Lupus

Janet Pope Janetbirdope
2 years 4 months ago
#SLE #EULAR recommendations What is new - use LESS #glucocorticoids, aim for none or 5 mg/d or less, use #biologics early if needed to prevent damage, #lupus #nephritis consider less pulse dose if using, voclosporin vs Belimumab ? it depends @RheumNow #EULAR2023 https://t.co/Ylnnl3pHOK


Bella Mehta bella_mehta
2 years 4 months ago
Diagnostic delay in #lupus is really prevalent!
#EULAR2023 @RheumNow
20% with new lupus diagnosis are hospitalized!
20% diagnosis is delayed for more than 3 months! https://t.co/1vCcezBrQS


Bella Mehta bella_mehta
2 years 4 months ago
Meds in #lupus at #EULAR2023 recs
- HCQ first line therapy. Target dose remains the same. Some discussion on monitoring levels if possible
- MAIN CHANGE - Glucocorticoids to be minimized (only use for bridging). Nephrologists more so in favor of steroid free remission @RheumNow https://t.co/d8WnUOgrwq


Bella Mehta bella_mehta
2 years 4 months ago
CAR-T cells in refarctory SLE- long term data presented #EULAR2023
Pts did well except some mild cytopenias. Pts remained in remission.
Maybe a good option in the near future for refractory pts!
@RheumNow https://t.co/NWoFBipOiQ


Bella Mehta bella_mehta
2 years 4 months ago
With the single cell RNA sequencing analysis being my more affordable (relatively) and widely used! Science is moving forward. Highlights in basic science and translational data #EULAR2023 @RheumNow https://t.co/sS7xLeNyLW


Md Yuzaiful Md Yusof Yuz6Yusof
2 years 4 months ago
#EULAR2023 #LB0005 Can we improve trial design of Bcell depletion in #SLE? Feasibility RCT of RTX in organ specific MSK showed: a)feasible to use ultrasound & clinical as endpoints, b)new tool LAMDA is responsive, c)potential worsening before later improvement with RTX @RheumNow https://t.co/kGDZ6EqLtq

Risk of poor pregnancy outcomes in lupus patients continues to remain high, especially in the setting of high disease activity. Preliminary data from a lupus pregnancy LEGACY cohort presented at EULAR 2023 raise concern.

Dr. John Cush RheumNow
2 years 4 months ago
Promising new therapies in SLE
Dr. Yuz Yusof ( @Yuz6Yusof ) weighs in.
The pharmacology treatment in SLE is a rapidly expanding field of research that provides excitement and optimism to both the patients and the clinicians.
https://t.co/0G6EMYp2mb https://t.co/Yc31sR4fRE


Dr. John Cush RheumNow
2 years 4 months ago
Tune it at 1pm EST for RheumNow's daily #EULAR23 recaps. You can find us live on Twitter, YouTube and LinkedIn. https://t.co/t531csjXo8


Md Yuzaiful Md Yusof Yuz6Yusof
2 years 4 months ago
#EULAR2023 #OP0290 Heterogeneity in #SLE is not only disease features but think of ANCESTRY. Data from BILAG-BR registry showed worse outcomes in people of Black and South Asian treated with either Rituximab or Belimumab (adjusted for deprivation index) @RheumNow https://t.co/bcdu9RIFSx


Bella Mehta bella_mehta
2 years 4 months ago
Predictors of first hospitalizations due to disease activity and infections in #lupus 1341 pts from multicenter latin american cohort. 33% with atleast one hospitalization, and 3/4th due to disease activity.
@rheumnow #EULAR2023 abt#POS0169 https://t.co/vbJU4220is


Bella Mehta bella_mehta
2 years 4 months ago
Evaluation of diagnostic performance of ACR 1997, SLICC 2012 and EULAR /ACR diagnostic crieteria in childhood onset #SLE - SLICC highest sensitivity early in the disease,
ACR1997 has the highest specificity both at diagnosis ans over time.
@RheumNow #EULAR2023 abst#POS0136

Md Yuzaiful Md Yusof Yuz6Yusof
2 years 4 months ago
#EULAR2023 #POS1124 My newly diagnosed patients & their carers often expressed heightened anxiety with poor quality web info about #SLE. Thank you @LupusEurope for this wonderful effort 👏. Available in most European languages too @RheumNow https://t.co/cr5Ls117xM
