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Janet Pope, MD, MPH, FRCPC

Dr. Janet Pope is a Professor of Medicine in the Division of Rheumatology at the University of Western Ontario (UWO), Schulich School of Medicine, London, Ontario, Canada.  She is the Division Head in Rheumatology at St. Joseph's Health Centre, London. Her research includes studies in scleroderma, SLE and RA, including outcome measurements, clinical trials and disease manifestations. She has published over 450 peer-reviewed articles, 15 chapters, 500 abstracts and several Cochrane meta-analysis reviews. Mentoring of research students and trainees numbers more than 125. She has received the Distinguished Investigator Award from the Canadian Rheumatology Association, Rheumatologist of the Year from the Ontario Rheumatology Association, Department of Medicine Research Achievement Award, and the Dean’s Award of Excellence in Research. She has been inducted into the Canadian Academy of Health Sciences.

 

Articles By Janet Pope, MD, MPH, FRCPC

Biomarker,genes

“Age old” biomarkers in ILD and pulmonary fibrosis

At #ACR26, there was a poster on senescence being increased in SARD-ILD, including progressive pulmonary fibrosis, showing epithelial remodeling from DNA damage. This led me to look at the biomarkers of NISP (nonspecific interstitial pneumonia) that will transition to fibrosis, as the latter is considered irreversible and the former is potentially reversible.

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CAR-T

Is CAR-T cooling down in SARDs?

Tsao et al presented abstract #2773 consensus recommendations for CAR-T cell therapy in the SARDs from the Taiwan College of Rheumatology. They are thorough and outline a sensible approach.

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Pope RT cover still

Do You Have to be Overweight for GLP-1s to Work?

Are there any data that GLP-1 RA drugs can be effective if a person has a normal BMI? 

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light bulb idea

Tips for safe use of allopurinol

These are tips and hopefully the patients are abstaining from moderate alcohol and are not tipsy! Here are 5 tips that may not be totally obvious.

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CAR T on purple background

How many CAR-T’s do we need to test drive?

CAR-T at #EULAR2026 raised as many questions as it answered. Here's what we know, what we're still asking, and why the answers matter.

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lupus SLE

How to treat SLE in 2026 and beyond!

There are so many SLE trials, and over the last year, many new ideas have been suggested.

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change,future,lens,clarity

‘Strong’ treatment predictions in inflammatory myositis

Presented at EULAR 2026 London, Brepocitinib dual TYK2/JAK1 inhibitor with successful Phase 3 VALOR trial demonstrating significant improvement in skin and muscle symptoms in dermatomyositis (DM).

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syringe, pill, DMARD, Treatment, therapy

What should head-to-head studies in inflammatory arthritis teach us?

The multimillion dollar question for inflammatory arthritis prescriptions is: which drug should I use next?

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human figures on blue circle

IgG4: Rare, but new treatments on the horizon

IgG4 is a rare autoimmune disease with excessive IgG4 immunoglobulins that can affect multiple organs yielding plasma cell deposition (inflammation) and fibrosis.

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Big data

Rheumatoid arthritis and the ‘big bang’ at the ACR!

Is there ‘bang for the buck’ using big data to help predict who will develop RA in at-risk populations and similarly to predict response to csDMARDs, TNFi and JAKi in RA?

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