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      Novelli et al. Upadacitinib in male vs female PsA. Data from SELECT-PsA studies. Appears equivalent in males and females

      Richard Conway RichardPAConway

      2 weeks ago
      Novelli et al. Upadacitinib in male vs female PsA. Data from SELECT-PsA studies. Appears equivalent in males and females, contrasting with TNFi/IL17i data. @RheumNow #ACR25 Abstr#557 https://t.co/fMKsbCkju0
      In a novel Geri-Rheum clinic, cognitive screening revealed 35% impairment among adults >55 yrs.
      Common deficits: visu

      Jiha Lee JihaRheum

      2 weeks ago
      In a novel Geri-Rheum clinic, cognitive screening revealed 35% impairment among adults >55 yrs. Common deficits: visuospatial, attention & recall. Early geriatric screening = earlier intervention. A model for age-friendly rheum care in action. @RheumNow #ACR25 Abstract #0226 https://t.co/lIAcrZvL4H
      Heydari-Kamjani et al. Risk of DILI with avacopan. Real world study, propensity score matching. Risk DILI 2% with avacop

      Richard Conway RichardPAConway

      2 weeks ago
      Heydari-Kamjani et al. Risk of DILI with avacopan. Real world study, propensity score matching. Risk DILI 2% with avacopan vs 1.9% PBO @RheumNow #ACR25 Abstr#724 https://t.co/UhVkcXEYjF
      Ogdie et al. Week 24 results of SOLSTICE study. Guselkumab in TNF-IR in PsA. Good efficacy on skin and joint disease. No

      Richard Conway RichardPAConway

      2 weeks ago
      Ogdie et al. Week 24 results of SOLSTICE study. Guselkumab in TNF-IR in PsA. Good efficacy on skin and joint disease. No difference seen in Q4 vs Q8 weekly doses. @RheumNow #ACR25 Abstr#563 https://t.co/ztK0O9iKb8
      Observational study of fibrinogen for diagnosis of GCA

      At a cutoff of 4.7, roughly similar diagnostic performance as c

      Mike Putman EBRheum

      2 weeks ago
      Observational study of fibrinogen for diagnosis of GCA At a cutoff of 4.7, roughly similar diagnostic performance as compared to ESR/CRP Kind of neat, but does not appear to have additive benefit #ACR25 @RheumNow Abstr#0750 https://t.co/xy2qn4jHXP
      ILD found in 30% of Sjögren’s pts w/ HRCT.

      A new nomogram-based tool (AUC 0.8) predicts ILD risk using age, ESR, C3,

      Jiha Lee JihaRheum

      2 weeks ago
      ILD found in 30% of Sjögren’s pts w/ HRCT. A new nomogram-based tool (AUC 0.8) predicts ILD risk using age, ESR, C3, hypergammaglobulinemia & anti-La/SSB. Goal: guide HRCT referrals & catch ILD earlier. @RheumNow #ACR25 Abstract #0510 https://t.co/FvAprq8eol
      2-Year data from SELECT-GCA Phase 3 UPA in GCA
      Re-randomization & 52 weeks extension UPA 15mg vs. PBO

      -Risk of flar

      Aurelie Najm AurelieRheumo

      2 weeks ago
      2-Year data from SELECT-GCA Phase 3 UPA in GCA Re-randomization & 52 weeks extension UPA 15mg vs. PBO -Risk of flare 90% lower -Complete remission 70% vs 20% -Cumulative GC 1g difference -No new safety signal The quick relapse after stopping UPA indicates we are really looking https://t.co/c1khywnPNv
      Immune-Mediated Necrotizing Myopathy @EleniTiniakou #ACR25

      *Younger pts tend to have a more aggressive disease
      *IVIG an

      Rheumatology Quarterly RheumQuarterly

      2 weeks ago
      Immune-Mediated Necrotizing Myopathy @EleniTiniakou #ACR25 *Younger pts tend to have a more aggressive disease *IVIG and RTX can be considered first-line rx for anti-HMGCR and anti-SRP+, respectively *CYC and plasmapheresis may be options in cases of aggressive disease https://t.co/zWDX79gqlf
      Is there ‘bang for the buck’ using big data to help predict who will develop RA in at-risk populations and similarly to predict response to csDMARDs, TNFi and JAKi in RA?
      Abstract 0806
      Compared to belimumab, Anifrolumab associated with:
      ↑ infection risk b (HR 1.40, 95% CI 1.05–1.88)

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      Abstract 0806 Compared to belimumab, Anifrolumab associated with: ↑ infection risk b (HR 1.40, 95% CI 1.05–1.88) ↑ herpes zoster (HR 3.94) & COVID-19 (HR 1.66) No diff in mortality or hospital use 📈 3-yr infection: 38.3% vs 21.3% @RheumNow #ACR25
      Real world effectiveness of voclosporin for SLE

      Reduction in UPCR from 2.1 at b/l to 0.9 at 6 months, no improvement i

      Mike Putman EBRheum

      2 weeks ago
      Real world effectiveness of voclosporin for SLE Reduction in UPCR from 2.1 at b/l to 0.9 at 6 months, no improvement in eGFR; as expected based on trials Wonder about market share of BEL vs voclo vs ANI - anyone seen pubs on this? #ACR25 @RheumNow Abstr#0661 https://t.co/l7i7IWhLSe
      #ACR25 Abstr#775 Previous study showed plasma tRNA-derived RNA (tDR-1), produced by bacteria from the phylum Proteobacte

      Md Yuzaiful Md Yusof Yuz6Yusof

      2 weeks ago
      #ACR25 Abstr#775 Previous study showed plasma tRNA-derived RNA (tDR-1), produced by bacteria from the phylum Proteobacteria, was assoc. with lower RA activity. In 60 At-Risk CCP3+ people, Plasma tDR-1 improved prediction of RA. Need validation & adoption in practice @RheumNow https://t.co/XBmtohBEHc
      From the FOREMOST study factors predicting progression from oligo to polyarticular PsA: Female sex, enthesitis and dact

      Antoni Chan MD (Prof) synovialjoints

      2 weeks ago
      From the FOREMOST study factors predicting progression from oligo to polyarticular PsA: Female sex, enthesitis and dactylitis found to increase the risk of progression. Among patients in FOREMOST receiving PBO, prior csDMARD use was protective. Abstract#0576 @RheumNow #ACR25 https://t.co/CFMhAFgFBa
      Accdg to this retro analysis of their prospective cohort study from Toronto, 47 pts (10%) had D2M axSpA of whom 14 had t

      sheila RHEUMarampa

      2 weeks ago
      Accdg to this retro analysis of their prospective cohort study from Toronto, 47 pts (10%) had D2M axSpA of whom 14 had tx-refractory dse. D2M pts - longer symptom duration; ⬆️ASDAS, BASDAI, BASMI, BASFI & ⬆️CRP 💡Consider non-dse factors in D2M pts #ACR25 @RheumNow Abs0547 https://t.co/MUUyyELbw8
      #0191 We found that in a large South London RA cohort, use of advanced therapy in moderate disease (DAS28 3.2-5.1) gener

      Mrinalini Dey DrMiniDey

      2 weeks ago
      #0191 We found that in a large South London RA cohort, use of advanced therapy in moderate disease (DAS28 3.2-5.1) generally followed NICE guidance. Gaps often reflected telehealth limiting DAS assessment and patient hesitancy. Self-assessment tools may help. @RheumNow #ACR25 https://t.co/UMGtkfABHn
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