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Rheumatoid Arthritis

      RT @drdavidliew: Pregnancy is a minefield for RA pts:
      dx activity➡️preg risk
      PNL➡️preg risk, but dx activity pro
      3 years 7 months ago
      Pregnancy is a minefield for RA pts: dx activity➡️preg risk PNL➡️preg risk, but dx activity proxy? bring on Swedish/Danish linked data: 1739 RA preg matched 1:10 ⬆️pre-term/SGA risk with bDMARDs/PNL adj for dx activity: less bad, but still concern? OP0210 #EULAR2021 @RheumNow https://t.co/AlwFtmGcZH
      RT @AurelieRheumo: In the ESPOIR cohort of 813 RA followed for 10 years, polypharmacy associated w/ less DAS28 ESR Remi
      3 years 7 months ago
      In the ESPOIR cohort of 813 RA followed for 10 years, polypharmacy associated w/ less DAS28 ESR Remission at 5 (45.0% in vs. 56.3% (p=0.03)) and 10 yrs (32.5% vs. 67.5% (p=0.06)) BUT no longer significant when adjusted for comorbidities! #EULAR2021 @Rheumnow #OP0098 https://t.co/pSrr1dzKFP
      RT @AurelieRheumo: Acute Coronary Syndrom incidence in > 24,000 RA from Nordic registers followed up to 5 yrs = 5.5/1
      3 years 7 months ago
      Acute Coronary Syndrom incidence in > 24,000 RA from Nordic registers followed up to 5 yrs = 5.5/1000 pyrs. After 5yrs RTX show > risk of ACS compared to ETA. In patient with >= 2 previous DMARDs ABA, INF and RTX > risk of ACS compared to ETA. #EULAR2021 @Rheumnow #OP0114 https://t.co/MjW9LI2cjt
      RT @AurelieRheumo: Patients with RA > 70yo and risk of severe infection: which therapeutic strategy is the safest?
      #E
      3 years 7 months ago
      Patients with RA > 70yo and risk of severe infection: which therapeutic strategy is the safest? #EULAR2021 @Rheumnow #OP0116
      RT @AurelieRheumo: Dr Yoshida analyze data from US registry 40,721 RA patients. High 2.11 [1.13, 3.96] and moderate 1.97
      3 years 7 months ago
      Dr Yoshida analyze data from US registry 40,721 RA patients. High 2.11 [1.13, 3.96] and moderate 1.97 [1.13, 3.43] CDAI associated w/ > HR of major adverse CV events. HRs decrease during follow up. Tight and early disease control reduces CV burden! #EULAR2021 @Rheumnow #OP0101 https://t.co/A0ZYE4v8uf
      RT @AurelieRheumo: In 16,448 RA from ACR’s RISE registry: no difference in disease activity TNFi and non-TNFi at 12 mo
      3 years 7 months ago
      In 16,448 RA from ACR’s RISE registry: no difference in disease activity TNFi and non-TNFi at 12 months. Stratified analysis: ⬆️disease activity for TNFi vs. non TNFi in patients of Black and Asian ethnicity. To be confirmed in independent cohorts. #EULAR2021 @Rheumnow #OP0117 https://t.co/7bFnOKR9uz
      RT @AurelieRheumo: MTX or ETA which one withdraw first? @RADoctor SEAM-RA trial: PROs following withdrawal of MTX or ETN
      3 years 7 months ago
      MTX or ETA which one withdraw first? @RADoctor SEAM-RA trial: PROs following withdrawal of MTX or ETN in RA patients with sustained SDAI remission receiving combination ETN+MTX. ETA > MTX for maintaining SDAI remission at W48 (49.5%-28.7% P=0.004) #EULAR2021 @Rheumnow #OP0118 https://t.co/MSOclXGMEK
      RT @AurelieRheumo: Can we predict pre-clinical RA-ILD?
      @Juge_P_A ESPOIR cohort. model w/ 4 variables: male gender, olde
      3 years 7 months ago
      Can we predict pre-clinical RA-ILD? @Juge_P_A ESPOIR cohort. model w/ 4 variables: male gender, older age @ diag, mean DAS-28 over follow-up and MUC5B variant ▶️ preclinical ILD after 13 years of RA w/ AUC=0.82 CI 95% (0.72-0.91) (Sens 80%, Spe 56%) #POS0095 @Rheumnow #EULAR2021 https://t.co/bPyidNhNuO
      RT @Janetbirdope: Can machine learning show JAKi effects for safety? Off target binding predicted in #tofacitinib 58,
      3 years 7 months ago
      Can machine learning show JAKi effects for safety? Off target binding predicted in #tofacitinib 58, #baricitinib 41 but NO pathway for thrombosis or viral infection. Could have repurposing for + effects on lung vasculature & antifibrotic effects POS0091 #EULAR2021 @RheumNow
      RT @Janetbirdope: MACE events with #JAKi is as clear as mud! You voted >50% NOT Sure 1/3 only some Jakis vs MACE in #
      3 years 7 months ago
      MACE events with #JAKi is as clear as mud! You voted >50% NOT Sure 1/3 only some Jakis vs MACE in #TNFi! Dunno #EULAR2021 @RheumNow @eular_org https://t.co/vWUgKSwAap
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