Vasculitis

Nouf Al hemmadi NoufAhmedAlham2
1 year 3 months ago
Maintenance of remission in GPA/MPA.
RTX for 48 months sounds good to me.
#EULAR2024 https://t.co/5YGwOHhCuX


Janet Pope Janetbirdope
1 year 3 months ago
#wasup in #GCA?
#upadacitinib +RCT in #temporal #arteritis LBA0001
Residual #inflammation in 1/3 of pts at 6 mo #Rx w #TCZ on repeat TA Bx
OP0621
#PMR cases
#Leflunomide beats #MTX for
#pred sparing
⬇️relapses
But MTX dose was low
POS0280
#EULAR2024 @RheumNow @eular_org

Md Yuzaiful Md Yusof Yuz6Yusof
1 year 3 months ago
#EULAR2024 POS1420 A cohort study with 1/3 each with GCA, PMR and GCA+PMR found that at 6mth, 16% of patients had new diabetes/diabetes worsened. Worse in GCA+PMR group with the greatest GC accumulation. Call for better GC-sparing strategy @RheumNow https://t.co/ex7u83bVfj


Md Yuzaiful Md Yusof Yuz6Yusof
1 year 3 months ago
#EULAR2024 POS0742 A single cohort study showed for non-criteria #APS, cardiac manifestation (valvular dysfunction & regurgitation) was more common in Triple Ab+ vs Non-Triple Ab. We should monitor and consider an echocardiogram for this group of patient @RheumNow https://t.co/VxFUSpjaG1


David Liew drdavidliew
1 year 3 months ago
If your GCA flares, do you get the same features as you did at diagnosis?
20% of the time it can be new, so keep on doing the checklist!
(also, visual flares uncommon - the power of pred)
#EULAR2024 POS0110 @MayoClinic @MdWarrington @RheumNow https://t.co/hkF8vJT6HI


David Liew drdavidliew
1 year 3 months ago
Just a reminder - large vessel involvement is very common in GCA, and lines up with aortic dilatation. And if you don’t look, you won’t find…
#EULAR2024 POS0932 @RheumNow https://t.co/2uZTu0B18Z


Mrinalini Dey DrMiniDey
1 year 3 months ago
Prof Hellmich takes us through “What is new?” In ANCA #vasculitis
A tour de force in management strategies and, continuing a theme of #EULAR2024, ends with a study suggesting the potential of #CAR-T!
@RheumNow https://t.co/K3dDqZhUvD


Janet Pope Janetbirdope
1 year 3 months ago
Predicting who will develop
▶️#GCA
In #Swedish study with
#PMR
⬆️ in HIGH ESR/CRP
⬆️female
⬇️ if hip pain/stiffness
Not all sig 1 mo after #prednisone started
Only 9% with #polymyalgia #rheumatica developed #GCA
? ⬇️GCA % in PMR over time
#POS0411 @eular_org @RheumNow https://t.co/UMhxlYd0Pv


Janet Pope Janetbirdope
1 year 3 months ago
Leflunomide for #PMR?
✅ #Leflunomide FAR more effective than #MTX in #polymyalgia #rheumatica
V fast withdrawal of #prednisone
#LEF ~4 to 5 months
#MTX 30 mos!
⬇️flares w LEF
😮
#EULAR2024 @RheumNow @eular_org
@SebaUltraTrail https://t.co/2hk0yMH6gY


David Liew drdavidliew
1 year 3 months ago
Does TCZ switch off GCA histopathologically?
GCA pts still on TCZ (median 2.4y duration) had repeat temporal artery biopsy (contralat)
Despite serological remission on TCZ, a heap had active histopath findings & PET still active. Scary
#EULAR2024 OP0233 Reggio Emilia @RheumNow https://t.co/TKBUP5p4R0


Janet Pope Janetbirdope
1 year 3 months ago
#Editor’s #Choice
@MatsJunek
Who #relapses in
#ANCA #vasculitis
In #Pexivas trial
#Renal #failure may be protective from relapses.
Seems to be the case in renal #lupus #GN too~my opinion
?Why 🤷
#EULAR2024 #EULARBEST @ARD_BMJ
@RheumNow @eular_org @ACR_Journals https://t.co/kUD1qjnwqE


David Liew drdavidliew
1 year 3 months ago
I have to say: upadacitinib looks very decent for GCA. Not a panacea, but it definitely does something & good safety during trial.
Would love to eventually see:
- H2H comparative effect vs toci, secukinumab
- structural outcomes
- long-term safety
#EULAR2024 PBA0001 @RheumNow https://t.co/pHZgCKsoA9 https://t.co/5BxCkkLPti
- https://twitter.com/drdavidliew/status/1801223940318351737/photo/1
- https://twitter.com/drdavidliew/status/1801223940318351737/photo/1
- https://twitter.com/drdavidliew/status/1801223940318351737/photo/1
- https://twitter.com/drdavidliew/status/1801223940318351737/photo/1
- https://twitter.com/drdavidliew/status/1801196482995101974


Peter Nash drpnash
1 year 3 months ago
LONG-TERM EFFICACY TOCILIZUMAB AFTER ULTRA-SHORT GC TO TREAT GCA: 3 Yr FOLLOW-UP OF THE GUSTO TRIAL
3 day GC pulse immediate 12 mths Toci 85% drug free remission at 4 yrs! @rheumnow #EULAR2024