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Vasculitis

      LBA0001 UPA in GCA- Phase 2 RCT

      15mg UPA with 26w steroid taper showed
      ⬆️ efficacy
      ⬇️ steroid use
      vs placebo wi
      6 months ago
      LBA0001 UPA in GCA- Phase 2 RCT 15mg UPA with 26w steroid taper showed ⬆️ efficacy ⬇️ steroid use vs placebo with 52w steroid taper Potential new target on the horizon for #GCA?? @RheumNow #EULAR2024
      #wasup in #GCA?

      #upadacitinib +RCT in #temporal #arteritis LBA0001

      Residual #inflammation in 1/3 of pts at 6 mo #Rx w
      6 months ago
      #wasup in #GCA? #upadacitinib +RCT in #temporal #arteritis LBA0001 Residual #inflammation in 1/3 of pts at 6 mo #Rx w #TCZ on repeat TA Bx OP0621 #PMR cases #Leflunomide beats #MTX for #pred sparing ⬇️relapses But MTX dose was low POS0280 #EULAR2024 @RheumNow @eular_org
      #EULAR2024 POS1420 A cohort study with 1/3 each with GCA, PMR and GCA+PMR found that at 6mth, 16% of patients had new di
      #EULAR2024 POS1420 A cohort study with 1/3 each with GCA, PMR and GCA+PMR found that at 6mth, 16% of patients had new diabetes/diabetes worsened. Worse in GCA+PMR group with the greatest GC accumulation. Call for better GC-sparing strategy @RheumNow https://t.co/ex7u83bVfj
      #EULAR2024 POS0742 A single cohort study showed for non-criteria #APS, cardiac manifestation (valvular dysfunction &
      #EULAR2024 POS0742 A single cohort study showed for non-criteria #APS, cardiac manifestation (valvular dysfunction & regurgitation) was more common in Triple Ab+ vs Non-Triple Ab. We should monitor and consider an echocardiogram for this group of patient @RheumNow https://t.co/VxFUSpjaG1
      If your GCA flares, do you get the same features as you did at diagnosis?

      20% of the time it can be new, so keep on doi
      6 months 1 week ago
      If your GCA flares, do you get the same features as you did at diagnosis? 20% of the time it can be new, so keep on doing the checklist! (also, visual flares uncommon - the power of pred) #EULAR2024 POS0110 @MayoClinic @MdWarrington @RheumNow https://t.co/hkF8vJT6HI
      Just a reminder - large vessel involvement is very common in GCA, and lines up with aortic dilatation. And if you don’
      6 months 1 week ago
      Just a reminder - large vessel involvement is very common in GCA, and lines up with aortic dilatation. And if you don’t look, you won’t find… #EULAR2024 POS0932 @RheumNow https://t.co/2uZTu0B18Z
      Prof Hellmich takes us through “What is new?” In ANCA #vasculitis

      A tour de force in management strategies and, con
      6 months 1 week ago
      Prof Hellmich takes us through “What is new?” In ANCA #vasculitis A tour de force in management strategies and, continuing a theme of #EULAR2024, ends with a study suggesting the potential of #CAR-T! @RheumNow https://t.co/K3dDqZhUvD
      Predicting who will develop
      ▶️#GCA
      In #Swedish study with
      #PMR

      ⬆️ in HIGH ESR/CRP

      ⬆️female

      ⬇️ if hi
      6 months 1 week ago
      Predicting who will develop ▶️#GCA In #Swedish study with #PMR ⬆️ in HIGH ESR/CRP ⬆️female ⬇️ if hip pain/stiffness Not all sig 1 mo after #prednisone started Only 9% with #polymyalgia #rheumatica developed #GCA ? ⬇️GCA % in PMR over time #POS0411 @eular_org @RheumNow https://t.co/UMhxlYd0Pv
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