr_Brian_MD

      9 months 3 weeks ago
      Plenary II: pregnancy in RA When a treat to target approach is used to achieve remission, pregnancy rates nearly similar to general population! Time to pregnancy less than half that of non-T2T comparators @RheumNow #ACR24 https://t.co/B9F9M8t9Kt
      Infertility in women with RA 2x higher

      Risk factors
      - age
      - disease activity
      - use of NSAIDs
      - use of pred >7.5mg/d

      Jiha Lee JihaRheum

      9 months 3 weeks ago
      Infertility in women with RA 2x higher Risk factors - age - disease activity - use of NSAIDs - use of pred >7.5mg/day With T2T aiming for remission, fertility improves and becomes similar to the general population #ACR24 @RheumNow ABST#1647 https://t.co/B2Tx4dju4Z
      Does psoriasis (Pso) affect radiographic progression in ankylosing spondylitis (AS)?
      A study comparing radiographic spi

      Antoni Chan MD (Prof) synovialjoints

      9 months 3 weeks ago
      Does psoriasis (Pso) affect radiographic progression in ankylosing spondylitis (AS)? A study comparing radiographic spine assessment in AS patients with and without Pso reveals no significant differences in structural lesions. Male gender is a key factor in structural… https://t.co/z34FjHtjEJ
      Is cognitive impairment in SLE driven by cell exhaustion or aging?Abstract 1514 shows that SLE patients with cognitive

      Akhil Sood MD AkhilSoodMD

      9 months 3 weeks ago

      Is cognitive impairment in SLE driven by cell exhaustion or aging? Abstract 1514 shows that SLE patients with cognitive impairment had higher levels of CD8+ (cell exhaustion) and lower levels of cell senescence markers. @RheumNow #ACR24 https://t.co/SzxTQt3oNY

      #1350
      🔬 Microbiome & RA: Impact on Disease Activity & Vascular Function

      ➡️ Salivary microbiome a/w arter

      Caoilfhionn Connolly CaoilfhionnMD

      9 months 3 weeks ago
      #1350 🔬 Microbiome & RA: Impact on Disease Activity & Vascular Function ➡️ Salivary microbiome a/w arterial stiffness (AIx)(p 0.019) ➡️ Stool microbiome a/w DAS28-CRP(p 0.027) 🔴Key taxa👇identified for each; no common taxa for both disease activity & AIx. #ACR24 @RheumNow https://t.co/54Sumzzd27
      Navigating Positive ANA: Leveraging AI for better triage

      Abstract 1526: Markus et al. developed a machine learning mod

      Akhil Sood MD AkhilSoodMD

      9 months 3 weeks ago
      Navigating Positive ANA: Leveraging AI for better triage Abstract 1526: Markus et al. developed a machine learning model to predict progression to SLE, utilizing diagnoses, meds, procedures, and labs collected 2 years before and 5 years after +ANA. @RheumNow #ACR24 https://t.co/2zzSH8Pb0e
      What is the impact of social connections on lupus?

      Abstract #1503: In an NYC SLE cohort, greater social integration and

      Akhil Sood MD AkhilSoodMD

      9 months 3 weeks ago
      What is the impact of social connections on lupus? Abstract #1503: In an NYC SLE cohort, greater social integration and support correlated with less pain, depression, disability, and frailty, while loneliness was linked to worse outcomes. @RheumNow #ACR24 #SDoH https://t.co/5OCCExee06
      Reason for consult: aortitis- evaluate for systemic causes

      Abstract 1638: Kmetova et al highlight the promising clinic

      Akhil Sood MD AkhilSoodMD

      9 months 3 weeks ago
      Reason for consult: aortitis- evaluate for systemic causes Abstract 1638: Kmetova et al highlight the promising clinical utility of calprotectin as a marker for clinically isolated aortitis @RheumNow #ACR24 https://t.co/2qPaAqWswG
      17S19 session on steroid free future
      @LesleyJacksonMD @EBRheum @BritAdlerMD

      Is a (near) steroid free future for RA, AN

      Eric Dein ericdeinmd

      9 months 3 weeks ago
      17S19 session on steroid free future @LesleyJacksonMD @EBRheum @BritAdlerMD Is a (near) steroid free future for RA, ANCA, Lupus #ACR24 @RheumNow
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